Journal
CELL
Volume 161, Issue 2, Pages 197-198Publisher
CELL PRESS
DOI: 10.1016/j.cell.2015.03.046
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Funding
- NIDDK NIH HHS [P30 DK020572] Funding Source: Medline
- NIGMS NIH HHS [R37- GM062261, R01 GM062261, R01-GM050403, R01 GM050403, R37 GM062261] Funding Source: Medline
- NINDS NIH HHS [R01-NS064015, R01 NS064015] Funding Source: Medline
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Lysosomes provide a major source for cellular cholesterol; however, most of this cholesterol is trafficked to the plasma membrane via unknown mechanisms. Chu et al. identify an unexpected role for peroxisomes in the transport of cholesterol from the lysosome to the plasma membrane via a lysosome-peroxisome membrane contact site.
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