Journal
JOURNAL OF THE NEUROLOGICAL SCIENCES
Volume 443, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jns.2022.120489
Keywords
Secondhand smoking; Stroke; Haemorrhagic stroke; Ischaemic stroke; SIREN
Categories
Funding
- National Institutes of Health [U54HG007479, R01NS107900, U01HG010273, R01NS107900-02S1, R01NS115944-01, 3U24HG009780-03S5, 1R01NS114045-01, 1R13NS115395-01A1, D43TW012030]
- Brain Pool Fellowship of the National Research Foundation of Korea [2020H1D3A1A04081265]
- National Research Foundation of Korea [2020H1D3A1A04081265] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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This study found a positive association between secondhand smoke exposure and stroke among indigenous Africans. Culturally relevant primary prevention strategies targeting secondhand smoke exposure might be promising in preventing stroke among Africans.
Background: Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans.Objective: To evaluate the association of SHSE with stroke among indigenous Africans.Methods: We analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05.Results: Multivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes.Conclusion: Culturally relevant primary prevention strategies targeted at SHSE might be promising in preventing stroke among Africans.
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