4.8 Article

Total Syntheses of Nominal and Actual Prorocentin

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Total Syntheses of Scabrolide A and Nominal Scabrolide B

Zhanchao Meng et al.

Summary: The marine natural product scabrolide A was synthesized by a series of chemical reactions, including rearrangement, ring closure, and epoxidation, to form the carbon backbone and the correct stereochemistry of the compound.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

Review Chemistry, Multidisciplinary

Gold-Catalyzed Synthesis of Spirocycles: Recent Advances

Somnath Ganguly et al.

Summary: This review article provides an overview of gold-catalyzed reactions for the formation of spirocycles from various substrates, including methodologies, applications, and mechanistic insights.

CHEMISTRYSELECT (2022)

Article Chemistry, Multidisciplinary

The Formosalides: Structure Determination by Total Synthesis

Saskia Schulthoff et al.

Summary: This article describes how total synthesis was used to confirm and assign the structure of cytotoxic marine macrolides, and discusses the use of modular design and catalyst-controlled transformations to achieve the preparation of stereo isomers.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Collective Total Synthesis of Casbane Diterpenes: One Strategy, Multiple Targets

Lorenz E. Loeffler et al.

Summary: This paper presents a new approach to chemical synthesis that allows for the preparation of a variety of casbane derivatives, especially the more highly oxygenated and arguably more relevant members of the family. Key design elements include catalyst-controlled intramolecular cyclopropanation, chain extension of stereoisomeric cyclopropane building blocks, and ring-closing alkyne metathesis. The concise total syntheses of depressin, yuexiandajisu A, and ent-pekinenin C demonstrate the effectiveness of this method.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Organic

Prorocentroic Acid, a Neuroactive Super-Carbon-Chain Compound from the Dinoflagellate Prorocentrum hoffmannianum

Humberto J. Dominguez et al.

Summary: The research determined the relative configuration of Prorocentroic acid and its effects on murine cortical neurons. Long-term exposure to subtoxic concentrations caused significant reorganization of neuronal signaling, potentially through the activation of plasticity processes.

ORGANIC LETTERS (2021)

Article Chemistry, Multidisciplinary

Total Synthesis of Limaol

Stephan N. Hess et al.

Summary: Limaol, a marine-derived C40-polyketide, is unique in structure due to the nonthermodynamic array of four skipped methylene substituents on its hydrophobic tail. This distinctive segment was assembled using a two-directional approach and coupled to the polyether domain through an allyl/alkenyl Stille reaction under neutral conditions. The core region was prepared through several key steps, including asymmetric propargylation catalyzed by 3,3'-dibromo-BINOL, gold-catalyzed spirocyclization, and substrate-controlled allylation to introduce the southern sector.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

A Unified Approach to Polycyclic Alkaloids of the Ingenamine Estate: Total Syntheses of Keramaphidin B, Ingenamine, and Nominal Njaoamine I

Zhanchao Meng et al.

Summary: The synthesis of polycyclic marine alkaloids involves diverse reaction pathways and catalysts. The combination of RCAM and macrolactamization is particularly significant in this process.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Chagosensine: A Riddle Wrapped in a Mystery Inside an Enigma

Marc Heinrich et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Multidisciplinary

Total Synthesis Provides Strong Evidence: Xestocyclamine A is the Enantiomer of Ingenamine

Zhanchao Meng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Multidisciplinary

Metathesis at an Implausible Site: A Formal Total Synthesis of Rhizoxin D

Pol Karier et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Total Synthesis of Belizentrin Methyl Ester: Report on a Likely Conquest

Felix Anderl et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Review Chemistry, Multidisciplinary

Gold-Catalyzed Polycyclization Toward Natural Products Synthesis

Patrick Y. Toullec et al.

ISRAEL JOURNAL OF CHEMISTRY (2018)

Review Chemistry, Multidisciplinary

Gold-Catalyzed Hydrofunctionalizations and Spiroketalizations of Alkynes as Key Steps in Total Synthesis

Daniel Pflaesterer et al.

ISRAEL JOURNAL OF CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

Total Synthesis of Putative Chagosensine

Marc Heinrich et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Catalysis-Based Total Syntheses of Pateamine A and DMDA-Pat A

Chun-Xiang Zhuo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Review Chemistry, Multidisciplinary

Gold Catalysis for Heterocyclic Chemistry: A Representative Case Study on Pyrone Natural Products

Alois Fuerstner

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Organic

Hydroxyl-Assisted trans-Reduction of 1,3-Enynes: Application to the Formal Synthesis of (+)-Aspicilin

Sebastian Schaubach et al.

SYNTHESIS-STUTTGART (2017)

Article Plant Sciences

Limaol: A Polyketide from the Benthic Marine Dinoflagellate Prorocentrum lima

A. Reum Yang et al.

JOURNAL OF NATURAL PRODUCTS (2017)

Article Chemistry, Organic

Total Synthesis of (-)-Phorbaketal A

Seewon Joung et al.

ORGANIC LETTERS (2017)

Article Chemistry, Multidisciplinary

Concise Synthesis of a PateamineA Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling

Chun-Xiang Zhuo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Applied

Convergent Synthesis of Menaquinone-7 (MK-7)

Aneta Baj et al.

ORGANIC PROCESS RESEARCH & DEVELOPMENT (2016)

Article Biochemistry & Molecular Biology

Design, synthesis, and biological evaluation of air-stable nafuredin-γ analogs as complex I inhibitors

Masaki Ohtawa et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2015)

Article Chemistry, Multidisciplinary

Concise Total Syntheses of Amphidinolides C and F

Gaelle Valot et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

Review Chemistry, Multidisciplinary

From Understanding to Prediction: Gold- and Platinum-Based π-Acid Catalysis for Target Oriented Synthesis

Alois Fuerstner

ACCOUNTS OF CHEMICAL RESEARCH (2014)

Article Chemistry, Multidisciplinary

Synthesis, Molecular Editing, and Biological Assessment of the Potent Cytotoxin Leiodermatolide

Damien Mailhol et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Organic

Belizentrin, a Highly Bioactive Macrocycle from the Dinoflagellate Prorocentrum belizeanum

Humberto J. Dominguez et al.

ORGANIC LETTERS (2014)

Article Chemistry, Multidisciplinary

Total Synthesis of Amphidinolide F

Gaelle Valot et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Article Chemistry, Multidisciplinary

Total Syntheses and Biological Reassessment of Lactimidomycin, Isomigrastatin and Congener Glutarimide Antibiotics

Kevin Micoine et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

Article Chemistry, Multidisciplinary

Formal Total Synthesis of the Algal Toxin (-)-PolycavernosideA

Lennart Brewitz et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

Article Chemistry, Organic

Asymmetric Transfer Hydrogenation of Functionalized Acetylenic Ketones

Zhijia Fang et al.

JOURNAL OF ORGANIC CHEMISTRY (2013)

Article Chemistry, Multidisciplinary

Scope and Mechanism of the Pt-Catalyzed Enantioselective Diboration of Monosubstituted Alkenes

John R. Coombs et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Chemistry, Medicinal

Okadaic Acid: More than a Diarrheic Toxin

Vanessa Valdiglesias et al.

MARINE DRUGS (2013)

Article Chemistry, Organic

Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol

Labros G. Meimetis et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2012)

Article Chemistry, Multidisciplinary

The Leiodolide B Puzzle

Alexandre Larivee et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Chemistry, Multidisciplinary

Second-Generation Total Synthesis of Spirastrellolide F Methyl Ester: The Alkyne Route

Stefan Benson et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Review Chemistry, Multidisciplinary

Recent advances in Sonogashira reactions

Rafael Chinchilla et al.

CHEMICAL SOCIETY REVIEWS (2011)

Article Chemistry, Multidisciplinary

Gram-Scale Synthesis of Iejimalide B

Julien Gagnepain et al.

CHEMISTRY-A EUROPEAN JOURNAL (2011)

Article Chemistry, Multidisciplinary

Catalysis-Based and Protecting-Group-Free Totall Syntheses of the Marine Oxylipins Hybridalactone and the Ecklonialactones A, B, and C

Volker Hickmann et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Chemistry, Organic

Asymmetric Propargylation of Ketones Using Allenylboronates Catalyzed by Chiral Biphenols

David S. Barnett et al.

ORGANIC LETTERS (2011)

Article Chemistry, Organic

Synthesis of the C22-C37 segment of prorocentin

Atsushi Takemura et al.

TETRAHEDRON LETTERS (2011)

Article Chemistry, Multidisciplinary

Total Synthesis of (-)-Virginiamycin M-2

Jie Wu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Elementary Steps in Gold Catalysis: The Significance of gem-Diauration

Guenter Seidel et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Synthesis of the QRSTU Domain of Maitotoxin and Its 85-epi- and 86-epi-Diastereoisomers

K. C. Nicolaou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Chemistry, Multidisciplinary

Belizeanolide, a Cytotoxic Macrolide from the Dinoflagellate Prorocentrum belizeanum

Jose G. Napolitano et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Review Chemistry, Multidisciplinary

Total Syntheses of Amphidinolides B1, B4, G1, H1 and Structure Revision of Amphidinolide H2

Alois Fuerstner et al.

CHEMISTRY-A EUROPEAN JOURNAL (2009)

Review Biochemistry & Molecular Biology

Structural revisions of natural products by total synthesis

Martin E. Maier

NATURAL PRODUCT REPORTS (2009)

Article Chemistry, Multidisciplinary

A Synthesis-Driven Structure Revision of Berkelic Acid Methyl Ester

Philipp Buchgraber et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Review Chemistry, Multidisciplinary

The continuing saga of the marine polyether biotoxins

K. C. Nicolaou et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Article Chemistry, Multidisciplinary

A versatile protocol for Stille-Migita cross coupling reactions

Alois Fuerstner et al.

CHEMICAL COMMUNICATIONS (2008)

Article Chemistry, Organic

Activation of molecular oxygen and its use in stereoselective tetrahydrofuran-syntheses from δ,ε-unsaturated alcohols

Barbara Menendez Perez et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2008)

Article Chemistry, Organic

Hexafluoroisopropanol as a unique solvent for stereoselective lododesilylation of vinylsilanes

Elizabeth A. Ilardi et al.

ORGANIC LETTERS (2008)

Article Chemistry, Organic

A concise route to two distinct E-ring structures of ciguatoxins

Masayuki Inoue et al.

HETEROCYCLES (2007)

Review Chemistry, Multidisciplinary

Catalytic carbophilic activation: Catalysis by platinum and gold pi acids

Alois Fuerstner et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Chemistry, Multidisciplinary

What is amphidinolide V? Report on a likely conquest

Alois Fuerstner et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Review Chemistry, Multidisciplinary

Total syntheses of amphidinolide H and G

Alois Fuerstner et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Chemistry, Organic

Divergent synthesis of the tetracyclic ethers of 6-X-7-6 ring systems

M Inoue et al.

TETRAHEDRON (2003)

Article Chemistry, Multidisciplinary

Allylic sulfones containing triene moieties as key synthons for carotenoid synthesis

M Ji et al.

HELVETICA CHIMICA ACTA (2003)

Review Chemistry, Multidisciplinary

Total syntheses of the phytotoxic lactones herbarumin I and II and a synthesis-based solution of the pinolidoxin puzzle

A Fürstner et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Article Chemistry, Organic

Ring-closing alkyne metathesis.: Application to the total synthesis of sophorolipid lactone

A Fürstner et al.

JOURNAL OF ORGANIC CHEMISTRY (2000)

Article Chemistry, Multidisciplinary

Facile enantioselective synthesis of propargylic alcohols by direct addition of terminal alkynes to aldehydes

DE Frantz et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)