Hemodynamic Characterization of Neonates With Congenital Diaphragmatic Hernia-Associated Pulmonary Hypertension by Cardiac Catheterization

We examined the results of cardiac catheterization in infants with congenital diaphragmatic hernia (CDH) from 2009 to 2020. Catheterization confirmed pulmonary arterial hypertension in all cases (n = 17) and identified left ventricular (LV) diastolic dysfunction (LVDD) in 53%. LVDD was associated with greater respiratory morbidity. Preprocedural noninvasive assessment showed inconsistent agreement with catheterization results. (J Pediatr 2023;255:230-5).

Automated summary

We analyzed the outcomes of cardiac catheterization in infants diagnosed with congenital diaphragmatic hernia (CDH) between 2009 and 2020. The results showed that all cases (n = 17) had pulmonary arterial hypertension confirmed by catheterization, and 53% of cases had left ventricular diastolic dysfunction (LVDD). LVDD was found to be associated with increased respiratory morbidity. Noninvasive assessments before the procedure did not consistently agree with the catheterization results.