4.5 Article

Neurocognitive impairment in multiple sclerosis and its association with thiol-disulfide homeostasis and ischemia-modified albumin

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Oxidative stress activity of fingolimod in multiple sclerosis

Recep Yevgi et al.

Summary: The study found that levels of TOS in MS patients were significantly higher before fingolimod treatment compared to the control group, but decreased significantly in the third month of treatment. There was an increase in TAC levels after treatment, but no significant difference compared to the control group. The study also demonstrated a positive correlation between pre-and post-treatment EDSS scores and TOS values, confirming a close relationship between MS and oxidative stress.

CLINICAL NEUROLOGY AND NEUROSURGERY (2021)

Article Medicine, General & Internal

Plasma thiol/disulphide homeostasis changes in patients with relapsing-remitting multiple sclerosis

Serkan Ozben et al.

Summary: Our study revealed that RRMS patients experience increased oxidative stress during relapses, characterized by decreased native and total thiol levels, and increased disulphide levels. The dynamic changes in TDH levels may serve as a novel and special biomarker for the diagnosis and prognosis of RRMS patients.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

Article Clinical Neurology

Baseline characteristics and effects of fingolimod on cognitive performance in patients with relapsing-remitting multiple sclerosis

Dawn W. Langdon et al.

Summary: The study found that lower cognitive baseline scores correlated with higher disease burden, longer disease duration, and older age in patients with multiple sclerosis. Fingolimod treatment significantly improved cognitive processing speed and attention, regardless of baseline cognitive status.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

Article Medicine, General & Internal

Variations of Thiol-Disulfide Homeostasis Parameters after Treatment with H1-Antihistamines in Patients with Chronic Spontaneous Urticaria

Clara Matei et al.

Summary: Investigating 30 patients with chronic spontaneous urticaria, the study revealed altered levels of TDHPs which normalized after treatment with H1-antihistamines, leading to symptom relief. These findings suggest the potential role of TDHPs in the defense against oxidative stress and in monitoring H1-antihistamine therapy in patients with chronic spontaneous urticaria.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Clinical Neurology

Cognition in multiple sclerosis: State of the field and priorities for the future

James F. Sumowski et al.

NEUROLOGY (2018)

Review Health Care Sciences & Services

Fingolimod for multiple sclerosis and emerging indications: appropriate patient selection, safety precautions, and special considerations

Ilya Ayzenberg et al.

THERAPEUTICS AND CLINICAL RISK MANAGEMENT (2016)

Article Cell Biology

Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly

Marilia Baierle et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)

Article Medical Laboratory Technology

A novel and automated assay for thiol/disulphide homeostasis

Ozcan Erel et al.

CLINICAL BIOCHEMISTRY (2014)

Article Medical Laboratory Technology

Ischemia modified albumin is an indicator of oxidative stress in multiple sclerosis

Ozgur Aydin et al.

BIOCHEMIA MEDICA (2014)

Article Medical Laboratory Technology

Peripheral oxidative stress in relapsing-remitting multiple sclerosis

Inmaculada Tasset et al.

CLINICAL BIOCHEMISTRY (2012)

Article Clinical Neurology

Recommendations for a Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS)

D. W. Langdon et al.

MULTIPLE SCLEROSIS JOURNAL (2012)