4.6 Article

Spatially selective stimulation of the pig vagus nerve to modulate target effect versus side effect

Related references

Note: Only part of the references are listed.
Article Cell Biology

Mapping the functional anatomy and topography of the cardiac autonomic innervation for selective cardiac neuromodulation using MicroCT

Bettina Kronsteiner et al.

Summary: This study established a topographical and anatomical map of the superior cardiac vagal branch, providing valuable anatomical information for future approaches of selective cardiac neurostimulation.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

Review Clinical Neurology

Responsive Vagus Nerve Stimulation for Drug Resistant Epilepsy: A Review of New Features and Practical Guidance for Advanced Practice Providers

Breanne Fisher et al.

Summary: Vagus nerve stimulation (VNS) is a safe and effective therapy for drug resistant epilepsy that has been available for over 20 years. The therapy has evolved to provide advanced features and closed-loop stimulation, and dedicated VNS clinics managed by Advanced Practice Providers (APPs) have improved access and continuity of care for patients. APPs play an integral role in comprehensive healthcare teams, providing guidance and support for those managing VNS patients.

FRONTIERS IN NEUROLOGY (2021)

Article Biochemical Research Methods

Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation

Kirill Aristovich et al.

Summary: Optimized electrical neuromodulation of the cervical vagus nerve can selectively affect respiratory rate or heart rate, revealing organ-specific organization of neural fibers in the cervical vagus nerve.

JOURNAL OF NEUROSCIENCE METHODS (2021)

Article Multidisciplinary Sciences

Selective stimulation of the ferret abdominal vagus nerve with multi-contact nerve cuff electrodes

Jonathan A. Shulgach et al.

Summary: Vagus nerve stimulation (VNS) holds promise for affecting gastrointestinal function and treating diseases, but off-target effects can lead to major side effects. This study successfully demonstrated selective activation of vagal neurons using abdominal VNS in ferrets, and showed potential for controlling gastrointestinal function through this method.

SCIENTIFIC REPORTS (2021)

Article Biochemical Research Methods

ASCENT (Automated Simulations to Characterize Electrical Nerve Thresholds): A pipeline for sample-specific computational modeling of electrical stimulation of peripheral nerves

Eric D. Musselman et al.

Summary: The differences in neural anatomy across species lead to varying responses to electrical stimulation therapy, requiring different electrodes and stimulation parameters. The ASCENT pipeline offers a standardized computational modeling process for simulating electrical activation and block of nerve fibers in peripheral nerves.

PLOS COMPUTATIONAL BIOLOGY (2021)

Review Neurosciences

Selective Neuromodulation of the Vagus Nerve

Adam Fitchett et al.

Summary: Selective vagus nerve stimulation (sVNS) has the potential to reduce side effects and enhance treatment efficacy, with several key paradigms and parameters available for selection, but there is still limited understanding of the functional anatomical organization of the vagus nerve.

FRONTIERS IN NEUROSCIENCE (2021)

Article Engineering, Biomedical

Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation

Megan L. Settell et al.

JOURNAL OF NEURAL ENGINEERING (2020)

Article Multidisciplinary Sciences

Anodal block permits directional vagus nerve stimulation

Umair Ahmed et al.

Scientific Reports (2020)

Article Neurosciences

Quantified Morphology of the Cervical and Subdiaphragmatic Vagus Nerves of Human, Pig, and Rat

Nicole A. Pelot et al.

FRONTIERS IN NEUROSCIENCE (2020)

Article Engineering, Biomedical

Sources of off-target effects of vagus nerve stimulation using the helical clinical lead in domestic pigs

Evan N. Nicolai et al.

JOURNAL OF NEURAL ENGINEERING (2020)

Article Multidisciplinary Sciences

Cervical vagus nerve morphometry and vascularity in the context of nerve stimulation - A cadaveric study

Niels Hammer et al.

SCIENTIFIC REPORTS (2018)

Article Cardiac & Cardiovascular Systems

Long-term vagal stimulation for heart failure: Eighteen month results from the NEural Cardiac TherApy foR Heart Failure (NECTAR-HF) trial

Gaetano M. De Ferrari et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2017)

Article Medicine, Research & Experimental

Fast simulation and optimization tool to explore selective neural stimulation

Melissa Dali et al.

EUROPEAN JOURNAL OF TRANSLATIONAL MYOLOGY (2016)

Article Multidisciplinary Sciences

Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling

Joel P. Baumgart et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Cardiac & Cardiovascular Systems

Sympathetic nerve fibers in human cervical and thoracic vagus nerves

Atsuko Seki et al.

HEART RHYTHM (2014)

Article Cardiac & Cardiovascular Systems

Sympathetic nerve fibers and ganglia in canine cervical vagus nerves: Localization and quantitation

Patrick Onkka et al.

HEART RHYTHM (2013)

Article Engineering, Biomedical

Selectivity for Specific Cardiovascular Effects of Vagal Nerve Stimulation With a Multi-Contact Electrode Cuff

Simone C. M. A. Ordelman et al.

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (2013)

Article Engineering, Biomedical

High-resolution measurement of electrically-evoked vagus nerve activity in the anesthetized dog

Paul B. Yoo et al.

JOURNAL OF NEURAL ENGINEERING (2013)

Review Endocrinology & Metabolism

The vagus nerve and the inflammatory reflex-linking immunity and metabolism

Valentin A. Pavlov et al.

NATURE REVIEWS ENDOCRINOLOGY (2012)

Article Cardiac & Cardiovascular Systems

Vagus nerve stimulation in experimental heart failure

Hani N. Sabbah et al.

HEART FAILURE REVIEWS (2011)

Review Clinical Neurology

Overview of the Clinical Applications of Vagus Nerve Stimulation

J. P. Beekwilder et al.

JOURNAL OF CLINICAL NEUROPHYSIOLOGY (2010)

Article Neurosciences

Isoflurane Inhibits the Neurotransmitter Release Machinery

Bruce E. Herring et al.

JOURNAL OF NEUROPHYSIOLOGY (2009)

Article Engineering, Biomedical

A model of selective activation of the femoral nerve with a flat interface nerve electrode for a lower extremity neuroprosthesis

Matthew A. Schiefer et al.

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (2008)

Article Pharmacology & Pharmacy

Effect of vagus nerve stimulation on serotonergic and noradrenergic transmission

Adrienne E. Dorr et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Article Sport Sciences

Central and peripheral fatigue of the knee extensor muscles induced by electromyostimulation

R Zory et al.

INTERNATIONAL JOURNAL OF SPORTS MEDICINE (2005)

Review Behavioral Sciences

Vagal nerve stimulation: a review of its applications and potential mechanisms that mediate its clinical effects

DA Groves et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2005)

Article Neurosciences

Cellular effects of deep brain stimulation: Model-based analysis of activation and inhibition

CC McIntyre et al.

JOURNAL OF NEUROPHYSIOLOGY (2004)

Article Anesthesiology

Inhalation anaesthetics increase heart rate by decreasing cardiac vagal activity in dogs

O Picker et al.

BRITISH JOURNAL OF ANAESTHESIA (2001)

Review Clinical Neurology

Vagus nerve stimulation, side effects, and long-term safety

E Ben-Menachem

JOURNAL OF CLINICAL NEUROPHYSIOLOGY (2001)

Article Clinical Neurology

Human vagus nerve electrophysiology - A guide to vagus nerve stimulation parameters

B Koo et al.

JOURNAL OF CLINICAL NEUROPHYSIOLOGY (2001)