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CELL REPORTS (2014)
rnTOR signaling and its roles in normal and abnormal brain development
Nobuyuki Takei et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins
Joaquin N. Lugo et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation
Candi L. LaSarge et al.
Frontiers in Molecular Neuroscience (2014)
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies
Antonella Caccamo et al.
AGING CELL (2013)
Antioxidant Activity of Arctium lappa L. and Its Effect on Biochemical Parameters in Exercised Rats
Chi-Ting Horng et al.
ASIAN JOURNAL OF CHEMISTRY (2013)
Inflammation and white matter degeneration persist for years after a single traumatic brain injury
Victoria E. Johnson et al.
BRAIN (2013)
SHANK3 as an autism spectrum disorder-associated gene
Shigeo Uchino et al.
BRAIN & DEVELOPMENT (2013)
Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells
Seog-Young Kim et al.
CELLULAR SIGNALLING (2013)
Everolimus in tuberous sclerosis patients with intractable epilepsy: A treatment option?
Gert Wiegand et al.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY (2013)
Epilepsy and brain inflammation
Annamaria Vezzani et al.
EXPERIMENTAL NEUROLOGY (2013)
PGC-1α, mitochondrial dysfunction, and Huntington's disease
Ashu Johri et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial-lysosomal cross-talk
Christian Seitz et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Foxp2 Mediates Sex Differences in Ultrasonic Vocalization by Rat Pups and Directs Order of Maternal Retrieval
J. Michael Bowers et al.
JOURNAL OF NEUROSCIENCE (2013)
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
Silke Appel-Cresswell et al.
MOVEMENT DISORDERS (2013)
Striatal Parvalbuminergic Neurons Are Lost in Huntington's Disease: Implications for Dystonia
Anton Reiner et al.
MOVEMENT DISORDERS (2013)
Mutations in DEPDC5 cause familial focal epilepsy with variable foci
Leanne M. Dibbens et al.
NATURE GENETICS (2013)
Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis
Shalini Kumar et al.
NEUROBIOLOGY OF DISEASE (2013)
The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus
Hong Sun et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
FOCAL MALFORMATIONS OF CORTICAL DEVELOPMENT: NEW VISTAS FOR MOLECULAR PATHOGENESIS
K-C Lim et al.
NEUROSCIENCE (2013)
Neuroprotective Effect of Kaempferol Glycosides against Brain Injury and Neuroinflammation by Inhibiting the Activation of NF-κB and STAT3 in Transient Focal Stroke
Lu Yu et al.
PLOS ONE (2013)
Rapamycin Treatment Improves Neuron Viability in an In Vitro Model of Stroke
Lauren Fletcher et al.
PLOS ONE (2013)
Mitochondrial dysfunction and oxidative stress in Parkinson's disease
Sudhakar Raja Subramaniam et al.
PROGRESS IN NEUROBIOLOGY (2013)
A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
Liron Bar-Peled et al.
SCIENCE (2013)
Cerebral Asymmetry and Language Development: Cause, Correlate, or Consequence?
Dorothy V. M. Bishop
SCIENCE (2013)
Amino Acid Deprivation Inhibits TORC1 Through a GTPase-Activating Protein Complex for the Rag Family GTPase Gtr1
Nicolas Panchaud et al.
SCIENCE SIGNALING (2013)
Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury
Ye Xiong et al.
THYMOSINS IN HEALTH AND DISEASE II (2012)
Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism
John T. Morgan et al.
BRAIN RESEARCH (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Alzheimer culprits: Cellular crossroads and interplay
Sylvie Claeysen et al.
CELLULAR SIGNALLING (2012)
Imaging genetics of FOXP2 in dyslexia
Arndt Wilcke et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2012)
JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease
John J. O'Shea et al.
IMMUNITY (2012)
Rapamycin Preconditioning Attenuates Transient Focal Cerebral Ischemia/Reperfusion Injury in Mice
Lele Yin et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2012)
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus
Yao-Chung Chuang et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Animal models of multiple sclerosis: the good, the bad and the bottom line
Richard M. Ransohoff
NATURE NEUROSCIENCE (2012)
PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease
Ming-Chang Chiang et al.
NEUROBIOLOGY OF DISEASE (2012)
The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus
Sun Hong et al.
NEUROLOGICAL SCIENCES (2012)
Cortical myoclonus in childhood and juvenile onset Huntington's disease
Davide Rossi Sebastiano et al.
PARKINSONISM & RELATED DISORDERS (2012)
Metabolic State Determines Sensitivity to Cellular Stress in Huntington Disease: Normalization by Activation of PPARγ
Youngnam N. Jin et al.
PLOS ONE (2012)
Non-Motor Symptoms in Patients with Parkinson's Disease - Correlations with Inflammatory Cytokines in Serum
Daniel Lindqvist et al.
PLOS ONE (2012)
Suppression of leptin-induced hypothalamic JAK/STAT signalling and feeding response during pregnancy in the mouse
S. R. Ladyman et al.
REPRODUCTION (2012)
Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex
Atsushi Sato et al.
NATURE COMMUNICATIONS (2012)
Microglia in the Cerebral Cortex in Autism
Nicole A. Tetreault et al.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2012)
Phosphorylation of amyloid beta (Aβ) peptides - A trigger for formation of toxic aggregates in Alzheimer's disease
Sathish Kumar et al.
AGING-US (2011)
Inflammation after Trauma: Microglial Activation and Traumatic Brain Injury
Anil F. Ramlackhansingh et al.
ANNALS OF NEUROLOGY (2011)
Resveratrol and apoptosis
Hung-Yun Lin et al.
RESVERATROL AND HEALTH (2011)
Amyloid Precursor Protein Processing and Alzheimer's Disease
Richard J. O'Brien et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Antidepressant-like effect of pioglitazone in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway
Mohammad Salehi Sadaghiani et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Rapamycin protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats
Anjali Chauhan et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Targeting Post-translational Modifications on Tau as a Therapeutic Strategy for Alzheimer's Disease
Jacob Newman Marcus et al.
JOURNAL OF NEUROGENETICS (2011)
mTOR: from growth signal integration to cancer, diabetes and ageing
Roberto Zoncu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Activation of JAK2/STAT pathway in cerebral cortex after experimental traumatic brain injury of rats
Jin-bing Zhao et al.
NEUROSCIENCE LETTERS (2011)
Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease
Yuncheng Wu et al.
NEUROSIGNALS (2011)
Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders
Dan Ehninger et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Ginsenoside Rh1 suppresses inducible nitric oxide synthase gene expression in IFN-γ-stimulated microglia via modulation of JAK/STAT and ERK signaling pathways
Ji-Sun Jung et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
A Meta-Analysis of Cytokines in Major Depression
Yekta Dowlati et al.
BIOLOGICAL PSYCHIATRY (2010)
IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Rα in T cells
Catarina M. Henriques et al.
BLOOD (2010)
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
Fiona M. Menzies et al.
BRAIN (2010)
Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
Jeffrey J. Hutsler et al.
BRAIN RESEARCH (2010)
Genetic Etiology of Parkinson Disease Associated with Mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 Genes: A Mutation Update
Karen Nuytemans et al.
HUMAN MUTATION (2010)
Is there a role for the nuclear receptor PPARγ in neuropsychiatric diseases?
Borja Garcia-Bueno et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau EFFECTS ON COGNITIVE IMPAIRMENTS
Antonella Caccamo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway
Hye Shin Lee et al.
JOURNAL OF CELL SCIENCE (2010)
The neurovascular unit in the setting of stroke
G. J. del Zoppo
JOURNAL OF INTERNAL MEDICINE (2010)
Activation of calcium/Calmodulin-Dependent Protein Kinase IV and Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Signaling Pathway Protects Against Neuronal Injury and Promotes Mitochondrial Biogenesis in the Hippocampal CA1 Subfield After Transient Global Ischemia
Shang-Der Chen et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-beta Levels in a Mouse Model of Alzheimer's Disease
Patricia Spilman et al.
PLOS ONE (2010)
Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
Helena S. Domingues et al.
PLOS ONE (2010)
Pioglitazone ameliorates behavioral, biochemical and cellular alterations in quinolinic acid induced neurotoxicity: Possible role of peroxisome proliferator activated receptor-Γ (PPARΓ) in Huntington's disease
Harikesh Kalonia et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2010)
Th17 cells in autoimmune demyelinating disease
Benjamin Matthew Segal
SEMINARS IN IMMUNOPATHOLOGY (2010)
Differential Regulation of Proliferation and Differentiation in Neural Precursor Cells by the Jak Pathway
Yun Hee Kim et al.
STEM CELLS (2010)
Rosiglitazone Add-On in Treatment of Depressed Patients with Insulin Resistance: a Pilot Study
Natalie L. Rasgon et al.
THESCIENTIFICWORLDJOURNAL (2010)
Unravelling mononuclear phagocyte heterogeneity
Frederic Geissmann et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Antidepressant-like effects of rosiglitazone, a PPAR gamma agonist, in the rat forced swim and mouse tail suspension tests
Amany Ali Eissa Ahmed et al.
BEHAVIOURAL PHARMACOLOGY (2009)
The cortical innate immune response increases local neuronal excitability leading to seizures
Krista M. Rodgers et al.
BRAIN (2009)
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
S. Sarkar et al.
CELL DEATH AND DIFFERENTIATION (2009)
PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease
Nicoletta Schintu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Impaired PGC-1α function in muscle in Huntington's disease
Rajnish K. Chaturvedi et al.
HUMAN MOLECULAR GENETICS (2009)
Chemokines and Chemokine Receptors: Standing at the Crossroads of Immunobiology and Neurobiology
Richard M. Ransohoff
IMMUNITY (2009)
A pilot test of pioglitazone as an add-on in patients with relapsing remitting multiple sclerosis
Claudia C. Kaiser et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Somatosensory temporal discrimination in patients with primary focal dystonia
A. Scontrini et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2009)
A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules
L. Mestre et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
Innate and Adaptive Autoimmunity Directed to the Central Nervous System
Roopa Bhat et al.
NEURON (2009)
Inhibition of mTOR Signaling in Parkinson's Disease Prevents L-DOPA-Induced Dyskinesia
Emanuela Santini et al.
SCIENCE SIGNALING (2009)
Apoptotic Mechanisms After Cerebral Ischemia
Brad R. S. Broughton et al.
STROKE (2009)
Autoimmune T cell responses in the central nervous system
Joan Goverman
NATURE REVIEWS IMMUNOLOGY (2009)
Lipoxygenase-derived metabolites are regulators of peroxisome proliferator-activated receptor γ-2 expression in human vascular smooth muscle cells
Rona Limor et al.
AMERICAN JOURNAL OF HYPERTENSION (2008)
Inflammation, glutamate, and glia in depression: A literature review
Leah McNally et al.
CNS SPECTRUMS (2008)
Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism
Gilles Maussion et al.
HUMAN MOLECULAR GENETICS (2008)
Signal Transducer and Activator of Transcription 4 Is Required for the Transcription Factor T-bet to Promote T Helper 1 Cell-Fate Determination
Vivian T. Thieu et al.
IMMUNITY (2008)
SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta 1 by regulating JAK2/STAT3 signaling in pancreas
Ji Hoon Yu et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Peroxisome proliferator-activated receptor gamma agonist, rosiglitazone, suppresses CD40 expression and attenuates inflammatory responses after lithium pilocarpine-induced status epilepticus in rats
Hong Sun et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2008)
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
Tereza Vogiatzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Maria Bjorkqvist et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo
Kotaro Sasaki et al.
JOURNAL OF IMMUNOLOGY (2008)
Activation of peroxisome proliferator-activated receptor γ (PPARγ) suppresses rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes
Servio H. Ramirez et al.
JOURNAL OF IMMUNOLOGY (2008)
Identification of PSEN1 and APP gene mutations in Korean patients with early-onset Alzheimer's disease
Hyun-Kyung Park et al.
JOURNAL OF KOREAN MEDICAL SCIENCE (2008)
PPAR: a therapeutic target in Parkinson's disease
Rajnish K. Chaturvedi et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Genomic effects of once-weekly, intramuscular interferon-β1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients
Bianca Weinstock-Guttman et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
15-Deoxy-Δ12,14-prostaglandin J2 inhibits INF-γ-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells
Ulf Panzer et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2008)
Effect of cytokines on neuronal excitability
Maria Schaefers et al.
NEUROSCIENCE LETTERS (2008)
Association between PTGS2 polymorphism and autism spectrum disorders in Korean trios
Hee Jeong Yoo et al.
NEUROSCIENCE RESEARCH (2008)
Role of GSK3β in behavioral abnormalities induced by serotonin deficiency
Jean-Martin Beaulieu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
Kevin Kyungsuk Park et al.
SCIENCE (2008)
Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists
Antonietta Bernardo et al.
PPAR RESEARCH (2008)
Peroxisome proliferator-activated receptor γ up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis
Karen Fuenzalida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Psychiatric symptoms in Huntington's disease before diagnosis: The Predict-HD study
Kevin Duff et al.
BIOLOGICAL PSYCHIATRY (2007)
Contribution of SHANK3 mutations to autism spectrum disorder
Rainald Moessner et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Mitochondrial uncoupling proteins - What is their physiological role?
Karim S. Echtay
FREE RADICAL BIOLOGY AND MEDICINE (2007)
High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells
Takuya Miyagi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Brain endothelial PPAR-γ controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro
Luisa Klotz et al.
JOURNAL OF NEUROIMMUNOLOGY (2007)
Kaempferol inhibits IL-4-Induced STAT6 activation by specifically targeting JAK3
Jose R. Cortes et al.
JOURNAL OF IMMUNOLOGY (2007)
PPARs and molecular mechanisms of transrepression
Mercedes Ricote et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
JAK-STAT signaling: From interferons to cytokines
Christian Schindler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Pathogenic mutations in Parkinson disease
Eng-King Tan et al.
HUMAN MUTATION (2007)
Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats
Borja Garcia-Bueno et al.
NEUROPSYCHOPHARMACOLOGY (2007)
c-MYC activation impairs the NF-κB and the interferon response:: Implications for the pathogenesis of Burkitt's lymphoma
Martin Schlee et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Levels of serum interleukin (IL)-6, IL-1β, tumour necrosis factor-α and leptin and their correlation in depression
Kun Yang et al.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2007)
Variations in the APP gene promoter region and risk of Alzheimer disease
L. Guyant-Marechal et al.
NEUROLOGY (2007)
Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage
Jae-Hyuk Yi et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Effects of rosiglitazone on global ischemia-induced hippocampal injury and expression of mitochondrial uncoupling protein 2
Shang-Der Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells - Functional consequences
Tamara Milakovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy
Jan A. Gorter et al.
JOURNAL OF NEUROSCIENCE (2006)
Transcriptional repression of PGC-α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
Libin Cui et al.
CELL (2006)
pSTAT1, pSTAT3, and T-bet expression in peripheral blood mononuclear cells from relapsing-remitting multiple sclerosis patients correlates with disease activity
Giovanni Frisullo et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Jason S. Stumhofer et al.
NATURE IMMUNOLOGY (2006)
IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors
Sabine Chourbaji et al.
NEUROBIOLOGY OF DISEASE (2006)
JAK2 and STAT3 activation contributes to neuronal damage following transient focal cerebral ischemia
Irawan Satriotomo et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
Marcel Batten et al.
NATURE IMMUNOLOGY (2006)
Peroxisome proliferator-activated receptor agonist regulation of glial activation: Relevance to CNS inflammatory disorders
Paul D. Drew et al.
NEUROCHEMISTRY INTERNATIONAL (2006)
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
Paula M. Keeney et al.
JOURNAL OF NEUROSCIENCE (2006)
Pten regulates neuronal arborization and social interaction in mice
Chang-Hyuk Kwon et al.
NEURON (2006)
Uncoupling proteins: A role in protection against reactive oxygen species - or not?
Barbara Cannon et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
High mobility group box 1 protein interacts with multiple Toll-like receptors
JS Park et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Activation of JAK/STAT signalling in neurons following spinal cord injury in mice
K Yamauchi et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Regulation of cytokine signaling pathways by PIAS proteins
K Shuai
CELL RESEARCH (2006)
An architectural framework that may lie at the core of the postsynaptic density
MK Baron et al.
SCIENCE (2006)
Role of hypokinesia and bradykinesia in gait disturbances in Huntington's disease - A biomechanical study
A Delval et al.
JOURNAL OF NEUROLOGY (2006)
Brain inflammation in epilepsy: Experimental and clinical evidence
A Vezzani et al.
EPILEPSIA (2005)
Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor γ levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients
L Klotz et al.
JOURNAL OF IMMUNOLOGY (2005)
PPARγ antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis
HP Raikwar et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene
WG Shu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor γ activation
R Luna-Medina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family
M Funayama et al.
ANNALS OF NEUROLOGY (2005)
Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: Implications for multiple sclerosis
PD Storer et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
Hemispheric lateralization of spatial attention in right- and left-hemispheric language dominance
A Flöel et al.
BEHAVIOURAL BRAIN RESEARCH (2005)
Benefit finding in multiple sclerosis, and associations with positive and negative outcomes
KI Pakenham
HEALTH PSYCHOLOGY (2005)
Inducers of oxidative stress block ciliary neurotrophic factor activation of Jak/STAT signaling in neurons
N Kaur et al.
JOURNAL OF NEUROCHEMISTRY (2005)
A mutant PSEN1 causes dementia with Lewy bodies and variant Alzheimer's disease
A Ishikawa et al.
ANNALS OF NEUROLOGY (2005)
FOXP2 and the neuroanatomy of speech and language
F Vargha-Khadem et al.
NATURE REVIEWS NEUROSCIENCE (2005)
Anti-inflammatory and antiproliferative actions of PPAR-γ agonists on T lymphocytes derived from MS patients
S Schmidt et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation - A longitudinal follow-up study
J Lemiere et al.
JOURNAL OF NEUROLOGY (2004)
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
DD Sarbassov et al.
CURRENT BIOLOGY (2004)
Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy
B Voutsinos-Porche et al.
NEUROBIOLOGY OF DISEASE (2004)
Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy
NP Turrin et al.
NEUROBIOLOGY OF DISEASE (2004)
Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS
S Moreno et al.
NEUROSCIENCE (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
Disrupted in Schizophrenia 1 (DISC1): Association with schizophrenia, schizoaffective disorder, and bipolar disorder
CA Hodgkinson et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin
G Meyer et al.
NEUROPHARMACOLOGY (2004)
TSC2 mediates cellular energy response to control cell growth and survival
K Inoki et al.
CELL (2003)
DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism
V Bonifati et al.
NEUROLOGICAL SCIENCES (2003)
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
PC Heinrich et al.
BIOCHEMICAL JOURNAL (2003)
Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARγ) in murine primary astrocytes and neurons
L Klotz et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells
A Dimberg et al.
BLOOD (2003)
15d-PGJ2 and rosilglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia
EJ Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Inhibition of glial cell proinflammatory activities by peroxisome proliferator-activated receptor gamma agonist confers partial protection during antimyelin oligodendrocyte glycoprotein demyelination in vitro
CB Duvanel et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2003)
Peroxisome proliferator-activated receptor γ-mediated NF-κB activation and apoptosis in pre-B cells
JJ Schlezinger et al.
JOURNAL OF IMMUNOLOGY (2002)
Epileptic seizures, cranial neuralgias and paroxysmal symptoms in remitting and progressive multiple sclerosis
M Eriksson et al.
MULTIPLE SCLEROSIS (2002)
IL-2 receptor signaling through the Shb adapter protein in T and NK cells
CK Lindholm
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy
JM Morante-Redolat et al.
HUMAN MOLECULAR GENETICS (2002)
STAT6 as an asthma candidate gene:: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study
G Duetsch et al.
HUMAN MOLECULAR GENETICS (2002)
Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease
AJ Hughes et al.
NEUROLOGY (2001)
Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome
MC Bonaglia et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Phosphorylation of signal transducer and activator of transcription-3 (Stat3) after focal cerebral ischemia in rats
S Suzuki et al.
EXPERIMENTAL NEUROLOGY (2001)
Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-γ
M Niino et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
Neurodegenerative tauopathies
VMY Lee et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
TOR, a central controller of cell growth
T Schmelzle et al.
CELL (2000)
Role of the peroxisome proliferator-activated receptor-γ (PPAR-γ) and its natural ligand 15-deoxy-Δ12,14-prostaglandin J2 in the regulation of microglial functions
A Bernardo et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Independent occurrence of the CHRNA4 Ser248Phe mutation in a Norwegian family with nocturnal frontal lobe epilepsy
OK Steinlein et al.
EPILEPSIA (2000)
Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor γ (PPARγ) agonists -: PPARγ co-association with transcription factor NFAT
XY Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The nuclear receptor PPARγ and immunoregulation:: PPARγ mediates inhibition of helper T cell responses
RB Clark et al.
JOURNAL OF IMMUNOLOGY (2000)
Hypothalamic vasopressin gene expression increases in both males and females postpartum in a biparental rodent
ZX Wang et al.
JOURNAL OF NEUROENDOCRINOLOGY (2000)
Inflammatory mechanisms in Alzheimer's disease:: Inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists
CK Combs et al.
JOURNAL OF NEUROSCIENCE (2000)
Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters
A Stephanou et al.
CELL DEATH AND DIFFERENTIATION (2000)