Chiral ionic liquids synthesis and their applications in racemic drug separation and analysis

Chiral ionic liquids(CILs) have attracted much attention due to their chiral recognition, strong polarity, high thermal stability and reusability. In this paper, the classification and properties of CILs are firstly introduced, and then the synthesis methods of CILs are reviewed with synthetic source materials as the main line. Finally, the application of CILs in the separation and analysis of chiral drugs is demon-strated. The purpose of this paper is to provide readers with new research results on CILs.(c) 2022 Elsevier B.V. All rights reserved.

Automated summary

This paper firstly introduces the classification and properties of Chiral Ionic Liquids (CILs), then reviews the synthesis methods of CILs with synthetic source materials as the main focus, and finally demonstrates the application of CILs in the separation and analysis of chiral drugs. The purpose of this paper is to provide readers with new research results on CILs.