4.7 Article

Transcriptional Inhibition of MicroRNA miR-122 by Small Molecules Reduces Hepatitis C Virus Replication in Liver Cells

Related references

Note: Only part of the references are listed.
Review Endocrinology & Metabolism

Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease

Yang Xiao et al.

MOLECULAR METABOLISM (2020)

Article Biochemistry & Molecular Biology

miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5 terminus

Jasmin Chahal et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Pharmacology & Pharmacy

Daclatasvir: A Review of Preclinical and Clinical Pharmacokinetics

Yash Gandhi et al.

CLINICAL PHARMACOKINETICS (2018)

Review Pharmacology & Pharmacy

Hepatitis C virus drug resistance associated substitutions and their clinical relevance: Update 2018

Maria C. Sorbo et al.

DRUG RESISTANCE UPDATES (2018)

Article Pharmacology & Pharmacy

Ledipasvir/Sofosbuvir: A Review in Chronic Hepatitis C

Lesley J. Scott

DRUGS (2018)

Article Biochemistry & Molecular Biology

Eukaryotic translation initiation factor 4AII contributes to microRNA-122 regulation of hepatitis C virus replication

Choudhary Shoaib Ahmed et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Multidisciplinary Sciences

RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus

Rodney P. Kincaid et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Gastroenterology & Hepatology

Host-targeting therapies for hepatitis C virus infection: current developments and future applications

Emilie Crouchet et al.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2018)

Review Genetics & Heredity

Role of microRNAs in obesity and obesity-related diseases

Giuseppe Iacomino et al.

GENES AND NUTRITION (2017)

Article Microbiology

Characterization of miR-122-independent propagation of HCV

Chikako Ono et al.

PLOS PATHOGENS (2017)

Review Genetics & Heredity

Role of microRNAs in obesity and obesity-related diseases

Giuseppe Iacomino et al.

GENES AND NUTRITION (2017)

Review Cardiac & Cardiovascular Systems

Liver microRNAs: potential mediators and biomarkers for metabolic and cardiovascular disease?

Peter Willeit et al.

EUROPEAN HEART JOURNAL (2016)

Article Chemistry, Medicinal

Structure Property Relationships of Carboxylic Acid Isosteres

Pierrik Lassalas et al.

JOURNAL OF MEDICINAL CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection

Gahl Levy et al.

NATURE CHEMICAL BIOLOGY (2016)

Review Immunology

Entry inhibitors: New advances in HCV treatment

Xi-Jing Qian et al.

EMERGING MICROBES & INFECTIONS (2016)

Review Biochemistry & Molecular Biology

The role of MicroRNAs in human cancer

Yong Peng et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2016)

Review Biochemistry & Molecular Biology

Small molecule chemical probes of microRNA function

Sai Pradeep Velagapudi et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2015)

Review Chemistry, Multidisciplinary

Small molecules targeting microRNA for cancer therapy: Promises and obstacles

Di Wen et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Review Gastroenterology & Hepatology

miR-122-A key factor and therapeutic target in liver disease

Simonetta Bandiera et al.

JOURNAL OF HEPATOLOGY (2015)

Article Virology

cis-Acting RNA elements in the hepatitis C virus RNA genome

Selena M. Sagan et al.

VIRUS RESEARCH (2015)

Article Virology

How do persistent infections with hepatitis C virus cause liver cancer?

Jonathan K. Mitchell et al.

CURRENT OPINION IN VIROLOGY (2015)

Article Pharmacology & Pharmacy

Sofosbuvir: First Global Approval

Gillian M. Keating et al.

DRUGS (2014)

Review Gastroenterology & Hepatology

HCV direct-acting antiviral agents: the best interferon-free combinations

Raymond Schinazi et al.

LIVER INTERNATIONAL (2014)

Article Biochemistry & Molecular Biology

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122

Luca F. R. Gebert et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Hematology

MicroRNAs in Metabolic Disease

Carlos Fernandez-Hernando et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication

You Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter

Alice Kiselyuk et al.

CHEMISTRY & BIOLOGY (2012)

Review Oncology

Silencing disease genes in the laboratory and the clinic

Jonathan K. Watts et al.

JOURNAL OF PATHOLOGY (2012)

Article Biochemistry & Molecular Biology

Liver-specific microRNA-122 Biogenesis and function

Catherine L. Jopling

RNA BIOLOGY (2012)

Review Endocrinology & Metabolism

MicroRNA Regulation of Cholesterol Metabolism

Noemi Rotllan et al.

CHOLESTEROL (2012)

Article Biochemical Research Methods

High-Throughput Luciferase Reporter Assay for Small-Molecule Inhibitors of MicroRNA Function

Colleen M. Connelly et al.

JOURNAL OF BIOMOLECULAR SCREENING (2012)

Article Gastroenterology & Hepatology

Positive regulation of hepatic miR-122 expression by HNF4α

Zhen-Ya Li et al.

JOURNAL OF HEPATOLOGY (2011)

Article Multidisciplinary Sciences

Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex

Erica S. Machlin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Pharmacology & Pharmacy

Targeting MicroRNAs With Small Molecules: From Dream to Reality

S. Zhang et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)

Review Cardiac & Cardiovascular Systems

Role of MicroRNAs in Cardiovascular Disease: Therapeutic Challenges and Potentials

J. David Port et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2010)

Article Chemistry, Multidisciplinary

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

Douglas D. Young et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Review Cell Biology

Many roads to maturity: microRNA biogenesis pathways and their regulation

Julia Winter et al.

NATURE CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

Xiaohui Yuan et al.

PLOS ONE (2009)

Article Multidisciplinary Sciences

Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression

Douglas S. Auld et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Chemistry, Multidisciplinary

Small-molecule inhibitors of microRNA miR-21 function

Kiranmai Gumireddy et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Review Biotechnology & Applied Microbiology

Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?

A. W. Tong et al.

CANCER GENE THERAPY (2008)

Article Biochemistry & Molecular Biology

microRNA-122 stimulates translation of hepatitis C virus RNA

Jura Inga Henke et al.

EMBO JOURNAL (2008)

Article Multidisciplinary Sciences

Cellular cofactors affecting hepatitis C virus infection and replication

Glenn Randall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Cell Biology

Gene regulation by microRNAs

RW Carthew

CURRENT OPINION IN GENETICS & DEVELOPMENT (2006)

Article Biochemistry & Molecular Biology

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

TA Rand et al.

Article Multidisciplinary Sciences

Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA

CL Jopling et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

Control of pancreas and liver gene expression by HNF transcription factors

DT Odom et al.

SCIENCE (2004)

Article Biochemistry & Molecular Biology

Structural basis for HNF-4α activation by ligand and coactivator binding

K Duda et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Identification of patterns in biological sequences at the ALGGEN server:: PROMO and MALGEN

D Farré et al.

NUCLEIC ACIDS RESEARCH (2003)

Article Biochemistry & Molecular Biology

Crystal structure of the HNF4α ligand binding domain in complex with endogenous fatty acid ligand

S Dhe-Paganon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Ligand specificity and conformational dependence of the hepatic nuclear factor-4α (HNF-4α).

AD Petrescu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemical Research Methods

PROMO:: detection of known transcription regulatory elements using species-tailored searches

X Messeguer et al.

BIOINFORMATICS (2002)