3D photography is a reliable method of measuring infantile haemangioma volume over time

Background: Infantile haemangiomas are common lesions of infancy. With the development of novel treatments utilised to accelerate their regression, there is a need for a method of assessing these lesions over time. Volume is an ideal assessment method because of its quantifiable nature. This study investigated whether 3D photography is a valid tool for measuring the volume of infantile haemangiomas over time. Method: Thirteen children with infantile haemangiomas presenting to the Vascular Anomalies Clinic, Royal Children's Hospital/Lady Cilento Children's Hospital treated with propranolol were included in the study. Lesion volume was assessed using 3D photography at presentation, one month and three months follow up. Intrarater reliability was determined by retracing all images several months after the initial mapping. Interrater reliability of the 3D camera software was determined by two investigators, blinded to each other's results, independently assessing infantile haemangioma volume. Results: Lesion volume decreased significantly between presentation and three-month follow-up (p < 0.001). Volume intra-and interrater reliability were excellent with ICC 0.991 (95% CI 0.982, 0.995) and 0.978 (95% CI 0.955, 0.989), respectively. Conclusion: This study demonstrates images taken with the 3D LifeViz (TM) camera and lesion volume calculated with Dermapix (R) software is a reliable method for assessing infantile haemangioma volume over time. (C) 2016 Elsevier Inc. All rights reserved.