Related references
Note: Only part of the references are listed.Cellular senescence in the cholangiopathies
Pamela S. Bogert et al.
CURRENT OPINION IN GASTROENTEROLOGY (2022)
Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury
Jennifer K. Truong et al.
JOURNAL OF LIPID RESEARCH (2022)
Maralixibat for the treatment of PFIC: Long-term, IBAT inhibition in an open-label, Phase 2 study
Kathleen M. Loomes et al.
HEPATOLOGY COMMUNICATIONS (2022)
Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid
Jan Freark de Boer et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2021)
Microbial Hydroxysteroid Dehydrogenases: From Alpha to Omega
Heidi L. Doden et al.
MICROORGANISMS (2021)
Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis
David J. Matye et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2021)
An Overview of 7α- and 7β-Hydroxysteroid Dehydrogenases: Structure, Specificity and Practical Application
Deshuai Lou et al.
PROTEIN AND PEPTIDE LETTERS (2021)
Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis
Weihua Chen et al.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2020)
A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]
Jan Freark de Boer et al.
JOURNAL OF LIPID RESEARCH (2020)
Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition[S]
Akira Honda et al.
JOURNAL OF LIPID RESEARCH (2020)
Intestinal Microbiome-Macrophage Crosstalk Contributes to Cholestatic Liver Disease by Promoting Intestinal Permeability in Mice
Anna Isaacs-Ten et al.
HEPATOLOGY (2020)
Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study
Philip N. Newsome et al.
JOURNAL OF HEPATOLOGY (2020)
Animal models to study bile acid metabolism
Jianing Li et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
Structural and functional characterization of a novel acidophilic 7α-hydroxysteroid dehydrogenase
Shijin Tang et al.
PROTEIN SCIENCE (2019)
The gut microbial influence on cholestatic liver disease
Martin Kummen et al.
LIVER INTERNATIONAL (2019)
Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial
Gideon M. Hirschfield et al.
JOURNAL OF HEPATOLOGY (2019)
Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice
Jibiao Li et al.
TOXICOLOGICAL SCIENCES (2018)
Fibroblast Growth Factor 15-Dependent and Bile Acid-Independent Promotion of Liver Regeneration in Mice
Bo Kong et al.
HEPATOLOGY (2018)
A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis
Kris V. Kowdley et al.
HEPATOLOGY (2018)
Benefit of Adding Ezetimibe to Statin Therapy on Cardiovascular Outcomes and Safety in Patients With Versus Without Diabetes Mellitus Results From IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial)
Robert P. Giugliano et al.
CIRCULATION (2018)
GUTS AND GALL: BILE ACIDS IN REGULATION OF INTESTINAL EPITHELIAL FUNCTION IN HEALTH AND DISEASE
Peter Hegyi et al.
PHYSIOLOGICAL REVIEWS (2018)
NGM282 for Treatment of Patients With Primary Biliary Cholangitis: A Multicenter, Randomized, Double Blind Placebo Controlled Trial
Marlyn J. Mayo et al.
HEPATOLOGY COMMUNICATIONS (2018)
Engineered FGF19 Eliminates Bile Acid Toxicity and Lipotoxicity Leading to Resolution of Steatohepatitis and Fibrosis in Mice
Mei Zhou et al.
HEPATOLOGY COMMUNICATIONS (2017)
Pharmacological Inhibition of Apical Sodium-Dependent Bile Acid Transporter Changes Bile Composition and Blocks Progression of Sclerosing Cholangitis in Multidrug Resistance 2 Knockout Mice
Alexander G. Miethke et al.
HEPATOLOGY (2016)
Engineered Fibroblast Growth Factor 19 Reduces Liver Injury and Resolves Sclerosing Cholangitis in Mdr2-Deficient Mice
Mei Zhou et al.
HEPATOLOGY (2016)
Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis
Anna Baghdasaryan et al.
JOURNAL OF HEPATOLOGY (2016)
Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid
Noortje Ijssennagger et al.
JOURNAL OF HEPATOLOGY (2016)
Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans
Shogo Takahashi et al.
JOURNAL OF LIPID RESEARCH (2016)
The three-dimensional structure of Clostridium absonum 7α-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition
Deshuai Lou et al.
SCIENTIFIC REPORTS (2016)
Regulators of Gut Motility Revealed by a Gnotobiotic Model of Diet-Microbiome Interactions Related to Travel
Neelendu Dey et al.
CELL (2015)
New paradigms in the treatment of hepatic cholestasis: From UDCA to FXR, PXR and beyond
Ulrich Beuers et al.
JOURNAL OF HEPATOLOGY (2015)
Bile Acid Signaling in Metabolic Disease and Drug Therapy
Tiangang Li et al.
PHARMACOLOGICAL REVIEWS (2014)
Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
Sama I. Sayin et al.
CELL METABOLISM (2013)
Gastrointestinal transit measurements in mice with Tc-99m-DTPA-labeled activated charcoal using NanoSPECT-CT
Parasuraman Padmanabhan et al.
EJNMMI RESEARCH (2013)
Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1
Alex Odermatt et al.
BIOCHEMICAL JOURNAL (2011)
Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice
Youcai Zhang et al.
JOURNAL OF LIPID RESEARCH (2010)
Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences
Bianka Ditscheid et al.
EUROPEAN JOURNAL OF NUTRITION (2009)
Bile Acids Activate Fibroblast Growth Factor 19 Signaling in Human Hepatocytes to Inhibit Cholesterol 7 alpha-Hydroxylase Gene Expression
Kwang-Hoon Song et al.
HEPATOLOGY (2009)
Tissue distribution and ontogeny of sulfotransferase enzymes in mice
Yazen Alnouti et al.
TOXICOLOGICAL SCIENCES (2006)
OSTα-OSTβ:: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia
N Ballatori et al.
HEPATOLOGY (2005)
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
T Inagaki et al.
CELL METABOLISM (2005)
Increased fecal bile acid excretion in transgenic mice with elevated expression of human phospholipid transfer protein
SM Post et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes
ZB Duanmu et al.
DRUG METABOLISM AND DISPOSITION (2002)
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
B Goodwin et al.
MOLECULAR CELL (2000)