Development of Au@NiO decorated polypyrrole composite for non-Enzymatic electrochemical sensing of cholesterol

In this study, glassy carbon electrode modified by Au@NiO decorated polypyrrole nanocomposite (Au@NiO/PPy-GCE) was fabricated for sensing of cholesterol by non-enzymatic electrochemical method. The composite was characterized by XRD, XPS and morphological studies were examined using FE-SEM and TEM. The redox properties of cholesterol were investigated by cyclic voltammetry. When differential pulse voltammetry was employed to sense cholesterol, it exhibited a linear range from 1.0 x 10-5 to 1.0 x 10-4 M, with the sensitivity 7.6 mu A mu M-1 cm-2 and detection limit 5.8 x10-7 M. Hence, this compos-ite has excellent practical applications towards the fabrication of commercial sensors.(c) 2023 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.

Automated summary

A glassy carbon electrode modified by Au@NiO decorated polypyrrole nanocomposite (Au@NiO/PPy-GCE) was fabricated for non-enzymatic electrochemical sensing of cholesterol. The composite was characterized using XRD, XPS, FE-SEM, and TEM. Cyclic voltammetry was used to investigate the redox properties of cholesterol. Differential pulse voltammetry showed a linear range from 1.0 x 10-5 to 1.0 x 10-4 M, with a sensitivity of 7.6 mu A mu M-1 cm-2 and a detection limit of 5.8 x 10-7 M. Therefore, this composite has excellent practical applications for commercial sensors.