Related references
Note: Only part of the references are listed.Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation
Rongqing Li et al.
THERANOSTICS (2022)
Concept and application of circulating proteasomes
Won Hoon Choi et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2021)
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors
Johannes Delp et al.
ARCHIVES OF TOXICOLOGY (2021)
Beyond cells: The extracellular circulating 20S proteasomes
Vandita Dwivedi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)
Disruption of mitochondrial complex I induces progressive parkinsonism
Patricia Gonzalez-Rodriguez et al.
NATURE (2021)
New machine learning and physics-based scoring functions for drug discovery
Isabella A. Guedes et al.
SCIENTIFIC REPORTS (2021)
The molecular mechanism of LRP1 in physiological vascular homeostasis and signal transduction pathways
Zhaohui He et al.
BIOMEDICINE & PHARMACOTHERAPY (2021)
Highly accurate protein structure prediction with AlphaFold
John Jumper et al.
NATURE (2021)
STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth
Chunyan Zhang et al.
CELL METABOLISM (2020)
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods
Patrick D. McMullen et al.
TOXICOLOGY IN VITRO (2020)
Rotenone-induced reactive oxygen species signal the recruitment of STAT3 to mitochondria
Fareed Mohammed et al.
FEBS LETTERS (2020)
Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals
Wanda van der Stel et al.
ARCHIVES OF TOXICOLOGY (2020)
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
Jian-Wei Hao et al.
NATURE COMMUNICATIONS (2020)
New relevant pesticide transformation products in groundwater detected using target and suspect screening for agricultural and urban micropollutants with LC-HRMS
Karin Kiefer et al.
WATER RESEARCH (2019)
The PRIDE database and related tools and resources in 2019: improving support for quantification data
Yasset Perez-Riverol et al.
NUCLEIC ACIDS RESEARCH (2019)
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events
Neeraj Singh et al.
NEUROBIOLOGY OF DISEASE (2018)
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion
Wen Zhang et al.
Oncotarget (2018)
Development of Dihydrodibenzooxepine Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Ligands of a Novel Binding Mode as Anticancer Agents: Effective Mimicry of Chiral Structures by Olefinic E/Z-Isomers
Keisuke Yamamoto et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Single-platform multi-omic' profiling: unified mass spectrometry and computational workflows for integrative proteomics-metabolomics analysis
Benjamin C. Blum et al.
MOLECULAR OMICS (2018)
Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis
Kuo-Sheng Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
The effects of rotenone-induced toxicity via the NF-κB-iNOS pathway in rat liver
Xiaowen Jiang et al.
TOXICOLOGY MECHANISMS AND METHODS (2017)
Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions
Edik M. Blais et al.
NATURE COMMUNICATIONS (2017)
Mechanistic Investigations of the Mitochondrial Complex I Inhibitor Rotenone in the Context of Pharmacological and Safety Evaluation
Sabrina Heinz et al.
SCIENTIFIC REPORTS (2017)
The effects of rotenone-induced toxicity via the NF-κB-iNOS pathway in rat liver
Xiaowen Jiang et al.
TOXICOLOGY MECHANISMS AND METHODS (2017)
Genome-wide Analysis of STAT3-Mediated Transcription during Early Human Th17 Cell Differentiation
Subhash K. Tripathi et al.
CELL REPORTS (2017)
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease
Souvarish Sarkar et al.
NPJ PARKINSONS DISEASE (2017)
Peroxisome Proliferator-activated Receptor-gamma Inhibits the Activation of STAT3 in Cerulein-stimulated Pancreatic Acinar Cells
Kyung Don Ju et al.
JOURNAL OF CANCER PREVENTION (2017)
On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens
Amanda Shaine Janesick et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2016)
LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways
Longyu Yang et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Alterations in mitochondrial dynamics induced by tebufenpyrad and pyridaben in a dopaminergic neuronal cell culture model
Adhithiya Charli et al.
NEUROTOXICOLOGY (2016)
PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes
Li Fang et al.
PPAR RESEARCH (2016)
Pesticide exposure and risk of Alzheimer's disease: a systematic review and meta-analysis
Dandan Yan et al.
SCIENTIFIC REPORTS (2016)
Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation (Withdrawn Publication. See vol. 298, 2022)
Sivareddy Kotla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
Michal Pawlak et al.
JOURNAL OF HEPATOLOGY (2015)
The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes
Jennifer D. Sisler et al.
PLOS ONE (2015)
Toxicity, genotoxicity and proinflammatory effects of amorphous nanosilica in the human intestinal Caco-2 cell line
Adeline Tarantini et al.
TOXICOLOGY IN VITRO (2015)
Metabolome and Proteome Profiling of Complex I Deficiency Induced by Rotenone
Ina Gielisch et al.
JOURNAL OF PROTEOME RESEARCH (2015)
PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1
Juan Carlos Corona et al.
EXPERIMENTAL NEUROLOGY (2014)
Inhibition of Neuronal Cell Mitochondrial Complex I with Rotenone Increases Lipid β-Oxidation, Supporting Acetyl-Coenzyme A Levels
Andrew J. Worth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Rotenone Remarkably Attenuates Oxidative Stress, Inflammation, and Fibrosis in Chronic Obstructive Uropathy
Ying Sun et al.
MEDIATORS OF INFLAMMATION (2014)
Toward a new STATe: The role of STATs in mitochondrial function
Jeremy A. Meier et al.
SEMINARS IN IMMUNOLOGY (2014)
Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays
Nisha S. Sipes et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2013)
Signal Transducer and Activator of Transcription 3 (STAT3) Degradation by Proteasome Controls a Developmental Switch in Neurotrophin Dependence
Sachiko Murase
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
STAT1 Gene Expression Is Enhanced by Nuclear EGFR and HER2 via Cooperation With STAT3
Woody Han et al.
MOLECULAR CARCINOGENESIS (2013)
Two birds with one stone: Doing metabolomics with your proteomics kit
Roman Fischer et al.
PROTEOMICS (2013)
Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins
H. H. J. Gerets et al.
CELL BIOLOGY AND TOXICOLOGY (2012)
Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice
Lee J. Quinton et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
STAT proteins - Key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver
Bin Gao et al.
JOURNAL OF HEPATOLOGY (2012)
Evidence of the in vitro genotoxicity of methyl-pyrazole pesticides in human cells
Vanessa Graillot et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2012)
Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species
Karol Szczepanek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
NF-κB in the liver-linking injury, fibrosis and hepatocellular carcinoma
Tom Luedde et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)
Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes
Alexandra Rogue et al.
PLOS ONE (2011)
Phosphorylation-acetylation switch in the regulation of STAT1 signaling
Oliver H. Kraemer et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)
Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification
Danyel G. J. Jennen et al.
TOXICOLOGICAL SCIENCES (2010)
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Gabriela Bindea et al.
BIOINFORMATICS (2009)
LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling
Jerome Terrand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
AutoClass@IJM: a powerful tool for Bayesian classification of heterogeneous data in biology
Fiona Achcar et al.
NUCLEIC ACIDS RESEARCH (2009)
Function of Mitochondrial Stat3 in Cellular Respiration
Joanna Wegrzyn et al.
SCIENCE (2009)
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases
James P. Hardwick
BIOCHEMICAL PHARMACOLOGY (2008)
Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
Roberto Scatena et al.
PPAR RESEARCH (2008)
PPARs and molecular mechanisms of transrepression
Mercedes Ricote et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Proteasome-dependent down-regulation of activated Stat5A in the nucleus
Yuhong Chen et al.
BLOOD (2006)
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
G Pascual et al.
NATURE (2005)
Global suppression of IL-6-induced acute phase response gene expression after chronic in vivo treatment with the peroxisome proliferator-activated receptor-α activator fenofibrate
P Gervois et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Transcriptional inactivation of STAT3 by PPARγ suppresses IL-6-responsive multiple myeloma cells
LH Wang et al.
IMMUNITY (2004)
Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor γ
A Gauthier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Control of human carnitine palmitoyltransferase II gene transcription by peroxisome proliferator-activated receptor through a partially conserved peroxisome proliferator-responsive element
MJ Barrero et al.
BIOCHEMICAL JOURNAL (2003)
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene activation in the liver
T Alonzi et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)