Related references
Note: Only part of the references are listed.The versatile role of HuR in Glioblastoma and its potential as a therapeutic target for a multi-pronged attack
Abhishek Guha et al.
ADVANCED DRUG DELIVERY REVIEWS (2022)
Phase II study of ceralasertib (AZD6738) in combination with durvalumab in patients with advanced/metastatic melanoma who have failed prior anti-PD-1 therapy
R. Kim et al.
ANNALS OF ONCOLOGY (2022)
ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib
Zena Wilson et al.
CANCER RESEARCH (2022)
ATR inhibitor AZD6738 increases the sensitivity of colorectal cancer cells to 5-fluorouracil by inhibiting repair of DNA damage
Takuya Suzuki et al.
ONCOLOGY REPORTS (2022)
Dual role of ARPC1B in regulating the network between tumor-associated macrophages and tumor cells in glioblastoma
Tianqi Liu et al.
ONCOIMMUNOLOGY (2022)
Novel Immune-Related Gene-Based Signature Characterizing an Inflamed Microenvironment Predicts Prognosis and Radiotherapy Efficacy in Glioblastoma
Hang Ji et al.
FRONTIERS IN GENETICS (2022)
Harnessing radiotherapy-induced NK-cell activity by combining DNA damage-response inhibition and immune checkpoint blockade
Emmanuel C. Patin et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2022)
PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells
Zhili Wei et al.
GENES & DISEASES (2022)
Protein domain-based approaches for the identification and prioritization of therapeutically actionable cancer variants
Elisabetta Grillo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells
Zihang Chen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling
Zhenlin Wang et al.
ONCOGENE (2021)
Molecular Basis of LH Action on Breast Cancer Cell Migration and Invasion via Kinase and Scaffold Proteins
Joselina Magali Mondaca et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Phase I Study of Ceralasertib (AZD6738), a Novel DNA Damage Repair Agent, in Combination with Weekly Paclitaxel in Refractory Cancer
Seung Tae Kim et al.
CLINICAL CANCER RESEARCH (2021)
SLFN11 biomarker status predicts response to lurbinectedin as a single agent and in combination with ATR inhibition in small cell lung cancer
Kiran Kundu et al.
TRANSLATIONAL LUNG CANCER RESEARCH (2021)
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction
Jianye Xu et al.
CELL DEATH & DISEASE (2021)
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
Toshiro Hara et al.
CANCER CELL (2021)
ATR Inhibitors and Paclitaxel in Melanoma
Alan Ashworth
CLINICAL CANCER RESEARCH (2021)
The 2021 WHO Classification of Tumors of the Central Nervous System: a summary
David N. Louis et al.
NEURO-ONCOLOGY (2021)
A Comprehensive Prognostic and Immunological Analysis of a Six-Gene Signature Associated With Glycolysis and Immune Response in Uveal Melanoma
Jun Liu et al.
FRONTIERS IN IMMUNOLOGY (2021)
Driving mesenchymal transition in glioblastoma
Michael Platten
NEURO-ONCOLOGY (2020)
LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2
Hua Yu et al.
CELL DEATH AND DIFFERENTIATION (2020)
Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation
Jianye Xu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma
S. L. George et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Transfer of MicroRNA via Macrophage-Derived Extracellular Vesicles Promotes Proneural-to-Mesenchymal Transition in Glioma Stem Cells
Zongpu Zhang et al.
CANCER IMMUNOLOGY RESEARCH (2020)
ATR inhibitor AZD6738 enhances the antitumor activity of radiotherapy and immune checkpoint inhibitors by potentiating the tumor immune microenvironment in hepatocellular carcinoma
Hailong Sheng et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa
Cindy Orvain et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
HPV E7 inhibits cell pyroptosis by promoting TRIM21-mediated degradation and ubiquitination of the IFI16 inflammasome
Yinjing Song et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)
Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation
Mutsuko Minata et al.
CELL REPORTS (2019)
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
Cyril Neftel et al.
CELL (2019)
Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex
Jiyeon Choi et al.
CANCER SCIENCE (2019)
HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting
Souad Mubaid et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production
Dapei Li et al.
CELL REPORTS (2019)
The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1
Ashwin Narayanan et al.
CELL DEATH AND DIFFERENTIATION (2019)
Integrated Regulation of HuR by Translation Repression and Protein Degradation Determines Pulsatile Expression of p53 Under DNA Damage
Abhishek Guha et al.
ISCIENCE (2019)
Current Challenges and Opportunities in Treating Glioblastoma
Andrea Shergalis et al.
PHARMACOLOGICAL REVIEWS (2018)
Targeting the replication stress response in cancer
Josep V. Forment et al.
PHARMACOLOGY & THERAPEUTICS (2018)
THE Arp2/3 REGULATORY SYSTEM AND ITS DEREGULATION IN CANCER
Nicolas Molinie et al.
PHYSIOLOGICAL REVIEWS (2018)
Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
Gillian Dunphy et al.
MOLECULAR CELL (2018)
Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent
Kevin M. Foote et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton
Karineh Kazazian et al.
CANCER RESEARCH (2017)
Advances in the molecular genetics of gliomas - implications for classification and therapy
Guido Reifenberger et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
APOBEC3B and IL-6 form a positive feedback loop in hepatocellular carcinoma cells
Shuran Li et al.
SCIENCE CHINA-LIFE SCIENCES (2017)
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
Jessica F. Almine et al.
NATURE COMMUNICATIONS (2017)
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
Sophia Frentzas et al.
NATURE MEDICINE (2016)
Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
Anna Segerman et al.
CELL REPORTS (2016)
Tumour-infiltrating CD4+ and CD8+ lymphocytes as predictors of clinical outcome in glioma
S. Han et al.
BRITISH JOURNAL OF CANCER (2014)
Open Comet: An automated tool for comet assay image analysis
Benjamin M. Gyori et al.
REDOX BIOLOGY (2014)
Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
Krishna P. L. Bhat et al.
CANCER CELL (2013)
New insights into the regulation and cellular functions of the ARP2/3 complex
Jeremy D. Rotty et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
Wanjuan Yang et al.
NUCLEIC ACIDS RESEARCH (2013)
A restricted cell population propagates glioblastoma growth after chemotherapy
Jian Chen et al.
NATURE (2012)
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
Krishna P. L. Bhat et al.
GENES & DEVELOPMENT (2011)
Ubiquitin becomes ubiquitous in cancer Emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets
Dingding Shi et al.
CANCER BIOLOGY & THERAPY (2010)
In Silico Analysis of Kinase Expression Identifies WEE1 as a Gatekeeper against Mitotic Catastrophe in Glioblastoma
Shahryar E. Mir et al.
CANCER CELL (2010)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
The transcriptional network for mesenchymal transformation of brain tumours
Maria Stella Carro et al.
NATURE (2010)
Regulation of HuR by DNA Damage Response Kinases
Hyeon Ho Kim et al.
JOURNAL OF NUCLEIC ACIDS (2010)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
The ARP2/3 complex: an actin nucleator comes of age
Erin D. Goley et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Share Paper
