Immunomodulatory action of Lactococcus lactis

Fermented foods are gaining popularity due to health-promoting properties with high levels of nutrients, phyto-chemicals, bioactive compounds, and probiotic microorganisms. Due to its unique fermentation process, Lactococcus lactis plays a key role in the food business, notably in the manufacturing of dairy products. The superior biological activities of L. lactis in these functional foods include anti-inflammatory and immunomodulatory capabilities. L. lactis boosted growth performance, controlled amino acid profiles, intestinal immunology, and microbiota. Besides that, the administration of L. lactis increased the rate of infection clearance. Innate and acquired immune responses would be upregulated in both local and systemic compartments, resulting in these consequences. L. lactis is often employed in the food sector and is currently being exploited as a delivery vehicle for biological research. These bacteria are being eyed as potential candidates for biotechnological applications. With this in mind, we reviewed the immunomodulatory effects of different L. lactis strains. (c) 2022, The Society for Biotechnology, Japan. All rights reserved.

Automated summary

Fermented foods are becoming increasingly popular due to their health-promoting properties. Lactococcus lactis, with its unique fermentation process, plays a key role in the production of dairy products and exhibits beneficial biological activities, such as anti-inflammatory and immunomodulatory effects. It can enhance growth performance, regulate amino acid profiles, improve intestinal immunology and microbiota, and increase infection clearance rate. L. lactis is widely used in the food industry and is being explored for biotechnological applications. In this study, the immunomodulatory effects of different L. lactis strains were reviewed. (c) 2022, The Society for Biotechnology, Japan. All rights reserved.