Journal
JOURNAL OF BIOMATERIALS APPLICATIONS
Volume 37, Issue 7, Pages 1271-1285Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/08853282221144235
Keywords
Natural polysaccharides; methacrylation; cartilage repair; compressive behavior; tribology
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The in-vitro tribological performance of methacrylated kappa-carrageenan and gellan gum hydrogels (KA-MA and GG-MA) was evaluated under physiological conditions. Among them, GG-MA-H showed robust mechanical properties, increased wear resistance, and considerably low coefficient of friction, which suggests its potential usage as a cartilage substitute.
Natural polysaccharides have recently attracted attention as structural biomaterials to replace focal chondral defects. In the present study, in-vitro tribological performance of methacrylated kappa-carrageenan and gellan gum hydrogels (KA-MA and GG-MA) was evaluated under physiological conditions. Coefficient of friction (COF) was continuously recorded over testing whilst worn area was measured post-testing. The findings help improve our understanding of KA-MA-H and GG-MA-H tribological performance under various physiological conditions. The friction and wear performance of the hydrogels improved in bovine calf serum lubricant at lower applied loads. Adhesion was the dominant wear mechanism detected by SEM. Among the proposed hydrogels GG-MA-H found robust mechanical properties, increased wear resistance and considerably low COF, which may suggest its potential usage as a cartilage substitute.
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