4.7 Article

Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia

Related references

Note: Only part of the references are listed.
Article Immunology

Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials

Kathryn J. Wicht et al.

Summary: The study edited PfCRT mutations known to mediate high-grade PPQ resistance in Southeast Asia into GB4 parasites from Gabon and found that a single PfCRT F145I mutation can mediate moderate resistance with a substantial fitness cost, while no resistance was observed with the PfCRT G353V mutant, which also increased susceptibility to other antimalarial drugs.

JOURNAL OF INFECTIOUS DISEASES (2022)

Letter Infectious Diseases

Emergence of Plasmodium falciparum triple mutant in Cambodia

Gabriele Rossi et al.

LANCET INFECTIOUS DISEASES (2017)

Article Multidisciplinary Sciences

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

Frederic Ariey et al.

NATURE (2014)

Article Microbiology

Plasmodium falciparum pfmdr1 Amplification, Mefloquine Resistance, and Parasite Fitness

Piyanuch Preechapornkul et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)