4.7 Article

Nelumbinis Stamen Ameliorates Chronic Restraint Stress-Induced Muscle Dysfunction and Fatigue in Mice by Decreasing Serum Corticosterone Levels and Activating Sestrin2

Related references

Note: Only part of the references are listed.
Article Cell Biology

Flavonoids from Sacred Lotus Stamen Extract Slows Chronological Aging in Yeast Model by Reducing Oxidative Stress and Maintaining Cellular Metabolism

Duangjai Tungmunnithum et al.

Summary: This study investigates the antiaging potential and molecular mechanisms of sacred lotus stamen extract (LSE) by examining its effects on yeast lifespan extension, oxidative stress, and metabolism. The results show that LSE is rich in flavonoids, has high antioxidant capacity, and can delay yeast aging. It also affects central metabolism, gene expressions, and enzyme regulation. These findings suggest the potential use of lotus raw material in pharmaceutical product development.

CELLS (2022)

Article Chemistry, Applied

Identification of polyphenols from Rosa roxburghii Tratt pomace and evaluation of in vitro and in vivo antioxidant activity

Dansi Huang et al.

Summary: Rosa roxburghii Tratt pomace (RRTP) was extracted to obtain free and bound phenolic fractions, which showed dose-dependent scavenging of radicals and improved survival rates in paraquat-exposed nematodes by enhancing SOD and CAT activities. These results suggest RRTP as a good and cost-effective source of natural antioxidants.

FOOD CHEMISTRY (2022)

Review Biochemistry & Molecular Biology

The connection between the dynamic remodeling of the mitochondrial network and the regulation of muscle mass

Vaninad Romanello et al.

Summary: Maintaining the function of mitochondria in skeletal muscle requires dynamic coordination of processes controlling mitochondrial network quality, which in turn affects muscle mass and performance. Loss of muscle mass increases the risk of disease onset and premature death, with exercise being the best approach to improve mitochondrial health and slow atrophy in various diseases.

CELLULAR AND MOLECULAR LIFE SCIENCES (2021)

Review Cell Biology

Shared and distinct mechanisms of skeletal muscle atrophy: A narrative review

Dylan Wilburn et al.

Summary: Maintaining skeletal muscle mass and function involves a delicate balance between anabolism and catabolism, which can be disrupted in different pathological conditions. This paper discusses the specific intracellular signaling events that regulate muscle protein atrophy in various clinical occurrences. Each pathology has unique mechanisms that contribute to muscle loss, providing researchers and clinicians with specific targets for developing more effective medical treatments and interventions.

AGEING RESEARCH REVIEWS (2021)

Article Biochemistry & Molecular Biology

Chronic Restraint Stress-Induced Muscle Atrophy Leads to Fatigue in Mice by Inhibiting the AMPK Signaling Pathway

Zhi Wang et al.

Summary: The study aimed to simulate fatigue occurrence in a chronic restraint stress (CRS) model and reveal its dynamic processes and molecular mechanisms. Findings showed that CRS treatment led to decreased physical performance, muscle atrophy, and mitochondrial dysfunction in mice, ultimately inducing fatigue.

BIOMEDICINES (2021)

Article Medicine, General & Internal

Fatigue as the Chief Complaint

Peter Maisel et al.

Summary: Fatigue is a common reason for primary care consultations, with causes ranging from sleep disorders to psychological stress. While investigations may be needed in the presence of additional symptoms, a focus on psychoeducative and psychotherapeutic approaches is recommended to prevent overdiagnosis of somatic causes.

DEUTSCHES ARZTEBLATT INTERNATIONAL (2021)

Article Multidisciplinary Sciences

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Jessica Segales et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion

Jingxia Wu et al.

SCIENCE ADVANCES (2020)

Article Physiology

Sestrins in Physiological Stress Responses

Myungjin Kim et al.

Annual Review of Physiology (2020)

Article Food Science & Technology

Research advances in traditional and modern use of Nelumbo nucifera: phytochemicals, health promoting activities and beyond

Guilin Chen et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2019)

Review Cell Biology

AMPK: guardian of metabolism and mitochondrial homeostasis

Sebastien Herzig et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Geriatrics & Gerontology

Increased Serpina3n release into circulation during glucocorticoid-mediated muscle atrophy

Marine Gueugneau et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2018)

Review Biochemistry & Molecular Biology

Biochemical Basis of Sestrin Pnysiological Activities

Allison Ho et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Physiology

The regulation of muscle mass by endogenous glucocorticoids

Theodore P. Braun et al.

FRONTIERS IN PHYSIOLOGY (2015)

Article Endocrinology & Metabolism

Chronic Fatigue in Type 1 Diabetes: Highly Prevalent but Not Explained by Hyperglycemia or Glucose Variability

Martine M. Goedendorp et al.

DIABETES CARE (2014)

Article Plant Sciences

Systematic chemical analysis of flavonoids in the Nelumbinis stamen

Jiushi Liu et al.

PHYTOMEDICINE (2014)

Review Biochemistry & Molecular Biology

Glucocorticoid-induced skeletal muscle atrophy

O. Schakman et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)

Article Endocrinology & Metabolism

Bone and Skeletal Muscle: Neighbors With Close Ties

Douglas J. DiGirolamo et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2013)

Review Biochemistry & Molecular Biology

Mitochondria: In Sickness and in Health

Jodi Nunnari et al.

Article Biochemistry & Molecular Biology

Nrf2-ARE pathway regulates induction of Sestrin-2 expression

Bo Yeon Shin et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Neurosciences

Neural regulation of endocrine and autonomic stress responses

Yvonne M. Ulrich-Lai et al.

NATURE REVIEWS NEUROSCIENCE (2009)

Article Biochemistry & Molecular Biology

p53 target genes Sestrin1 and Sestrin2 connect genotoxic stress and mTOR signaling

Andrei V. Budanov et al.

Article Physiology

Causes of excitation-induced muscle cell damage in isometric contractions: mechanical stress or calcium overload?

Anne Fredsted et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)

Review Nutrition & Dietetics

The underappreciated role of muscle in health and disease

Robert R. Wolfe

AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)

Article Behavioral Sciences

Social factors and individual vulnerability to chronic stress exposure

A Bartolomucci et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2005)

Article Neurosciences

Lactate and force production in skeletal muscle

M Kristensen et al.

JOURNAL OF PHYSIOLOGY-LONDON (2005)

Article Physiology

Weight loss in rats exposed to repeated acute restraint stress is independent of energy or leptin status

RBS Harris et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2002)