Sequential, Multiple Assignment, Randomized Trial Designs

This JAMA Guide to Statistics and Methods explains sequential, multiple assignment, randomized trial (SMART) study designs, in which some or all participants are randomized at 2 or more decision points depending on the participant's response to prior treatment.

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This article explains sequential, multiple assignment, randomized trial (SMART) study designs, where participants are randomized at 2 or more decision points depending on their response to prior treatment.