Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates

Neonates born prematurely (<37 weeks of gestation) are at a significantly increased risk of developing inflammatory conditions associated with high mortality rates, including necrotizing enterocolitis, bronchopulmonary dysplasia, and hypoxic-ischemic brain damage. Recently, research has focused on characterizing the content of extracellular vesicles (EVs), particularly microRNAs (miRNAs), for diagnostic use. Here, we describe the most recent work on EVs-miRNAs biomarkers discovery for conditions that commonly affect premature neonates.

Automated summary

Premature neonates are at an increased risk of developing inflammatory conditions with high mortality rates. Research has focused on identifying diagnostic biomarkers, such as microRNAs, in extracellular vesicles. This article discusses the latest findings in biomarker discovery for common conditions affecting premature neonates.