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Zhaohui Feng
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
MicroRNAs miR-146a/b negatively modulate the senescence associated inflammatory mediators IL-6 and IL-8
Dipa Bhaumik et al.
AGING-US (2009)
Heat Shock Protein 27 Protects Against Atherogenesis via an Estrogen-Dependent Mechanism Role of Selective Estrogen Receptor Beta Modulation
Katey Rayner et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
MiR-34, SIRT1 and p53 The feedback loop
Munekazu Yamakuchi et al.
CELL CYCLE (2009)
ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles
Vandhana Muralidharan-Chari et al.
CURRENT BIOLOGY (2009)
Exosomes - vesicular carriers for intercellular communication
Mikael Simons et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
The regulation of the endosomal compartment by p53 the tumor suppressor gene
Xin Yu et al.
FEBS JOURNAL (2009)
Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease
Jennifer L. Wacker et al.
JOURNAL OF NEUROSCIENCE (2009)
Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
Stefania Bruno et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
Stephen Tam et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Multivesicular Endosome Biogenesis in the Absence of ESCRTs
Susanne Stuffers et al.
TRAFFIC (2009)
Alzheimer's disease
Alistair Burns et al.
BMJ-BRITISH MEDICAL JOURNAL (2009)
Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice
A. Lespagnol et al.
CELL DEATH AND DIFFERENTIATION (2008)
Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
Robyn A. Sharples et al.
FASEB JOURNAL (2008)
Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation
Kohei Yuyama et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Serum cystatin C and the risk of Alzheimer disease in elderly men
J. Sundelof et al.
NEUROLOGY (2008)
Adapting proteostasis for disease intervention
William E. Balch et al.
SCIENCE (2008)
Polyglutarnine neurodegeneration: protein misfolding revisited
Aislinn J. Williams et al.
TRENDS IN NEUROSCIENCES (2008)
Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid
Laura J. Vella et al.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2008)
The role of exosomes in the processing of proteins associated with neurodegenerative diseases
Laura J. Vella et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2008)
ESCRTing proteins in the endocytic pathway
Surai Saksena et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Nonclassical IL-1β secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
Yan Qu et al.
JOURNAL OF IMMUNOLOGY (2007)
Neuroprotective role of the innate immune system by microglia
I. Glezer et al.
NEUROSCIENCE (2007)
Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies
Valerie Vingtdeux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Molecular chaperones: Multiple functions, pathologies, and potential applications
Alberto J. L. Macario et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Small heat shock proteins protect against α-synuclein-induced toxicity and aggregation
Tiago Fleming Outeiro et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions
Stephen Tam et al.
NATURE CELL BIOLOGY (2006)
Protein homeostasis and molecular chaperones in aging
Mehmet Alper Arslan et al.
BIOGERONTOLOGY (2006)
Alzheimer's disease β-amyloid peptides are released in association with exosomes
Lawrence Rajendran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The regulation of exosome secretion: a novel function of the p53 protein
Xin Yu et al.
CANCER RESEARCH (2006)
Progressive disruption of cellular protein folding in models of polyglutamine diseases
T Gidalevitz et al.
SCIENCE (2006)
Convergence of heat shock protein 90 with ubiquitin in filamentous α-synuclein inclusions of α-synucleinopathies
K Uryu et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44
A Stoeck et al.
BIOCHEMICAL JOURNAL (2006)
Chaperone-related immune dysfunction:: an emergent property of distorted chaperone networks
G Nardai et al.
TRENDS IN IMMUNOLOGY (2006)
Stressing out the EIR: A role of the unfolded protein response in prion-related disorders
CA Hetz et al.
CURRENT MOLECULAR MEDICINE (2006)
Role of molecular chaperones in neurodegenerative disorders
AB Meriin et al.
INTERNATIONAL JOURNAL OF HYPERTHERMIA (2005)
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
ML Block et al.
PROGRESS IN NEUROBIOLOGY (2005)
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis
SH Kim et al.
JOURNAL OF IMMUNOLOGY (2005)
Neurodegenerative diseases: An overview of environmental risk factors
RC Brown et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2005)
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival
H Shimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
MS Forman et al.
NATURE MEDICINE (2004)
Characterization of the hsp70 response in lymphoblasts from aged and centenarian subjects and differential effects of in vitro zinc supplementation
R Ambra et al.
EXPERIMENTAL GERONTOLOGY (2004)
Interaction of the molecular chaperone αB-crystallin with α-synuclein:: Effects on amyloid fibril formation and chaperone activity
A Rekas et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer
JL Wacker et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Cells release prions in association with exosomes
B Fevrier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The heat-shock protein receptors: some answers and more questions
RJ Binder et al.
TISSUE ANTIGENS (2004)
Role of heat shock proteins during polyglutamine neurodegeneration - Mechanisms and hypothesis
A Wyttenbach
JOURNAL OF MOLECULAR NEUROSCIENCE (2004)
Molecular chaperones, evolution and medicine
P Csermely et al.
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM (2003)
Idiopathic Parkinson's disease:: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
H Braak et al.
JOURNAL OF NEURAL TRANSMISSION (2003)
Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells
W Yang et al.
HUMAN MOLECULAR GENETICS (2002)
Cancer and aging: a model for the cancer promoting effects of the aging stroma
A Krtolica et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Chaperone function and chaperone overload in the aged.: A preliminary analysis
G Nardai et al.
EXPERIMENTAL GERONTOLOGY (2002)
Protein folding - Molecular chaperones in the cytosol: from nascent chain to folded protein
FU Hartl et al.
SCIENCE (2002)
Chaperonin-mediated de novo generation of prion protein aggregates
J Stöckel et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Prominent stress response of Purkinje cells in Creutzfeldt-Jakob disease
GG Kovács et al.
NEUROBIOLOGY OF DISEASE (2001)
Transport of human immunodeficiency virus type 1 pseudoviruses across the blood-brain barrier: Role of envelope proteins and adsorptive endocytosis
WA Banks et al.
JOURNAL OF VIROLOGY (2001)
Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
MY Sherman et al.
NEURON (2001)
Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease
J Carmichael et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Molecular chaperones and the aging process
C Soti et al.
BIOGERONTOLOGY (2000)