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Mitochondrial Transplantation in Mitochondrial Medicine: Current Challenges and Future Perspectives

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

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INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)

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Mitochondrial transplantation prolongs cold ischemia time in murine heart transplantation

Kamila Moskowitzova et al.

JOURNAL OF HEART AND LUNG TRANSPLANTATION (2019)

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Forms of extracellular mitochondria and their impact in health

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MITOCHONDRION (2019)

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The secret messages between mitochondria and nucleus in muscle cell biology

Roman Barbara Soledad et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)

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A STING to inflammation and autoimmunity

Vijay Kumar

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Primary allogeneic mitochondrial mix (PAMM) transfer/transplant by MitoCeption to address damage in PBMCs caused by ultraviolet radiation

Francisco Cabrera et al.

BMC BIOTECHNOLOGY (2019)

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Mitochondrial dynamics and their potential as a therapeutic target

B. N. Whitley et al.

MITOCHONDRION (2019)

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Mitochondrial transplantation attenuates lipopolysaccharide-induced depression-like behaviors

Yun Wang et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2019)

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Fractionated mitochondrial magnetic separation for isolation of synaptic mitochondria from brain tissue

W. Brad Hubbard et al.

SCIENTIFIC REPORTS (2019)

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Current progress of mitochondrial transplantation that promotes neuronal regeneration

Chu-Yuan Chang et al.

TRANSLATIONAL NEURODEGENERATION (2019)

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Inception Mechanisms of Tunneling Nanotubes

Mitja Drab et al.

CELLS (2019)

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Mitochondrial Transfer Ameliorates Cognitive Deficits, Neuronal Loss, and Gliosis in Alzheimer's Disease Mice

Keren Nitzan et al.

JOURNAL OF ALZHEIMERS DISEASE (2019)

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Muscle-derived autologous mitochondrial transplantation: A novel strategy for treating cerebral ischemic injury

Zhanqin Zhang et al.

BEHAVIOURAL BRAIN RESEARCH (2019)

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Genomic Balance: Two Genomes Establishing Synchrony to Modulate Cellular Fate and Function

Justin C. St John

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Circulating mitochondria in organ donors promote allograft rejection

Liwen Lin et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2019)

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The sensing of mitochondrial DAMPs by non-immune cells

Aida Rodriguez-Nuevo et al.

CELL STRESS (2019)

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A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy

Borami Shin et al.

JACC-BASIC TO TRANSLATIONAL SCIENCE (2019)

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Healthy mitochondria inhibit the metastatic melanoma in lungs

Ailing Fu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)

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Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder

Odile Robicsek et al.

SCHIZOPHRENIA BULLETIN (2018)

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Intercellular mitochondria trafficking highlighting the dual role of mesenchymal stem cells as both sensors and rescuers of tissue injury

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CELL CYCLE (2018)

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Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency

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Effects of Mitochondrial Transplantation on Bioenergetics, Cellular Incorporation, and Functional Recovery after Spinal Cord Injury

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Mitochondrial medicine in the omics era

Joyeeta Rahman et al.

LANCET (2018)

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Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases

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MITOCHONDRION (2018)

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Shedding light on the cell biology of extracellular vesicles

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Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium

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Treatment of acetaminophen-induced liver injury swith exogenous mitochondria in mice

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Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis

Jing Shen et al.

CELL DEATH & DISEASE (2018)

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Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function

Mi Jin Kim et al.

SCIENTIFIC REPORTS (2018)

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Stem cell-derived mitochondria transplantation: a novel strategy and the challenges for the treatment of tissue injury

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Tunneling nanotubes: intimate Communication between Myeloid Cells

Maeva Dupont et al.

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Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells

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SYBR Gold dye enables preferential labelling of mitochondrial nucleoids and their time-lapse imaging by structured illumination microscopy

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PLOS ONE (2018)

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Mitochondrial genetic medicine

Douglas C. Wallace

NATURE GENETICS (2018)

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Helical organization of microtubules occurs in a minority of tunneling membrane nanotubes in normal and cancer urothelial cells

Natasa Resnik et al.

SCIENTIFIC REPORTS (2018)

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Circulating mitochondria in deceased organ donors are associated with immune activation and early allograft dysfunction

Justin Pollara et al.

JCI INSIGHT (2018)

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Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury

Sitaram M. Emani et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2017)

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Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion

Aditya K. Kaza et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2017)

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Mitochondrial transplantation: From animal models to clinical use in humans

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MITOCHONDRION (2017)

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Intravenous administration of mitochondria for treating experimental Parkinson's disease

Xianxun Shi et al.

MITOCHONDRION (2017)

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Therapies for mitochondrial diseases and current clinical trials

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MOLECULAR GENETICS AND METABOLISM (2017)

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Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy

Marie-Luce Vignais et al.

STEM CELLS INTERNATIONAL (2017)

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Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications

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STEM CELLS INTERNATIONAL (2017)

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Mitotherapy for Fatty Liver by Intravenous Administration of Exogenous Mitochondria in Male Mice

Ailing Fu et al.

FRONTIERS IN PHARMACOLOGY (2017)

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Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation

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SCIENTIFIC REPORTS (2017)

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Transit and integration of extracellular mitochondria in human heart cells

Douglas B. Cowan et al.

SCIENTIFIC REPORTS (2017)

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The Origin and Diversification of Mitochondria

Andrew J. Roger et al.

CURRENT BIOLOGY (2017)

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MIRO GTPases in Mitochondrial Transport, Homeostasis and Pathology

Bor Luen Tang

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Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells

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Transferring Xenogenic Mitochondria Provides Neural Protection Against Ischemic Stress in Ischemic Rat Brains

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Extracellular vesicles: masters of intercellular communication and potential clinical interventions

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Transfer of mitochondria from astrocytes to neurons after stroke

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Astrocyte power fuels neurons during stroke

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SWISS MEDICAL WEEKLY (2016)

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Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity

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Characterization of intercellular communication and mitochondrial donation by mesenchymal stromal cells derived from the human lung

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Mitochondrial Transplantation Attenuates Airway Hyperresponsiveness by Inhibition of Cholinergic Hyperactivity

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Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection

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Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial Transfer

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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2016)

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Stem Cell-Derived Extracellular Vesicles and Immune-Modulation

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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2016)

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Horizontal transfer of RNA and proteins between cells by extracellular microvesicles: 14 years later

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Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing

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Massively parallel delivery of large cargo into mammalian cells with light pulses

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Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

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MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function

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Mitochondrial dynamics and mitochondrial quality control

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A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

Ayumu Sugiura et al.

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Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia-reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer

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Transcellular degradation of axonal mitochondria

Chung-ha O. Davis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

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Astrocytes eyeball axonal mitochondria

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The Challenges of Mitochondrial Replacement

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Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury

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AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)

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Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

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MOLECULAR BIOLOGY OF THE CELL (2013)

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Functional Recovery of Human Cells Harbouring the Mitochondrial DNA Mutation MERRF A8344G via Peptide-Mediated Mitochondrial Delivery

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Membrane nanotubes: Novel communication between distant cells

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ISOLATED MITOCHONDRIA INFUSION MITIGATES ISCHEMIA-REPERFUSION INJURY OF THE LIVER IN RATS

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SHOCK (2013)

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Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury

Mohammad Naimul Islam et al.

NATURE MEDICINE (2012)

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Minimizing the damage: repair pathways keep mitochondrial DNA intact

Lawrence Kazak et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

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Intercellular Communication by Exchange of Cytoplasmic Material via Tunneling Nano-Tube Like Structures in Primary Human Renal Epithelial Cells

Sophie Domhan et al.

PLOS ONE (2011)

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Isolation of mitochondria for biogenetical studies: An update

Erika Fernandez-Vizarra et al.

MITOCHONDRION (2010)

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Injection of isolated mitochondria during early reperfusion for cardioprotection

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AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)

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Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): Formation of mitoptotic bodies and extrusion of mitochondrial material from the cell

Konstantin G. Lyamzaev et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)

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A mitochondrial protein compendium elucidates complex I disease biology

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Mitochondria in Neuroplasticity and Neurological Disorders

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NEURON (2008)

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The layered structure of human mitochondrial DNA nucleoids

Daniel F. Bogenhagen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

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Mitochondria frozen with trehalose retain a number of biological functions and preserve outer membrane integrity

R. Yamaguchi et al.

CELL DEATH AND DIFFERENTIATION (2007)

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Neutral mitochondrial heteroplasmy alters physiological function in mice

B. M. Acton et al.

BIOLOGY OF REPRODUCTION (2007)

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Mitochondria: Dynamic organelles in disease, aging, and development

David C. Chan

CELL (2006)

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Cryopreservation of brain mitochondria: A novel methodology for functional studies

VN Nukala et al.

JOURNAL OF NEUROSCIENCE METHODS (2006)

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Mitochondrial transfer between cells can rescue aerobic respiration

JL Spees et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

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Nanotubular highways for intercellular organelle transport

A Rustom et al.

SCIENCE (2004)

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BRAIN (2004)

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