Related references
Note: Only part of the references are listed.Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk
Rick A. C. M. Boonen et al.
CANCER RESEARCH (2022)
Germline pathogenic variants in cancer risk genes among patients with thyroid cancer and suspected predisposition
Junne Kamihara et al.
CANCER MEDICINE (2022)
The Mutational Landscape of Early-Onset Breast Cancer: A Next-Generation Sequencing Analysis
Angeliki Andrikopoulou et al.
FRONTIERS IN ONCOLOGY (2022)
CHEK2 mutations and papillary thyroid cancer: correlation or coincidence?
Kortbeek Koen et al.
HEREDITARY CANCER IN CLINICAL PRACTICE (2022)
Skin cancer risk in CHEK2 mutation carriers
A. N. Bui et al.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2021)
Comprehensive germline-genomic and clinical profiling in 160 unselected children and adolescents with cancer
Rabea Wagener et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2021)
Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing
Scott Newman et al.
CANCER DISCOVERY (2021)
The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets
Cornelis M. van Tilburg et al.
CANCER DISCOVERY (2021)
Investigation of monogenic causes of familial breast cancer: data from the BEACCON case-control study
Na Li et al.
NPJ BREAST CANCER (2021)
Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variant
Alexandre Bazinet et al.
COLD SPRING HARBOR MOLECULAR CASE STUDIES (2021)
Common clonal origin of chronic myelomonocytic leukemia and B-cell acute lymphoblastic leukemia in a patient with a germline CHEK2 variant
Alexandre Bazinet et al.
COLD SPRING HARBOR MOLECULAR CASE STUDIES (2021)
Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors
Elise M. Fiala et al.
NATURE CANCER (2021)
Clinical utility of hereditary cancer panel testing: Impact of PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D results on patient management and adherence to provider recommendations
Valentina Vysotskaia et al.
CANCER (2020)
Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors
Sara Akhavanfard et al.
NATURE COMMUNICATIONS (2020)
Differences in cancer prevalence among CHEK2 carriers identified via multi-gene panel testing
Erin G. Sutcliffe et al.
CANCER GENETICS (2020)
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer
Marie Wong et al.
NATURE MEDICINE (2020)
Prevalence of Recurrent Mutations Predisposing to Breast Cancer in Early-Onset Breast Cancer Patients from Poland
Emilia Rogoza-Janiszewska et al.
CANCERS (2020)
Nationwide germline whole genome sequencing of 198 consecutive pediatric cancer patients reveals a high frequency of cancer prone syndromes
Anna Byrjalsen et al.
PLOS GENETICS (2020)
CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate
Lenka Stolarova et al.
CELLS (2020)
Homozygosity for CHEK2 p.Gly167Arg leads to a unique cancer syndrome with multiple complex chromosomal translocations in peripheral blood karyotype
Tamar Paperna et al.
JOURNAL OF MEDICAL GENETICS (2020)
Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer
Petra Kleiblova et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Germline mutations and new copy number variants among 40 pediatric cancer patients suspected for genetic predisposition
Antonella Gambale et al.
CLINICAL GENETICS (2019)
Genetic predisposition in children with cancer - affected families' acceptance of Trio-WES
Triantafyllia Brozou et al.
EUROPEAN JOURNAL OF PEDIATRICS (2018)
High Yield of Pathogenic Germline Mutations Causative or Likely Causative of the Cancer Phenotype in Selected Children with Cancer
Illja J. Diets et al.
CLINICAL CANCER RESEARCH (2018)
The landscape of genomic alterations across childhood cancers
Susanne N. Groebner et al.
NATURE (2018)
Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer
Jan Hauke et al.
CANCER MEDICINE (2018)
Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks
Brennan Decker et al.
JOURNAL OF MEDICAL GENETICS (2017)
Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors
D. Williams Parsons et al.
JAMA ONCOLOGY (2016)
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
Sue Richards et al.
GENETICS IN MEDICINE (2015)
Germline Mutations in Predisposition Genes in Pediatric Cancer
Jinghui Zhang et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
The risk of gastric cancer in carriers of CHEK2 mutations
Urszula Teodorczyk et al.
FAMILIAL CANCER (2013)
CHEK2*1100delC and Risk of Malignant Melanoma: Danish and German Studies and Meta-Analysis
Maren Weischer et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Functional characterization connects individual patient mutations in ataxia telangiectasia mutated (ATM) with dysfunction of specific DNA double-strand break-repair signaling pathways
Marlen Keimling et al.
FASEB JOURNAL (2011)
Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence
Ben Zhang et al.
LANCET ONCOLOGY (2011)
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts
Daphne W. Bell et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Rare germ line CHEK2 variants identified in breast cancer families encode proteins that show impaired activation
Nayanta Sodha et al.
CANCER RESEARCH (2006)
Childhood cancer in families with and without BRCA1 or BRCA2 mutations ascertained at a high-risk breast cancer clinic
Gabriel A. Brooks et al.
CANCER BIOLOGY & THERAPY (2006)
Characterization of CHEK2 mutations in prostate cancer
Xianglin Wu et al.
HUMAN MUTATION (2006)
CHEK2 is a multiorgan cancer susceptibility gene
C Cybulski et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Mutations in CHEK2 associated with prostate cancer risk
XY Dong et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
J Falck et al.
NATURE (2001)
Characterization of turner-associated Chk2 mutations
XL Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)