4.7 Review

Rheological insight of polysaccharide/protein based hydrogels in recent food and biomedical fields: A review

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FOOD HYDROCOLLOIDS (2022)

Article Engineering, Chemical

Role of dietary fiber and flaxseed oil in altering the physicochemical properties and 3D printability of cod protein composite gel

Yisha Xie et al.

Summary: 3D printing technology is utilized to produce personalized food for consumers with special needs. This study investigates the rheological properties of cod protein composite gel (CPCG) made with different mixes of inulin/soybean dietary fiber (IN/SDF) and flaxseed oil. The suitability of 3D printed CPCG is examined through water distribution and micro-structure analysis. The results show that CPCG with IN:SDF ratios of 7:3 and 5:5, along with 10% flaxseed oil, is highly thixotropic and suitable as food ink for 3D printing. The addition of IN/SDF and flaxseed oil decreases water molecule mobility in CPCG.

JOURNAL OF FOOD ENGINEERING (2022)

Article Biotechnology & Applied Microbiology

Advances in xanthan gum production, modifications and its applications

Iqra Mohiuddin Bhat et al.

Summary: Xanthan gum, a microbial exopolysaccharide produced by Xanthomonas campestris, is a versatile industrial biopolymer with wide applications in food, medical, textile and oil industries. It acts as a stabilizer, gelling agent, emulsifier and thickening agent, and can be modified to enhance its properties for drug delivery, tissue engineering and oil recovery.

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY (2022)

Article Materials Science, Biomaterials

Adaptive injectable carboxymethyl cellulose/poly (γ-glutamic acid) hydrogels promote wound healing

Wenjie Zhang et al.

Summary: In this study, a novel directly injectable hydrogel with high self-adaptability was designed for skin autogenous healing. The hydrogel demonstrated adequate mechanical strength, anti-fatigue abilities, rapid self-healing, biocompatibility, and proliferation-promoting activity.

BIOMATERIALS ADVANCES (2022)

Article Polymer Science

Effect of NaCl on the Rheological, Structural, and Gelling Properties of Walnut Protein Isolate-κ-Carrageenan Composite Gels

Yuqing Lei et al.

Summary: In this study, a certain concentration of Na+ was found to significantly improve the properties and texture of the walnut protein isolate-kappa-carrageenan composite gel, providing technical support for the high-value utilization and quality control of walnut protein.
Article Chemistry, Applied

Gelation behaviors of the konjac gum from different origins: A.guripingensis and A.rivirei

Qing Huang et al.

Summary: Thermal irreversible gel is an important application form of konjac gum in the food industry. Gelation behaviors of konjac gum from different sources, A.guripingensis and A.rivirei, were compared, with AGG showing better gel-forming ability than ARG. Factors influencing gel properties include konjac gum concentration, alkali content, and temperature.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Designation and characterization of cold-set whey protein-gellan gum hydrogel for iron entrapment

Zahra Kazemi-Taskooh et al.

Summary: Increasing total polymer concentration led to a more complex release mechanism, while a lower WPI/gellan ratio resulted in faster release. Iron release varied in different mediums, but followed a chemically-controlled mechanism in all samples.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Insights into the relationship between structure and rheological properties of starch gels in hot-extrusion 3D printing

Xixi Zeng et al.

Summary: This study systematically investigated the impact of structural changes in starch at different concentrations and printing temperatures on 3D printability, finding that a compact and stable gel network structure enhances printing performance. RS samples displayed higher mechanical strength compared to CS samples, with the formation of a new crystal structure, making them more suitable for printing purposes.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

The impact of model rigid fillers in acid-induced sodium caseinate/xanthan gum cooperative protein gels

Andrew J. Gravelle et al.

Summary: This study evaluates the impact of model rigid fillers on the deformation and fracture behavior of biopolymer gels and finds that filler size and surface chemistry have a significant effect on their mechanical properties, influencing the elastic modulus and fracture strain of the gels.

FOOD HYDROCOLLOIDS (2021)

Article Food Science & Technology

The effect of a variable initial pH on the structure and rheological properties of whey protein and monosaccharide gelation via the Maillard reaction

Wen-qiong Wang et al.

Summary: The study found that varying the initial pH affected the Maillard reaction-induced whey protein gel formation, structure, and rheological properties. Decreased amino and surface sulphydryl groups contributed to gel network formation. Gels formed under different pH conditions exhibited varying elastic modulus and structures.

INTERNATIONAL DAIRY JOURNAL (2021)

Article Food Science & Technology

The effects of casein and whey proteins on the rheological properties of calcium-induced skim milk gels

L. Lin et al.

Summary: The study determined the interactive effects of casein, whey proteins, and calcium ions on the rheological properties of calcium-induced skim milk gels. It was found that the final gel strength depended on the concentration of added calcium chloride, the ratio of casein to whey proteins, and whether the whey proteins were denatured by preheat treatment. Denatured whey proteins in preheated skim milk blends appeared to have two competing effects on gel strength.

INTERNATIONAL DAIRY JOURNAL (2021)

Article Biochemical Research Methods

Determination of Microstructural Impact on the Release of Drug from Hydroxypropyl Cellulose Gel by Validated In Vitro Release Test Method

Sharda Gurram et al.

Summary: The microstructure of a semisolid system greatly influences drug release properties. This study focuses on the impact of hydroxypropyl cellulose gel microstructure on the release properties of chlorhexidine gluconate (CHX G), using rheology and texture analysis. The drug release results showed significant differences in release rates between different formulations, and these differences were well correlated with rheology and texture analysis data.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2021)

Article Materials Science, Paper & Wood

Modulation of morphology, water uptake/retention, and rheological properties by in-situ modification of bacterial cellulose with the addition of biopolymers

Peddapapannagari Kalyani et al.

Summary: In situ modification of bacterial cellulose (BC) by adding agar and chitosan to the culture media leads to structural and morphological tuning, affecting water absorption/retention and rheological behavior. Agar-modified BC shows reduced pore volume and denser network with lower water absorption, while Chitosan-BC exhibits lower pore volume and reduced swellability with lower water retention. The viscoelastic deformation mechanism and water absorption behavior are discussed with respect to pore shape-size distribution and fiber dimension.

CELLULOSE (2021)

Article Chemistry, Applied

Effect of pH and mixing ratio on interpolymer complexation of scallop (Patinopecten yessoensis) male gonad hydrolysates and κ-carrageenan

Jia-Nan Yan et al.

Summary: The study found that the electrostatic complex coacervation between scallop Patinopecten. yessoensis male gonad hydrolysates and kappa-carrageenan is influenced by the ratio and pH value under different conditions. Higher gel strength is observed at lower pH values and higher ratios, forming a more evenly distributed network structure, supporting stronger gel rigidity and water-holding capacity.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Rheological characterization of polysaccharide thickeners oriented for dysphagia management: Carboxymethylated curdlan, konjac glucomannan and their mixtures compared to xanthan gum

Yuanyuan Wei et al.

Summary: Novel naturally sourced thickeners from food biopolymers have gained increasing attention in food areas, especially where edible safety of thickeners is crucial. The rheological behaviors of carboxymethylated curdlan and konjac glucomannan as potential thickeners for dysphagia were studied, showing unique viscosity enhancement abilities. However, a viscosity-lowering phenomenon was observed in konjac glucomannan solutions in the presence of maltodextrin, providing an advantage for incorporating more dietary fibers in dysphagia diets.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Effect of structuring emulsion gels by whey or soy protein isolate on the structure, mechanical properties, and in-vitro digestion of alginate-based emulsion gel beads

Duanquan Lin et al.

Summary: In this study, whey protein isolate and soy protein isolate were utilized as emulsifiers and structure-modifying agents in alginate-based emulsion gel beads. Whey protein isolate exhibited superior emulsifying properties compared to soy protein isolate, leading to smaller and more uniform droplet size distribution in the emulsions. The findings highlight the importance of using naturally occurring polymers to structure emulsion gels for controlled release of encapsulated compounds.

FOOD HYDROCOLLOIDS (2021)

Article Food Science & Technology

Influence of hydrocolloids on the rheological and textural attributes of a gluten-free meat analog based on soy protein isolate

Phawinee Nanta et al.

Summary: This study found that adding different hydrocolloids can increase the viscosity and plasticity of the meat analog, with blends of 6% C + 1% X and 6% G + 1% X showing the most potential as gluten substitutes. Hardness and gumminess are influenced by the type and concentration of hydrocolloids added.

JOURNAL OF FOOD PROCESSING AND PRESERVATION (2021)

Review Polymer Science

Functional role of crosslinking in alginate scaffold for drug delivery and tissue engineering: A review

Lisette Aguero et al.

Summary: The use of alginate polysaccharides in drug delivery and tissue engineering is on the rise due to their attractive properties. This review emphasizes the crucial role of crosslinking process in scaffold design, highlighting the potential to create biomimetic alginate hydrogels through different types of crosslinking. The possibility to enhance alginate mechanical properties through chemical modification and the importance of degradation process and biocompatibility in these applications are also discussed in detail.

EUROPEAN POLYMER JOURNAL (2021)

Article Chemistry, Applied

Rheological and textural properties of acid-induced soybean protein isolate gel in the presence of soybean protein isolate hydrolysates or their glycosylated products

Lin Li et al.

Summary: The research showed that incorporating SPI hydrolysates reduced the elastic modulus and hardness of SPI gel, especially with lower molecular weight hydrolysates. Glycosylation partially mitigated the adverse effects of hydrolysates on gel formation, but did not improve gel quality compared to the control. These results provide insights into the influencing mechanism of SPI hydrolysates and their glycosylated products on SPI gel formation.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Development and characterization of novel bigels based on monoglyceride-beeswax oleogel and high acyl gellan gum hydrogel for lycopene delivery

Qiaomei Zhu et al.

Summary: The study developed novel bigels as a semi-solid vehicle for lycopene delivery, finding that a higher content of oleogel within bigels could slow down the release of lycopene.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Effects of the structure and gel properties of myofibrillar protein on chicken breast quality treated with ultrasound-assisted potassium alginate

Haibo Shi et al.

Summary: The study demonstrated that the low addition of potassium alginate treatment improved the texture of 300-days-old chicken breast, reduced liquid loss, increased the solubility of myofibrillar protein, and optimized gel properties.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Linear and non-linear rheology of heat-set soy protein gels: Effects of selective proteolysis of β-conglycinin and glycinin

Wenjie Xia et al.

Summary: Selective hydrolysis of soy protein can lead to modifications in its gelling ability, resulting in hydrolysates with different rheological properties that can be tailored by varying the degree of hydrolysis.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Heat- and cold-induced gels of desalted duck egg white/gelatin mixed system: Study on rheological and gel properties

Yalei Dai et al.

Summary: This study focused on the construction of different gel systems, including heat-induced and cold-set DDG mixed gels, and analyzed their properties. The research indicated that heat-induced gels were harder but less elastic, with higher water holding capacity and denser structure, providing basic data support for the development of gel foods.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Alginate-based emulsion micro-gel particles produced by an external/ internal O/W/O emulsion-gelation method: Formation, suspension rheology, digestion, and application to gel-in-gel beads

Duanquan Lin et al.

Summary: This study investigated external/internal O/W/O emulsion-gelation methods for preparation of alginate-based emulsion micro-gel particles. The external gelation could produce emulsion micro-gels with small size (<100 mu m), while emulsion micro-gels prepared by the internal gelation had bigger size and a more narrow size distribution. The presence of emulsion micro-gel particles prepared by the external gelation improved the Young's modulus of gel beads and delayed their structural collapse during intestinal digestion.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Influence of cyclodextrins on the gelation behavior of κ-carrageenan/konjac glucomannan composite gel

Chao Yuan et al.

Summary: The study evaluated the effects of cyclodextrins (CDs) on the gelation behavior of x-carrageenan/konjac glucomannan (KC/KGM) composite gel. The results showed that CDs reduced viscosity and yield stress, while enhancing storage modulus of the gel. Methyl-beta-CD (M-beta-CD) had the most significant impact on improving gel structure flexibility.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Effect of sucrose substitution with stevia and saccharin on rheological properties of gels from sunflower pectins

Nerea Munoz-Almagro et al.

Summary: This study investigated the rheological properties of gels formed with sunflower pectins under different concentrations of Ca2+, sucrose or sweeteners, and pH levels. The results showed that MF-pectin formed the firmest gel under various conditions, while UF-pectin combined with sweeteners at pH 3.0 produced the strongest gels. The findings suggest the potential of using stevia and saccharin in the development of low-calorie and low-glycemic index gels from sunflower pectin for a wide range of food applications.

FOOD HYDROCOLLOIDS (2021)

Article Biochemistry & Molecular Biology

Preparation of pH-sensitive carboxymethyl cellulose/chitosan/alginate hydrogel beads with reticulated shell structure to deliver Bacillus subtilis natto

Mengmeng Wang et al.

Summary: A novel strategy was designed to construct a pH-sensitive hydrogel structure that is stable in simulated gastric fluid but breaks down in simulated intestinal fluid. The structure showed a high embedding rate of Bacillus subtilis natto and sustained release for over 10 hours, balancing the conflicting properties of pH sensitivity and sustained release.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Biochemistry & Molecular Biology

Recent insights into carrageenan-based bio-nanocomposite polymers in food applications: A review

Mohsin B. Aga et al.

Summary: Nanotechnology has been utilized in food packaging to develop innovative materials with enhanced properties by incorporating nanomaterials like TiO2, SiO2, and nano clays into carrageenan. Carrageenan-based bio-nanocomposite packaging materials show promising results in increasing food quality and shelf stability, while also addressing environmental concerns with their high biodegradability index.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Pharmacology & Pharmacy

A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications

Amina Ahmady et al.

Summary: Bioadhesive polymers are versatile in medical and pharmaceutical inventions, improving drug absorption and therapeutic outcomes. Gelatine, despite its biodegradability and biocompatibility, has limited applications due to poor adhesive properties. Strategies like chemical modification and blending with other biomaterials are proposed to enhance its bioadhesivity.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Article Chemistry, Applied

Maximizing the oil content in polysaccharide-based emulsion gels for the development of tissue mimicking phantoms

Cynthia Fontes-Candia et al.

Summary: Formulations based on agar and κ-carrageenan were investigated for the production of emulsion gels applicable as tissue mimicking phantoms. The polysaccharides were found suitable for designing a variety of tissue mimicking phantoms with a broad range of mechanical and dielectric properties.

CARBOHYDRATE POLYMERS (2021)

Article Chemistry, Applied

Mixed starch/chitosan hydrogels: elastic properties as modelled through simulated annealing algorithm and their ability to strongly reduce yellow sunset (INS 110) release

Lucas de Souza Soares et al.

Summary: A method to improve the elasticity of hydrogels and slow down the release of dyes was developed by partially replacing the gelling agent with chitosan.

CARBOHYDRATE POLYMERS (2021)

Article Food Science & Technology

Development and mechanical properties of soy protein isolate-chitin nanofibers complex gel: The role of high-pressure homogenization

Qi-Hui Chen et al.

Summary: By introducing nanofibers into the SPI gel system, the gelation time can be significantly shortened, the gelation concentration reduced, and the gel strength enhanced. The nanofibers provide an initial framework for gel formation and fill the gel structure through electrostatic interactions, supporting the formation of SPI-CNFs complex gel.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

Article Materials Science, Biomaterials

Phloroglucinol-enhanced whey protein isolate hydrogels with antimicrobial activity for tissue engineering

Varvara Platania et al.

Summary: Processing Whey Protein Isolate into hydrogels enriched with phloroglucinol can enhance solubilization, antimicrobial activity, without affecting mechanical properties, and support stem cell adhesion and growth.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Chemistry, Applied

Rheological and structural properties of sodium caseinate as influenced by locust bean gum and κ-carrageenan

Meng-xue Tang et al.

Summary: The study investigated the interactions between sodium caseinate and polysaccharide using locust bean gum and kappa-carrageenan. It was found that an increase in polysaccharide content led to increased modulus in the mixtures. LAOS test and Fourier transform were used to detect slight rheological differences caused by microstructure changes.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Calcium-induced-gel properties for low methoxyl pectin in the presence of different sugar alcohols

Li Wan et al.

Summary: The study found that different types and concentrations of sugar alcohols significantly affected the gelation of LMP, with erythritol-gels showing the highest value and sorbitol-gels the lowest. All LMP gels had good water holding capacity when the sugar alcohols concentration was less than 20%. Additionally, erythritol-gels exhibited better elasticity and formed faster.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Structural characterization of interpenetrating network formation of high acyl gellan and maltodextrin gels

K. M. Kanyuck et al.

Summary: The study found that the mixed-gel of high acyl gellan gum and maltodextrin formed an interpenetrating network, combining soft and flexible properties with firm and brittle properties. With maltodextrin dominating small deformation rheology and high acyl gellan gum dominating the fracture point, the material properties indicated the type of structural organization in the mixed gel network.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Combined systems of starch and Gleditsia triacanthos galactomannans: Thermal and gelling properties

Ursula Loser et al.

Summary: The galactomannans fraction extracted from Gleditsia triacanthos seeds improved the viscosity profile and accelerated the gelation process of starch-gum systems. It also helped to improve the stiffness of starch gels and reduce or maintain their brittleness after 7 days of storage. The addition of galactomannans did not significantly affect the texture properties of the gels under different pH conditions, indicating its potential as a food texture modifier in starch-based products.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Steady/dynamic rheological characterization and FTIR study on wheat starch-sage seed gum blends

Amir Pourfarzad et al.

Summary: The study revealed that higher levels of sage seed gum (SSG) incorporation in wheat starch (WS) blends resulted in changes in rheological properties and particle size, as well as promoted interactions between starch and SSG. Additionally, the structure of starch was influenced by the presence of SSG.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

An integrated manufacturing strategy to fabricate delivery system using gelatin/alginate hybrid hydrogels: 3D printing and freeze-drying

Chih-Chun Kuo et al.

Summary: The study used extrusion-based 3D printing to fabricate bioscaffolds with gelatin and alginate hybrid hydrogels, demonstrating that materials considered 3D printable under certain conditions exhibit shear-thinning flow behavior and suitable rheological properties for 3D printing. Bioscaffolds prepared with specific formulations showed significant increase in hardness after freeze-drying, which also helps extend shelf life and enhance mechanical properties.

FOOD HYDROCOLLOIDS (2021)

Article Food Science & Technology

Pulsed electric fields (PEF) treatment to enhance starch 3D printing application: Effect on structure, properties, and functionality of wheat and cassava starches

Bianca Chieregato Maniglia et al.

Summary: This study found that pulsed electric fields have different effects on cassava starch and wheat starch, potentially enhancing 3D printing applications.

INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2021)

Article Biochemistry & Molecular Biology

Development of soy protein isolate/κ-carrageenan composite hydrogels as a delivery system for hydrophilic compounds: Monascus yellow

Qian Zhang et al.

Summary: This study aimed to develop SPI and KC composite hydrogels as a delivery system for hydrophilic compounds, with the findings indicating that these composite gels have tougher, more uniform, more compact, and sustained-release properties. The results suggest that non-covalent interactions are involved in the formation of SPI/KC composite hydrogels, and the release behavior of monascus yellow in the hydrogel network can be well described by a mathematical model.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Engineering, Chemical

Ice recrystallization inhibition of commercial κ-, ι-, and λ-carrageenans

Bercem Kiran-Yildirim et al.

Summary: In this study, the structural composition of commercial kappa (kappa)-, iota (iota)-, lambda (lambda)-carrageenans was examined using H-1 NMR spectroscopy, and the IRI activity of these different carrageenan samples was investigated in sucrose solution. The results revealed that the IRI activities varied among different carrageenan suppliers, which may be attributed to structural and possibly other compositional differences.

JOURNAL OF FOOD ENGINEERING (2021)

Article Food Science & Technology

Effect of temperature and pH on the gelation, rheology, texture, and structural properties of whey protein and sugar gels based on Maillard reaction

Wang Wen-qiong et al.

Summary: This study found that under higher temperature and alkaline conditions, the formation of whey protein gel was accelerated, with increased exposure of tryptophan on the protein surface leading to higher hydrophobicity of the protein gel.

JOURNAL OF FOOD SCIENCE (2021)

Article Food Science & Technology

Effects of cryoconcentrate blueberry juice incorporation on gelatin gel: A rheological, textural and bioactive properties study

Nidia Casas-Forero et al.

Summary: Adding 20 g/100 g of cryoconcentrate blueberry juice (CBJ) can enhance the gel structure, showing the highest gelling and melting temperatures, as well as significantly increasing initial gel strength, hardness, gumminess, and chewiness. Furthermore, CBJ contains rich bioactive components, maintaining the quality of the gelatin gel.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

Article Polymer Science

3D printed agar/ calcium alginate hydrogels with high shape fidelity and tailorable mechanical properties

Jilong Wang et al.

Summary: In this study, calcium alginate/agar 3D structures were printed with high resolution and tailorable mechanical properties by a thermal-assisted 3D printing method. The introduction of agar altered the rheological properties of the ink, increasing its viscosity for higher precision. The crosslinking of calcium alginate affected the swelling behavior and mechanical properties of printing gels after printing.

POLYMER (2021)

Article Polymer Science

Rheological Properties of Fish Gelatin Modified with Sodium Alginate

Svetlana R. Derkach et al.

Summary: Polyelectrolyte complexes of sodium alginate and gelatin obtained from cold-blooded fish were studied for their potential application as structure-forming agents in food hydrogels. The mass ratio of sodium alginate to gelatin played a crucial role in the sol-gel transition and rheological behavior of the complexes. The observed rheological behavior characterized the gels formed by fish gelatin modified with sodium alginate as typical viscoelastic soft matter, with certain stress thresholds indicating the gel strength limit.

POLYMERS (2021)

Article Food Science & Technology

Phase behavior and rheological properties of basil seed gum/whey protein isolate mixed dispersions and gels

Vahideh Sarabi-Aghdam et al.

Summary: The study examined the effects of adding basil seed gum (BSG) to whey protein isolate (WPI) dispersions on phase behavior, flow properties, and viscoelastic behavior. Results showed that increasing BSG concentration significantly enhanced the rheological properties and viscoelastic behavior of the solutions. The addition of BSG also influenced the temperature sensitivity and gelation temperature of WPI.

FOOD SCIENCE & NUTRITION (2021)

Article Chemistry, Applied

Oscillatory rheology of carboxymethyl cellulose gels: Influence of concentration and pH

Carlos G. Lopez et al.

Summary: This study found that the addition of HCl promotes gel formation of carboxymethyl cellulose, while the addition of NaOH suppresses it. At neutral pH, the storage modulus of NaCMC gels at a given concentration does not vary significantly.

CARBOHYDRATE POLYMERS (2021)

Review Chemistry, Multidisciplinary

Translational Applications of Hydrogels

Santiago Correa et al.

Summary: Advances in hydrogel technology have led to diverse applications in medicine and environmental engineering, providing solutions for various diseases and medical conditions. Collaboration across disciplines is essential for the development of contemporary hydrogels to accomplish complex biological tasks in different fields.

CHEMICAL REVIEWS (2021)

Article Chemistry, Applied

Interpenetrating polymer network hydrogels of soy protein isolate and sugar beet pectin as a potential carrier for probiotics

Wenjia Yan et al.

Summary: The combination of SPI and SBP can be used to prepare an IPN hydrogel with tunable properties. The addition of probiotics resulted in changes in gel properties, decreasing storage modulus and hardness. Probiotics exposed tryptophan-containing extension regions within SPI molecules and hindered the formation of covalent cross-links or physical interactions during gelation.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

The effect of whey protein-puerarin interactions on the formation and performance of protein hydrogels

Yejun Zhong et al.

Summary: The study investigates the impact of protein-polyphenol interactions on the formation of heat-set protein hydrogels. It was found that hydrogen bonding was the main interaction between whey protein isolate (WPI) and puerarin (PUE). By altering the polyphenol concentration, the rheological properties of the hydrogels could be modulated, with increases in complex shear modulus, hardness, and resilience observed with higher PUE levels. This research offers valuable insights for fortifying functional foods with polyphenol-based nutraceuticals like puerarin.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Microstructural changes during alkali- and heat induced gelation of konjac glucomannan

Tao Zhang et al.

Summary: The study investigated the structural changes of konjac glucomannan (KGM) during heat-induced gelation, revealing that gelation requires both heat and alkali-induced deacetylation. Deacetylation was found to be the rate-determining step in the process, leading to particle aggregation and interaction to form a network structure. This understanding was aided by Dynamic Light Scattering (DLS) and Atomic Force Microscopy (AFM) results.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Effect of salt addition on iota-carrageenan solution properties

Mohamed Salem Elfaruk et al.

Summary: The addition of salt enhances the storage modulus, gel-sol transition temperature, thermal stability, and helical aggregation of polysaccharides, while decreasing water mobility and transforming the microstructure. These changes are intimately associated with dynamic interactions at the molecular level.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

The influence of amylose and amylopectin on water retention capacity and texture properties of frozen-thawed konjac glucomannan gel

Longchen Shang et al.

Summary: This study investigated the effects of different types of starches and frozen conditions on the water retention capacity and texture properties of frozen KGM-Starch blended gel. Results showed that starch types and concentrations significantly affected the syneresis rate, water holding capacity, and texture properties of the gel. Additionally, different starch types could improve the frozen-thawed stability of the KGM gel.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Shear-induced synergistic effects of konjac glucomannan and waxy potato starch on viscosity and gel strength

Fang Fang

Summary: This study investigated the effects of konjac glucomannan (KGM) on the gel formation of waxy potato starch (WPS) under low shear. The results showed that KGM accelerated the gel formation process and enhanced the elasticity and storage modulus of the gel. Strong synergistic effects of shear and KGM on the viscosity and storage modulus were observed during the gel formation process, independent of the properties of the KGM dispersion.

FOOD HYDROCOLLOIDS (2021)

Article Biochemistry & Molecular Biology

Factors influencing the adhesive behavior of carboxymethyl cellulose-based hydrogel for food applications

Shiliang Dong et al.

Summary: The adhesive performance of CMC hydrogels under different conditions was studied, and the optimal CMC type and conditions for cigar wrapper application were identified. The experimental results showed that hydrogels prepared using boiled water at neutral pH exhibited good adhesive behavior and were not significantly affected by storage temperature.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Engineering, Chemical

Investigation of functional, textural, and thermal properties of soluble complex of whey protein-xanthan gum hydrogel

Majid Pilevaran et al.

Summary: The study focused on developing a heat-induced hydrogel consisting of whey protein concentrate (WPC) and different concentrations of xanthan gum (XG) to improve the texture and thermal stability. The addition of XG resulted in higher porosity and water-holding capacity in the hydrogel, while reducing elasticity compared to WPC hydrogel. The WPC-XG composite hydrogel exhibited increased thermal stability and ability to retain water, making it a potential candidate for applications in the food industry.

JOURNAL OF FOOD PROCESS ENGINEERING (2021)

Article Food Science & Technology

Synergistic gelation in the hybrid gel of scallop (Patinopecten yessoensis) male gonad hydrolysates and xanthan gum

Jia-Nan Yan et al.

Summary: This study evaluated the gel and microstructure properties of scallop male gonads hydrolysates (SMGHs) combined with xanthan gum (XG). The addition of XG significantly improved the rheological properties of SMGHs, indicating a strong binding between SMGHs and XG. The SMGHs/XG gel showed potential to be applied in the food industry, especially in delivery systems for bioactive compounds.

JOURNAL OF FOOD SCIENCE (2021)

Article Agriculture, Multidisciplinary

Development of cress seed gum hydrogel and investigation of its potential application in the delivery of curcumin

Saeedeh Shahbazizadeh et al.

Summary: The study demonstrates that cress seed gum (CSG) can be a promising polysaccharide for preparing physically cross-linked hydrogel as a curcumin delivery system. CSG hydrogel can protect curcumin during food thermal processing and digestion time, making it a valuable ingredient in modern food formulations.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2021)

Article Chemistry, Applied

Structural, gelation properties and microstructure of rice glutelin/sugar beet pectin composite gels: Effects of ionic strengths

Ya-Ru Wang et al.

Summary: The study found that adding 200 mM calcium ions to the RG/SBP composite gels can enhance their performance, including rheological properties, textural properties, and water holding capacity. The addition of SBP and calcium ions strengthens the hydrophobic interaction between RG molecules and improves gel formation.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

Strong and elastic pea protein hydrogels formed through pH-shifting method

Peineng Zhu et al.

Summary: The research revealed a modified pH-shifting method for the preparation of pea protein gels with superior strength, forming a strong and elastic gel network structure under high temperature conditions, demonstrating excellent mechanical strength and water holding capacity.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Properties of the konjac glucomannan and zein composite gel with or without freeze-thaw treatment

Rui Lai et al.

Summary: The study found that adding zein or conducting freeze-thaw treatment can improve the storage modulus of KGM composite gels, but excessive zein content may cause partial phase separation. By determining the target characteristics ratio of the final product, composite gels can be better prepared.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Stress relaxation of particulate whey protein hydrogels

Baoping Yang et al.

Summary: The relaxation mechanics of hydrogels depend on how stresses are dissipated: through the polymeric network, through the flow of the entrapped solvent, or through both mechanisms. Particulate protein gels present two well identified and separated relaxation regimes: poroelastic and viscoelastic.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Effects of pH and temperature on the structure, rheological and gel-forming properties of sugar beet pectins

Tao Zhang et al.

Summary: In this study, sugar beet pectin was modified by alkaline treatment at both 25 degrees C and 3 degrees C to produce gel-type pectins with stable elastic gel properties. The low temperature effectively inhibited the beta-elimination of SBP and resulted in higher molecular weight and galacturonic acid content. SBP treated under pH 11 and 12 at 3 degrees C exhibited low degree of methylation and acetylation, forming stable elastic gels that were confirmed to be frequency-independent through rheological analysis.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Heat-induced gel formation by whey protein isolate- Lycium barbarum polysaccharides at varying pHs

Zhendong He et al.

Summary: The study showed that composite gels with 0.1% Lycium barbarum polysaccharides exhibited the greatest functional value, while gels with 1% LBP had higher porosity. Whey protein formed different types of gels at varying pH levels, but showed no significant difference in hydration properties.

FOOD HYDROCOLLOIDS (2021)

Article Chemistry, Applied

Preparation and structural characteristics of composite alginate/casein emulsion gels: A microscopy and rheology study

Peiyuan Li et al.

Summary: The study found that oil droplets were always located in the casein-dominant regions regardless of the polymer types used for preparing emulsions. As Alg concentration increased, the gelation time of composite emulsion gels shortened, and the incorporation of oil droplets also affected the phase separation rate and extent between Alg and caseins.

FOOD HYDROCOLLOIDS (2021)

Article Biochemistry & Molecular Biology

Development of emulsion gelatin gels for food application: Physicochemical, rheological, structural and thermal characterization

Wafa Taktak et al.

Summary: This study aimed to prepare emulsion gels based on European eel skin gelatin (ESG), which exhibited interesting antioxidant and functional properties. The ESG was able to stabilize European eel oil (EO) emulsions effectively, showing a rigid and cohesive gel network with effective entrapment of EO.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Biochemistry & Molecular Biology

Preparation and characterization of konjac glucomannan and gum arabic composite gel

Zhenyu Li et al.

Summary: This study evaluated composite gels prepared with konjac glucomannan (KGM) and gum arabic (GA) using various analytical methods, revealing gel stratification at certain concentrations, changes in microstructure with GA concentration, and increases in water solubility and water absorption with higher GA concentrations. Rheological analysis showed the gels to be non-Newtonian pseudoplastic fluids with different deformation characteristics.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Biochemistry & Molecular Biology

Fucoidan hydrogels induced by k-carrageenan: Rheological, thermal and structural characterization

Nan Wang et al.

Summary: The study confirmed the formation of hydrogen bonds between FUC and KC, with the addition of KC significantly improving water retention and frost resistance of FUC. The FUC-KC mixtures displayed higher gelling nature and thermal stability.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Materials Science, Multidisciplinary

Gelatin-alginate-hyaluronic acid inks for 3D printing: effects of bioglass addition on printability, rheology and scaffold tensile modulus

Marcos Bertuola et al.

Summary: This study investigated the printability and rheological properties of gelatin-alginate-hyaluronic acid inks mixed with bioactive glass for 3D bioprinting. The addition of bioactive glass impacted the storage modulus and viscosity of the inks, but improved the printing fidelity and tensile modulus of the scaffolds. Furthermore, the scaffolds showed the formation of hydroxyapatite layer and supported the attachment and growth of fibroblasts, suggesting their potential for soft tissue regeneration research.

JOURNAL OF MATERIALS SCIENCE (2021)

Article Food Science & Technology

Rheological and thermal characterization of pinto saltillo bean (Phaseolus vulgaris L.) protein isolates/sodium alginate gels

Joel Enrique Pena-Chaidez et al.

Summary: The study found that the PSBIP-SA system exhibits cosolubility at low concentrations, behaving as a shear-thinning fluid; frequency studies showed that SA concentrations higher than 20 g/L can enhance the mechanical spectra, improving the properties of binary gels; viscoelastic analyses indicated that SA reduces the random associations of proteins in mixed gels.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

Article Food Science & Technology

Pectin-sodium caseinat hydrogel containing olive leaf extract-nano lipid carrier: Preparation, characterization and rheological properties

Farnaz Ahmadzadeh Nobari Azar et al.

Summary: The study successfully encapsulated olive leaf extract in nanostructured lipid carrier and loaded it into a pectin-sodium caseinate hydrogel network, maintaining its antioxidant properties. The OLE-NLC containing hydrogel showed good retention of antioxidant activity.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

Article Food Science & Technology

Calcium-induced-gel properties for ι-carrageenan in the presence of different charged amino acids

Chengrong Wen et al.

Summary: Different charged amino acids, such as arginine and glutamic acid, have varying effects on the gel properties of calcium-iota-carrageenan, with arginine and glutamic acid weakening the water mobility of the gel, while glutamine has no significant influence. Additionally, glutamine stabilizes the gel structure through hydrogen bonding and weak electrostatic interaction, while arginine and glutamic acid affect gel formation through hydrogen bonding and strong electrostatic interaction.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

Article Food Science & Technology

Rheological properties of xanthan-modified fish gelatin and its potential to replace mammalian gelatin in low-fat stirred yogurt

Mengdi Yin et al.

Summary: Fish gelatin modified with xanthan gum is a promising alternative to mammalian gelatin in low-fat yogurt production, showing improved rheological properties. The addition of xanthan gum has a significant impact on the storage modulus in the gel system.

LWT-FOOD SCIENCE AND TECHNOLOGY (2021)

Review Food Science & Technology

Recent advances in carrageenan-based delivery systems for bioactive ingredients: A review

Yue Dong et al.

Summary: Carrageenan-based delivery systems for bioactive ingredients show great potential in the food industry, with various types such as nanoparticles, hydrogels, emulsions, and complexes. Factors affecting the performance of these systems include carrageenan type, crosslinking agents, and material adding order. Future research trends involve combining different delivery systems and developing new environmentally responsive systems.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Article Polymer Science

Fabrication of Flexible pH-Responsive Agarose/Succinoglycan Hydrogels for Controlled Drug Release

Yiluo Hu et al.

Summary: Agarose/succinoglycan hydrogels exhibit significantly improved flexibility, stability, and swelling pattern compared to agarose gels alone, and they also demonstrate pH-responsive drug delivery of ciprofloxacin. The non-toxicity of these hydrogels makes them potential natural biomaterials for biomedical applications.

POLYMERS (2021)

Article Food Science & Technology

Effect of agar and gellan gum on structured guava (Psidium guajava L.): Rheological behavior and gastrointestinal digestion in vitro

Juliana Nascimento da Costa et al.

Summary: The study found that structured guava produced by adding agar and low acyl gellan formed a complete gel network at around 20 degrees Celsius, maintaining stability of ascorbic acid, total antioxidant activity, and total extractable polyphenols. While the use of agar and GG did not interfere with the antioxidant properties of the product, they did influence the texture and appearance of SG.

FOOD BIOSCIENCE (2021)

Article Materials Science, Multidisciplinary

Biologically Enhanced Starch Bio-Ink for Promoting 3D Cell Growth

Pei Zhuang et al.

Summary: A novel 3D printable nanocomposite starch hydrogel was developed with enhanced biocompatibility for promoting 3D cell growth, utilizing gelatin nanoparticles and collagen. The unique rheological properties of the hydrogel, along with the homogeneous microporous structure containing collagen fibers and gelatin nanoparticles, support cell attachment and proliferation. The cell metabolic activity study confirmed the remarkable enhancement of biological function of the developed starch hydrogel, making it a highly desirable bio-ink for advancing 3D tissue engineering.

ADVANCED MATERIALS TECHNOLOGIES (2021)

Article Food Science & Technology

The rheological characteristics of soy protein isolate-glucose conjugate gel during simulated gastrointestinal digestion

Feng Liu et al.

Summary: In this study, SPI-glc conjugate gels were prepared using wet Maillard reaction, with the highest degree of grafting achieved at 4 hours. These conjugate gels exhibited slower digestion kinetics after gastric digestion.

FOOD STRUCTURE-NETHERLANDS (2021)

Article Chemistry, Applied

Rheological and pH dependent properties of injectable and controlled release hydrogels based on mushroom hyperbranched polysaccharide and xanthan gum

Ruquan Zhang et al.

Summary: Hydrogels with thixotropic and pH-sensitive properties, fabricated from xanthan gum and hyperbranched-Dglucan crosslinked with sodium trimetaphosphate, exhibit injectability and controlled release behavior. The introduction of TM3a results in higher yield stress and elastic modulus, along with pH-dependent swelling and controlled release properties, making them suitable for tissue engineering and drug release applications.

CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS (2021)

Review Public, Environmental & Occupational Health

The antiviral activity of iota-, kappa-, and lambda-carrageenan against COVID-19: A critical review

Andri Frediansyah

Summary: Carrageenan has demonstrated strong antiviral activity against various coronaviruses and non-coronaviruses, although clinical trials are needed to evaluate its specific efficacy for COVID-19 treatment despite some positive results in conjunction with other oral medications.

CLINICAL EPIDEMIOLOGY AND GLOBAL HEALTH (2021)

Article Food Science & Technology

Starch-Based Hydrogels Produced by High-Pressure Processing (HPP): Effect of the Starch Source and Processing Time

Dominique Larrea-Wachtendorff et al.

Summary: Starch-based hydrogels are natural polymeric structures with high scientific interest, and the starch source and processing time have significant effects on gel formation and physical characteristics. Tapioca and rice starch HPP hydrogels showed better performance, while rice, wheat, and corn starch HPP hydrogels exhibited a cream-like structure.

FOOD ENGINEERING REVIEWS (2021)

Article Biochemistry & Molecular Biology

Controlling the rheological properties of wheat starch gels using Lepidium perfoliatum seed gum in steady and dynamic shear

A. R. Yousefi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Nanoscience & Nanotechnology

Hydrogel microparticles for biomedical applications

Andrew C. Daly et al.

NATURE REVIEWS MATERIALS (2020)

Article Food Science & Technology

Development of Corn Fiber Gum-Soybean Protein Isolate Double Network Hydrogels Through Synergistic Gelation

Wenjia Yan et al.

FOOD AND BIOPROCESS TECHNOLOGY (2020)

Article Biochemistry & Molecular Biology

Rheological and ion-conductive properties of injectable and self-healing hydrogels based on xanthan gum and silk fibroin

Ruquan Zhang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Multidisciplinary

Understanding the rheology of novel guar-gellan gum composite hydrogels

Anjula Katoch et al.

MATERIALS LETTERS (2020)

Article Biochemistry & Molecular Biology

pH-responsive hybrid hydrogels: Chondroitin sulfate/casein trapped silica nanospheres for controlled drug release

Andressa Renatta Simao et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Synthesis and rheological characterization of a novel shear thinning levan gellan hydrogel

Revathy Nair et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Chemistry, Applied

Casein-based hydrogels: A mini-review

Luis Gustavo Lima Nascimento et al.

FOOD CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Studies on the physicochemical properties, gelling behavior and drug release performance of agar/κ-carrageenan mixed hydrogels

Jingkun Zhao et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Biomaterials

Fumaric acid incorporated Ag/agar-agar hybrid hydrogel: A multifunctional avenue to tackle wound healing

Syed Ilias Basha et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Article Chemistry, Applied

Use of a crosslinked casein micelle hydrogel as a carrier for jaboticaba (Myrciaria cauliflora) extract

Luis Gustavo Lima Nascimento et al.

FOOD HYDROCOLLOIDS (2020)

Review Food Science & Technology

Pharmaceutical and Biomedical Applications of Native and Modified Starch: A Review

Maria Aparecida Vieira Teixeira Garcia et al.

STARCH-STARKE (2020)

Article Polymer Science

Light Processable Starch Hydrogels

Camilla Noe et al.

POLYMERS (2020)

Article Biochemistry & Molecular Biology

Drug polarity effect over the controlled release in casein and chondroitin sulfate-based hydrogels

Andressa Renatta Simao et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Review Multidisciplinary Sciences

Effects of extracellular matrix viscoelasticity on cellular behaviour

Ovijit Chaudhuri et al.

NATURE (2020)

Article Pharmacology & Pharmacy

3D printing of extended-release tablets of theophylline using hydroxypropyl methylcellulose (HPMC) hydrogels

Yiliang Cheng et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Article Food Science & Technology

Concentration-dependent improvement of gelling ability of soy proteins by preheating or ultrasound treatment

Jiamei Wang et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2020)

Article Food Science & Technology

Dry heating treatment: A potential tool to improve the wheat starch properties for 3D food printing application

Bianca C. Maniglia et al.

FOOD RESEARCH INTERNATIONAL (2020)

Review Food Science & Technology

Design principles of food gels

Yiping Cao et al.

NATURE FOOD (2020)

Review Polymer Science

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

Christopher D. Spicer

POLYMER CHEMISTRY (2020)

Article Mechanics

Fatigue of hydrogels

Ruobing Bai et al.

EUROPEAN JOURNAL OF MECHANICS A-SOLIDS (2019)

Review Biochemistry & Molecular Biology

Health-promoting effects of konjac glucomannan and its practical applications: A critical review

Ramya Devi Devaraj et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Food Science & Technology

Starch-based nanocarriers as cutting-edge natural cargos for nutraceutical delivery

Hadis Rostamabadi et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2019)

Article Chemistry, Applied

Gelatin as texture modifier and porogen in egg white hydrogel

Jamal Babaei et al.

FOOD CHEMISTRY (2019)

Review Polymer Science

Advanced material applications of starch and its derivatives

Emmanuel Ogunsona et al.

EUROPEAN POLYMER JOURNAL (2018)

Article Food Science & Technology

Rheology and microstructure of kefiran and whey protein mixed gels

Hosayn Kazazi et al.

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2017)

Article Food Science & Technology

Influence of sage seed gum on some physicochemical and rheological properties of wheat starch

Ali Reza Yousefi et al.

STARCH-STARKE (2017)

Review Chemistry, Multidisciplinary

Rheological properties of peptide-based hydrogels for biomedical and other applications

Congqi Yan et al.

CHEMICAL SOCIETY REVIEWS (2010)