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JOURNAL OF CLINICAL INVESTIGATION (2011)
Tribbles 3: A Novel Regulator of TLR2-Mediated Signaling in Response to Helicobacter pylori Lipopolysaccharide
Sinead M. Smith et al.
JOURNAL OF IMMUNOLOGY (2011)
TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma
Jing Zhang et al.
ORAL ONCOLOGY (2011)
PI3K and ERK-Induced Rac1 Activation Mediates Hypoxia-Induced HIF-1α Expression in MCF-7 Breast Cancer Cells
Jun Du et al.
PLOS ONE (2011)
TRIB3 protein denotes a good prognosis in breast cancer patients and is associated with hypoxia sensitivity
Marloes Wennemers et al.
RADIOTHERAPY AND ONCOLOGY (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response
Marloes Wennemers et al.
BREAST CANCER RESEARCH (2011)
Rethinking ovarian cancer: recommendations for improving outcomes
Sebastian Vaughan et al.
NATURE REVIEWS CANCER (2011)
Autophagic degradation of active caspase-8 A crosstalk mechanism between autophagy and apoptosis
Wen Hou et al.
AUTOPHAGY (2010)
An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-κB activation and cytokine levels
Shane P. Duggan et al.
CARCINOGENESIS (2010)
MMP-2 alters VEGF expression via αVβ3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells
Chandramu Chetty et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
Kasper M. A. Rouschop et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
Yung-Jue Bang et al.
LANCET (2010)
Gene-expression-based prognostic assays for breast cancer
Chungyeul Kim et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
Abnormal expression of TRIB3 in colorectal cancer: a novel marker for prognosis
N. Miyoshi et al.
BRITISH JOURNAL OF CANCER (2009)
Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5′-UTR
Tiit Oerd et al.
GENE (2009)
Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model
Nicoletta Gagliano et al.
ONCOLOGY REPORTS (2009)
Signal integration by JNK and p38 MAPK pathways in cancer development
Erwin F. Wagner et al.
NATURE REVIEWS CANCER (2009)
The biology of ovarian cancer: new opportunities for translation
Robert C. Bast et al.
NATURE REVIEWS CANCER (2009)
Survival of cancer cells is maintained by EGFR independent of its kinase activity
Zhang Weihua et al.
CANCER CELL (2008)
E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3
Ying Zhou et al.
CELLULAR SIGNALLING (2008)
TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activity
Yu Takahashi et al.
JOURNAL OF LIPID RESEARCH (2008)
The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11
C. Chen et al.
ONCOGENE (2008)
Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-κB and ATF4
T. Rzymski et al.
ONCOGENE (2008)
Radical cystectomy and extended pelvic lymphadenectomy: Survival of patients with lymph node metastasis above the bifurcation of the common iliac vessels treated with surgery only
Kenneth Steven et al.
JOURNAL OF UROLOGY (2007)
TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4
Daima Oerd et al.
EXPERIMENTAL CELL RESEARCH (2007)
TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway
Celine Jousse et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cause and place of death in patients dying with colorectal cancer
O. M. Jones et al.
COLORECTAL DISEASE (2007)
TRB3 interacts with CtIP and is overexpressed in certain cancers
Jianmin Xu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2007)
Chemotherapy: induction of stress responses
E. Tiligada
ENDOCRINE-RELATED CANCER (2006)
PPARγ agonists prevent TGFβ1 Smad3-signaling in human hepatic stellate cells
Caiyan Zhao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Hypoxia confers protection against apoptosis via PI3K/Akt and ERK pathways in lung cancer cells
Sang-Min Lee et al.
CANCER LETTERS (2006)
TRB3 is a PI 3-kinase dependent indicator for nutrient starvation
R Schwarzer et al.
CELLULAR SIGNALLING (2006)
Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis
G Chakraborty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
A Carracedo et al.
CANCER CELL (2006)
Emerging roles of pseudokinases
Jerome Boudeau et al.
TRENDS IN CELL BIOLOGY (2006)
A randomized phase III study of doxorubicin versus cisplatin/interferon α-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma
W Yeo et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2005)
AKT activation predicts outcome in breast cancer patients treated with tamoxifen
T Kirkegaard et al.
JOURNAL OF PATHOLOGY (2005)
Genotoxic and endoplasmic reticulum stresses differentially regulate TRB3 expression
CA Corcoran et al.
CANCER BIOLOGY & THERAPY (2005)
Photodynamic therapy as salvage treatment for local failures after definitive chemoradiotherapy for esophageal cancer
T Yano et al.
GASTROINTESTINAL ENDOSCOPY (2005)
Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions
D Örd et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
N Ohoka et al.
EMBO JOURNAL (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Lack of evidence for a role of TRB3/NIPK as an inhibitor of PKB-mediated insulin signalling in primary hepatocytes
PB Iynedjian
BIOCHEMICAL JOURNAL (2005)
Genetic Polymorphisms in peroxisome proliferator-activated receptor δ associated with obesity
HD Shin et al.
DIABETES (2004)
Increased constitutive activity of PKB/Akt in tamoxifen resistant breast cancer MCF-7 cells
NJ Jordan et al.
BREAST CANCER RESEARCH AND TREATMENT (2004)
Targeting the mitogen-activated protein kinase cascade to treat cancer
JS Sebolt-Leopold et al.
NATURE REVIEWS CANCER (2004)
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades
E Kiss-Toth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The transcription factor Six2 activates expression of the Gdnf gene as well as its own promoter
S Brodbeck et al.
MECHANISMS OF DEVELOPMENT (2004)
Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells
YH Joung et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2003)
SINK is a p65-interacting negative regulator of NF-κB-dependent transcription
M Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
TRB3:: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
KY Du et al.
SCIENCE (2003)
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
G Dontu et al.
GENES & DEVELOPMENT (2003)
SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia
AJ Bowers et al.
ONCOGENE (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
N Mitsiades et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer:: a randomised trial
AM Lacy et al.
LANCET (2002)
Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation
S Pizzimenti et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Nuclear localization of EGF receptor and its potential new role as a transcription factor
SY Lin et al.
NATURE CELL BIOLOGY (2001)
Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: A comparison between hypoxia and inhibitors of cell metabolism
A Hoffmann et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2001)
Mammalian MAP kinase signalling cascades
LF Chang et al.
NATURE (2001)
Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome
J Bao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)