Human Fecal Mucin Glycosylation as a New Biomarker in Inflammatory Bowel Diseases

Lay Summary For the first time, fecal mucins of Crohn's disease patients were analyzed by mass spectrometry. Compared with control subjects, Crohn's disease patients showed a significant decrease in sialylated glycans that we propose as new noninvasive tool for screening of intestinal diseases.

Automated summary

This study used mass spectrometry to analyze the fecal mucins of Crohn's disease patients and found a significant decrease in sialylated glycans compared to the control group. This may propose a new noninvasive tool for screening intestinal diseases.