Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 81, Issue 11, Pages 4847-4855Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.6b00469
Keywords
-
Categories
Funding
- HKUST [R9309]
- Research Grant Council of Hong Kong [ECS 605912, GRF 605113, GRF 16305314]
- National Natural Science Foundation of China [NSFC 21472160]
Ask authors/readers for more resources
The increasing interest in Achmatowicz rearrangement in organic synthesis calls for a more environmentally friendly protocol since the most popular oxidants m-CPBA and NBS produced stoichiometric organic side product (mchlorobenzoic acid or succinimide). Mechanism-guided analysis enables us to develop a new catalytic method (Oxone/KBr) for AchR in excellent yield with K2SO4 as the only side product, which greatly facilitates the purification. This protocol was integrated with other transformations, leading to a. rapid access to the highly functionalized dihydropyranones.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available