4.7 Article

Ru(II)-Catalyzed Direct C(sp2)-H Activation/Selenylation of Arenes with Selenyl Chlorides

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 81, Issue 13, Pages 5263-5269

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.6b00634

Keywords

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Funding

  1. Chinese NSF [81430080, 81125021]
  2. Major State Basic Research Development Program [2015CB910603]
  3. SIMM [CASIMM0120154002/2002]

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A new ruthenium catalytic system was developed for the construction of a C(sp(2))-Se bond with the assistance of directing groups. This protocol features mild reaction conditions, wider substrate scope, and convenient late -stage selenylation of bioactive molecules.

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