4.7 Article

One-Pot Synthesis of Arylketones from Aromatic Acids via Palladium-Catalyzed Suzuki Coupling

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 81, Issue 7, Pages 2987-2992

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b02667

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Funding

  1. National Natural Science Foundation of China [21272080]
  2. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
  3. Guangdong Province Higher Vocational Colleges and Schools Pearl River Scholar Funded Scheme

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A palladium-catalyzed one-pot procedure for the synthesis of aryl ketones has, been developed. Triazine esters when coupled with aryl boronic acids provided aryl ketones in moderate to excellent yields (up to 95%) in the presence of 1 mol % Pd(PPh3)(2)Cl-2 for 30 min.

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