Reply: Living donor liver transplantation for people with PSC

Article Surgery

Long-term outcome after living donor liver transplantation compared to donation after brain death in autoimmune liver diseases: Experience from the European Liver Transplant Registry

Melina Heinemann et al.

Summary: The study analyzed survival outcomes of living donor liver transplantation (LDLT) for autoimmune liver diseases, particularly focusing on primary sclerosing cholangitis (PSC) patients. It found that adult PSC patients had lower survival rates and increased mortality risk, with male donors and biliary complications identified as important risk factors for death after LDLT in PSC patients.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

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Article Surgery

Survival Benefit of Living-Donor Liver Transplant

Whitney E. Jackson et al.

Summary: This study examines the survival benefit of living-donor liver transplant (LDLT) and its association with the Model for End-stage Liver Disease incorporating sodium levels (MELD-Na) score. The findings suggest that LDLT provides a substantial survival benefit to patients with end-stage liver disease, even at lower MELD-Na scores as low as 11. The study challenges current perceptions regarding the timing of LDLT survival benefit.

JAMA SURGERY (2022)

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Article Gastroenterology & Hepatology