4.6 Review

Non-coding RNA and their potential role in cardiovascular diseases

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Systemic single administration of anti-inflammatory microRNA 146a-5p loaded in polymeric nanomedicines with active targetability attenuates neointimal hyperplasia by controlling inflammation in injured arteries in a rat model

Masaya Sano et al.

Summary: This study used nanomedicine to deliver miR146a-5p in a rat carotid artery balloon injury model and found that it can inhibit inflammatory response and vascular smooth muscle cell migration, as well as reduce reactive oxygen species production and proinflammatory cytokine gene expression. In a rat model, miR146a-5p attenuated NIH and vessel remodeling by reducing proinflammatory cytokine gene expression in injured arteries and monocyte/macrophage infiltration into the vascular wall.

FASEB JOURNAL (2022)

Article Biotechnology & Applied Microbiology

Relationship between Expression of Plasma lncRNA-HEIH and Prognosis in Patients with Coronary Artery Disease

Zhenying Zhang et al.

Summary: The expression of lncRNA-HEIH is significantly upregulated in the plasma of patients with coronary artery disease (CAD) compared to control subjects, and is related to the severity of CAD. CAD patients with high expression of lncRNA-HEIH have a higher incidence of dyslipidemia and CAD family history, as well as an overall higher rate of major cardiac adverse events.

DISEASE MARKERS (2021)

Review Biotechnology & Applied Microbiology

Circular RNA: Biosynthesis in vitro

Xinjie Chen et al.

Summary: circRNA, a unique noncoding RNA molecule abundant in cells, has diverse functions such as miRNA sponge and protein scaffold. It plays a significant role in medical applications like circRNA vaccines. Researchers are working on overcoming challenges in circRNA synthesis for future applications.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Article Pharmacology & Pharmacy

siRNA: Mechanism of action, challenges, and therapeutic approaches

Walhan Alshaer et al.

Summary: siRNA functions in gene silencing and targets disease-related genes, yet it faces issues such as low cellular uptake and susceptibility to degradation, requiring a carrier for protection and delivery.

EUROPEAN JOURNAL OF PHARMACOLOGY (2021)

Article Biochemistry & Molecular Biology

Long Non-Coding RNAs in Cardiovascular Diseases: Potential Function as Biomarkers and Therapeutic Targets of Exercise Training

Camila Caldas Martins Correia et al.

Summary: This review discusses the role of long non-coding RNAs (lncRNAs) in the cardiovascular system, emphasizing their importance in cardiovascular pathology and their potential as biomarkers and therapeutic targets. Additionally, the protective role of regular physical exercise against cardiovascular diseases is highlighted, although the underlying molecular mechanisms are still not well understood.

NON-CODING RNA (2021)

Review Cardiac & Cardiovascular Systems

Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019 Update From the GBD 2019 Study

Gregory A. Roth et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

LncRNA-MIAT Increased in Patients with Coronary Atherosclerotic Heart Disease

Jin Tan et al.

CARDIOLOGY RESEARCH AND PRACTICE (2019)

Review Biochemistry & Molecular Biology

Mechanisms and Functions of Long Non-Coding RNAs at Multiple Regulatory Levels

Xiaopei Zhang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

Interplay of N- acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs

Tahir Ali et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)

Article Cell Biology

The long noncoding RNA XIST regulates cardiac hypertrophy by targeting miR-101

Lili Xiao et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Cardiac & Cardiovascular Systems

Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives

Wolfgang Poller et al.

EUROPEAN HEART JOURNAL (2018)

Review Chemistry, Multidisciplinary

miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

Shan-shan Zhou et al.

ACTA PHARMACOLOGICA SINICA (2018)

Review Biochemistry & Molecular Biology

Non-Coding RNA in the Pathogenesis, Progression and Treatment of Hypertension

Christiana Leimena et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

YY1-induced upregulation of lncRNA KCNQ1OT1 regulates angiotensin II-induced atrial fibrillation by modulating miR-384b/CACNA1C axis

Caijie Shen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Medicine, Research & Experimental

A circular transcript of ncx1 gene mediates ischemic myocardial injury by targeting miR-133a-3p

Mengyang Li et al.

THERANOSTICS (2018)

Article Peripheral Vascular Disease

Circulating miR-92a expression level in patients with essential hypertension: a potential marker of atherosclerosis

Y. Huang et al.

JOURNAL OF HUMAN HYPERTENSION (2017)

Article Multidisciplinary Sciences

Spatial detection of fetal marker genes expressed at low level in adult human heart tissue

Michaela Asp et al.

SCIENTIFIC REPORTS (2017)

Article Medicine, Research & Experimental

Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction

Chang Liu et al.

THERANOSTICS (2017)

Article Medicine, Research & Experimental

Plasma Long Non-Coding RNA (lncRNA) GAS5 is a New Biomarker for Coronary Artery Disease

Qiong Yin et al.

MEDICAL SCIENCE MONITOR (2017)

Article Medicine, Research & Experimental

miRNA-21 Expression in the Serum of Elderly Patients with Acute Myocardial Infarction

Zhong-Hua Wang et al.

MEDICAL SCIENCE MONITOR (2017)

Article Endocrinology & Metabolism

Hsa-circRNA11783-2 in peripheral blood is correlated with coronary artery disease and type 2 diabetes mellitus

Xuejie Li et al.

DIABETES & VASCULAR DISEASE RESEARCH (2017)

Article Medicine, General & Internal

Expression of miR-126 and its potential function in coronary artery disease.

Xiaoyan Wang et al.

AFRICAN HEALTH SCIENCES (2017)

Article Pharmacology & Pharmacy

Profiling and bioinformatics analyses reveal differential circular RNA expression in hypertensive patients

Na Wu et al.

CLINICAL AND EXPERIMENTAL HYPERTENSION (2017)

Article Biochemistry & Molecular Biology

A novel identified circular RNA, circRNA_010567, promotes myocardial fibrosis via suppressing miR-141 by targeting TGF-β1

Bing Zhou et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

Article Medical Laboratory Technology

Comparison of Two Available RNA Extraction Protocols for microRNA Amplification in Serum Samples

Massimiliano Bergallo et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2016)

Article Cardiac & Cardiovascular Systems

miR-21 promotes fibrosis in an acute cardiac allograft transplantation model

Shashi Kumar Gupta et al.

CARDIOVASCULAR RESEARCH (2016)

Article Biotechnology & Applied Microbiology

Plasma miR-10a: A Potential Biomarker for Coronary Artery Disease

Liyun Luo et al.

DISEASE MARKERS (2016)

Editorial Material Cardiac & Cardiovascular Systems

Down-regulation of lncRNA MALAT1 reduces cardiomyocyte apoptosis and improves left ventricular function in diabetic rats

Mengyao Zhang et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)

Article Cell Biology

Long noncoding RNA Chast promotes cardiac remodeling

Janika Viereck et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

Xiaoping Chen et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

Tools for Sequence-Based miRNA Target Prediction: What to Choose?

Angela L. Riffo-Campos et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Biochemical Research Methods

C-It-Loci: a knowledge database for tissue-enriched loci

Tyler Weirick et al.

BIOINFORMATICS (2015)

Review Oncology

Circular RNA: A new star of noncoding RNAs

Shibin Qu et al.

CANCER LETTERS (2015)

Review Biotechnology & Applied Microbiology

MicroRNA-143/-145 in Cardiovascular Diseases

Wang Zhao et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Article Biochemistry & Molecular Biology

An update on LNCipedia: a database for annotated human lncRNA sequences

Pieter-Jan Volders et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Hematology

Role of Flow-Sensitive microRNAs in Endothelial Dysfunction and Atherosclerosis Mechanosensitive Athero-miRs

Sandeep Kumar et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)

Article Biochemical Research Methods

IncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs

Charny Park et al.

BIOINFORMATICS (2014)

Article Cardiac & Cardiovascular Systems

The Analysis of microRNA Expression Profiling for Coronary Artery Disease

Kefei Li et al.

CARDIOLOGY (2014)

Article Cardiac & Cardiovascular Systems

The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489

Kun Wang et al.

CIRCULATION RESEARCH (2014)

Article Biochemistry & Molecular Biology

circBase: a database for circular RNAs

Petar Glazar et al.

Review Pharmacology & Pharmacy

Therapeutic implications of small interfering RNA in cardiovascular diseases

Suchi Raghunathan et al.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2013)

Article Cardiac & Cardiovascular Systems

Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients

Ana V. Villar et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)

Review Biochemistry & Molecular Biology

On the classification of long non-coding RNAs

Lina Ma et al.

RNA BIOLOGY (2013)

Article Cardiac & Cardiovascular Systems

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

Thomas G. Hullinger et al.

CIRCULATION RESEARCH (2012)

Article Biochemistry & Molecular Biology

A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis

Haihai Liang et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)

Article Cardiac & Cardiovascular Systems

MicroRNAs miR-1, miR-133a, miR-133b and miR-208 Are Dysregulated in Human Myocardial Infarction

Emanuela Bostjancic et al.

CARDIOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Circulating MicroRNAs in Patients With Coronary Artery Disease

Stephan Fichtlscherer et al.

CIRCULATION RESEARCH (2010)

Article Cardiac & Cardiovascular Systems

Role of Ca2+/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy

Clint L. Miller et al.

CIRCULATION RESEARCH (2009)

Article Biochemistry & Molecular Biology

miRecords: an integrated resource for microRNA-target interactions

Feifei Xiao et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy

Zhiqiang Lin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Cardiac & Cardiovascular Systems

siRNA silencing reveals role of vascular cell adhesion molecule-1 in vascular smooth muscle cell migration

Erik J. Petersen et al.

ATHEROSCLEROSIS (2008)

Review Chemistry, Multidisciplinary

Exploring in vitro roles of siRNA in cardiovascular disease

Yu Tang et al.

ACTA PHARMACOLOGICA SINICA (2007)

Review Biochemistry & Molecular Biology

Non-coding RNA

JS Mattick et al.

HUMAN MOLECULAR GENETICS (2006)

Article Biochemistry & Molecular Biology

miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes

Paul W. C. Hsu et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

miRBase: microRNA sequences, targets and gene nomenclature

Sam Griffiths-Jones et al.

NUCLEIC ACIDS RESEARCH (2006)