Non-coding RNA and their potential role in cardiovascular diseases

Background: Cardiovascular diseases are the leading cause of mortality worldwide. The timely diagnosis of CVD is still an unmet challenge. Non-coding RNAs which were earlier considered to be junk DNA are now considered to play crucial role as potential transcriptional regulators and therapeutic targets for treatment of CVDs.Methodology: A literature search has been performed on PubMed, SCOPUS where keywords such as non- coding RNAs and coronary artery disease and miRNAs and Myocardial infarction or cardiovascular diseases were used with no date restriction in writing this review article.Conclusion: This review focus on the role of non- coding RNAs in cardiovascular disease along with the database which can enhance the efficiency of experimental analysis of non-coding RNAs.

Automated summary

This review article discusses the role of non-coding RNAs in cardiovascular diseases and the databases that can improve the efficiency of experimental analysis of non-coding RNAs. Cardiovascular diseases are the leading cause of mortality worldwide, and timely diagnosis remains a challenge. Non-coding RNAs have been proven to play a crucial role in transcriptional regulation and treatment of cardiovascular diseases.