Alert for molecular data interpretation when using Enterococcus faecium reference strains reclassified as Enterococcus lactis

Article Infectious Diseases

The interplay between community and hospital Enterococcus faecium clones within health-care settings: a genomic analysis

Sebastiaan J. van Hal et al.

Summary: The study collected 1095 hospital E faecium sequences from 34 countries, augmented by 33 published sequences. It showed that A1 likely emerged as a clone from A2, and that A2 represents a genetic continuum between A1 and community E faecium. The study also found that A2 and B isolates entering the hospital are important reservoirs for ongoing A1 adaptation.

LANCET MICROBE (2022)

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Article Immunology

Development and Characterization of High-Throughput Caenorhabditis elegans - Enterococcus faecium Infection Model

Alexey V. Revtovich et al.

Summary: The genus Enterococcus, including E. faecalis and E. faecium, are clinically relevant Gram-positive pathogens with increasing antimicrobial resistance issues. Researchers developed a high-throughput C. elegans-E. faecium infection model that mimics key aspects of murine peritonitis models, aiding in the identification of new treatments for E. faecium infections.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

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Article Environmental Sciences

Diversity of metal and antibiotic resistance genes in Enterococcus spp. from the last century reflects multiple pollution and genetic exchange among phyla from overlapping ecosystems

Andreia Rebelo et al.

Summary: The study investigated the presence of genes conferring tolerance to arsenic, mercury, and copper among Enterococcus, suggesting their potential as bioindicators for metal polluted environments. Different variants of metal tolerance genes were commonly found in food chains or humans and shared with other bacterial taxa. Enterococcus faecium and Enterococcus faecalis were identified as promising model organisms for future projects aiming at identifying and quantifying bioindicators of metal pollution caused by anthropogenic activities.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

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Article Infectious Diseases