Journal
ADVANCED MATERIALS
Volume 27, Issue 34, Pages 5080-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201501557
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Funding
- Exploratory Research for Advanced Technology of Japan Science and Technology Agency (JST-ERATO)
- Japanese Society for the Promotion of Science [26820361]
- Grants-in-Aid for Scientific Research [26820361] Funding Source: KAKEN
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A nanocarrier-integrated bottom-up method is a promising strategy for advanced drug-release systems. Self-assembled nanogels, which are one of the most beneficial nanocarriers for drug-delivery systems, are tectonically integrated to prepare nanogel-crosslinked (NanoClik) microspheres. NanoClik microspheres consisting of nanogel-derived structures (observed by STED microscopy) release drug-loaded nanogels after hydrolysis, resulting in successful sustained drug delivery in vivo.
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