In vitro egg maturation and in vitro fertilization-an idea whose time has come?

In vitro maturation of oocytes before their use in assisted reproduction has proved to be difficult and relatively unsuccessful despite a long history of attempts. Recent understanding of natural oocyte maturation, advances in culture media, and improved clinical approaches offer opportunities for a wider use of this technology in human in vitro fertilization. ((c) 2023 by American Society for Reproductive Medicine.)

Automated summary

Despite previous difficulties, recent advancements in understanding natural oocyte maturation, culture media, and clinical approaches have increased the potential for a wider use of in vitro maturation in human IVF.