4.6 Review

Magnetic nanoparticles: multifunctional tool for cancer therapy

Journal

EXPERT OPINION ON DRUG DELIVERY
Volume 20, Issue 2, Pages 189-204

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/17425247.2023.2166484

Keywords

Cancer; chemotherapy; gene therapy; hyperthermia; immunotherapy; magnetic nanoparticles; radiotherapy

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Cancer, with its high mortality rates, requires new therapeutic possibilities with enhanced benefits. Magnetic nanoparticles have shown substantial progress in cancer treatment, employing chemo-, immuno-, gene-, and radiotherapy along with hyperthermia.
IntroductionCancer has one of the highest mortality rates globally. The traditional therapies used to treat cancer have harmful adverse effects. Considering these facts, researchers have explored new therapeutic possibilities with enhanced benefits. Nanoparticle development for cancer detection, in addition to therapy, has shown substantial progress over the past few years.Area coveredHerein, the latest research regarding cancer treatment employing magnetic nanoparticles (MNPs) in chemo-, immuno-, gene-, and radiotherapy along with hyperthermia is summarized, in addition to their physio-chemical features, advantages, and limitations for clinical translation have also been discussed.Expert opinionMNPs are being extensively investigated and developed into effective modules for cancer therapy. They are highly functional tools aimed at cancer therapy owing to their excellent superparamagnetic, chemical, biocompatible, physical, and biodegradable properties.

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