Related references
Note: Only part of the references are listed.The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism
Hassan Choucair et al.
CANCER LETTERS (2022)
Mitochondria-targeting multi-metallic ZnCuO nanoparticles and IR780 for efficient photodynamic and photothermal cancer treatments
Hima Bindu Ruttala et al.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2021)
Carbon Chain Length Modulates MDA-MB-231 Breast Cancer Cell Killing Mechanisms by Mitochondrially Targeted Aryl-Urea Fatty Acids
Michael Murray et al.
CHEMMEDCHEM (2020)
Aryl urea substituted fatty acids: a new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter
Tristan Rawling et al.
CHEMICAL SCIENCE (2020)
Aryl-urea fatty acids that activate the p38 MAP kinase and down-regulate multiple cyclins decrease the viability of MDA-MB-231 breast cancer cells
Yassir Al-Zubaidi et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Carboxylate Analogues of Aryl-Urea-Substituted Fatty Acids That Target the Mitochondria in MDA-MB-231 Breast Cancer Cells to Promote Cell Death
Nooshin Koolaji et al.
CHEMMEDCHEM (2018)
A Novel Arylurea Fatty Acid That Targets the Mitochondrion and Depletes Cardiolipin To Promote Killing of Breast Cancer Cells
Tristan Rawling et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Polyunsaturated fatty acid-based targeted nanotherapeutics to enhance the therapeutic efficacy of docetaxel
Thiruganesh Ramasamy et al.
DRUG DELIVERY (2017)
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling
Martin D. Brand
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Anti-tumor activities of lipids and lipid analogues and their development as potential anticancer drugs
Michael Murray et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Synthetic ω-3 Epoxyfatty Acids As Antiproliferative and Proapoptotic Agents in Human Breast Cancer Cells
Herryawan Ryadi Eziwar Dyari et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications
John R. Falck et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
omega-3 Polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer
Weicang Wang et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2014)
Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health
Christophe Morisseau et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)
Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases
B. Meunier et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2013)
When ER stress reaches a dead end
Hery Urra et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Ulrich M. Zanger et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis
Guodong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mitochondrial Regulation of Cell Cycle and Proliferation
Valeria Gabriela Antico Arciuch et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
T. Verfaillie et al.
CELL DEATH AND DIFFERENTIATION (2012)
Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells
Marco Spinazzi et al.
NATURE PROTOCOLS (2012)
The ω-3 epoxide of eicosapentaenoic acid inhibits endothelial cell proliferation by p38 MAP kinase activation and cyclin D1/CDK4 down-regulation
Pei H. Cui et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Ras, ROS and Proteotoxic Stress: A Delicate Balance
Wanping Xu et al.
CANCER CELL (2011)
Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1
Natalia Mast et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
17(R),18(S)-Epoxyeicosatetraenoic Acid, a Potent Eicosapentaenoic Acid (EPA) Derived Regulator of Cardiomyocyte Contraction: Structure-Activity Relationships and Stable Analogues
John R. Falck et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress
Anne G. Lundemo et al.
LIPIDS IN HEALTH AND DISEASE (2011)
Impaired OXPHOS Complex III in Breast Cancer
Kjerstin M. Owens et al.
PLOS ONE (2011)
Mitochondrial proton and electron leaks
Martin Jastroch et al.
ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)
Targeting mitochondria for cancer therapy
Simone Fulda et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Targeting the endoplasmic reticulum-stress response as an anticancer strategy
Sandra J. M. Healy et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates Containing Epoxide Bioisosteres: Influence upon Vascular Relaxation and Soluble Epoxide Hydrolase Inhibition
J. R. Falck et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Mechanisms of Action of Eicosapentaenoic Acid in Bladder Cancer Cells In Vitro: Alterations in Mitochondrial Metabolism, Reactive Oxygen Species Generation and Apoptosis Induction
Alison Colquhoun
JOURNAL OF UROLOGY (2009)
Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450
Maude Fer et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Regulated externalization of phosphatidylserine at the cell surface - Implications for apoptosis
Krishnakumar Balasubramanian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia
PO Iversen et al.
CLINICAL CANCER RESEARCH (2006)
Application of heat-induced antigen retrieval to aldehyde-fixed fresh frozen sections
S Yamashita et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2005)
Ubiquinol cytochrome c reductase (UQCR-FS1) gene amplification in primary breast cancer core biopsy samples
Y Ohashi et al.
GYNECOLOGIC ONCOLOGY (2004)
Production of reactive oxygen species by mitochondria - Central role of complex III
Q Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells
KJ Tronstad et al.
CHEMISTRY & BIOLOGY (2003)
C11-BODIPY581/591, an oxidation-sensitive fluorescent lipid peroxidation probe:: (Micro)spectroscopic characterization and validation of methodology
GPC Drummen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status
KJ Tronstad et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
MS Fliss et al.
SCIENCE (2000)
Share Paper
