Infectious mononucleosis is associated with an increased incidence of Crohn's disease: results from a cohort study of 31 862 outpatients in Germany

Editorial Material Pharmacology & Pharmacy

Longitudinal Analysis Suggests Epstein--Barr as Cause of Multiple Sclerosis

[Anonymous]

CLINICAL PHARMACOLOGY & THERAPEUTICS (2022)

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Letter Gastroenterology & Hepatology

Prevalence of Hospitalization and Readmission in Patients with Inflammatory Bowel Diseases

Karel Kostev et al.

DIGESTIVE DISEASES AND SCIENCES (2022)

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Article Multidisciplinary Sciences

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis

Kjetil Bjornevik et al.

Summary: This study suggests that multiple sclerosis may be caused by Epstein-Barr virus, with no direct association with other viral infections. These findings provide clues to the primary cause of MS.

SCIENCE (2022)

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Article Neurosciences

Association Between Inflammatory Bowel Disease and Dementia: A Retrospective Cohort Study

Rebecca Zingel et al.

Summary: A study in German general practices found a positive association between IBD and dementia, with IBD patients showing a higher risk of developing dementia, especially in UC patients. The risk of dementia was increased by 1.22-fold in IBD patients, with UC patients having a 1.25-fold higher risk compared to CD patients.

JOURNAL OF ALZHEIMERS DISEASE (2021)

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Article Medicine, General & Internal

Clinical characteristics and sick leave associated with infectious mononucleosis in a real-world setting in Germany

Elisabeth J. Kap et al.

Summary: This study investigated the sick leave duration, diagnosis, treatment, and comorbidities of patients with infectious mononucleosis in a real-world setting in Germany. It found that the majority of patients were female, around 62% of patients took sick leave for an average of 20 days at the time of diagnosis, and only 1% were still on sick leave after 6 months.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

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Review Immunology

Sex Differences in Immunity to Viral Infections

Henning Jacobsen et al.

Summary: The ongoing COVID-19 pandemic has highlighted the sex-specific differences in immunity and outcomes following SARS-CoV-2 infection, with evidence suggesting a male bias in disease severity mediated by differential immune responses. While males are more susceptible to most viral infections, females possess immunological features that make them vulnerable to distinct immune-related disease outcomes. Sex chromosome complement, related genes, and sex steroids all play crucial roles in mediating these sex differences in immunity to viral infections.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Immunology

The Status and Prospects of Epstein-Barr Virus Prophylactic Vaccine Development

Cong Sun et al.

Summary: EBV is a common human herpesvirus associated with infectious mononucleosis, malignancies, and autoimmune diseases. Despite efforts to develop a prophylactic vaccine, there is currently no EBV vaccine in clinical use. Insights from the COVID-19 pandemic and global vaccine development offer opportunities for designing an effective prophylactic EBV vaccine to control worldwide EBV infection and associated diseases.

FRONTIERS IN IMMUNOLOGY (2021)

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Review Gastroenterology & Hepatology