4.6 Article

Association of buccal micronucleus cytome assay (BMNCyt) biomarkers with inorganic element concentration and genetic polymorphisms in welders

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

Buccal micronucleus cytome assay in children living in an area with low anthropogenic pressure: The EFFE.BIP study

Francesco Bagordo et al.

Summary: This study evaluated the micronucleus frequency in buccal cells of 6-8-year-old schoolchildren in a rural area of Southern Italy. The study found a positive association between micronucleus frequency and vehicular traffic, and a negative association with mother's high education level and physical exercise. The data on genotoxic effects in buccal cells could be considered as baseline levels in a pediatric population not exposed to environmental pollution.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2022)

Review Respiratory System

Occupational COPD-The most under-recognized occupational lung disease?

Nicola Murgia et al.

Summary: Chronic obstructive pulmonary disease (COPD) is primarily caused by smoking and occupational exposure, with the latter often being underestimated. Early diagnosis, identification of occupational causes, and collaborative treatment are crucial for preventing further decline in lung function and reducing the burden of COPD.

RESPIROLOGY (2022)

Article Biotechnology & Applied Microbiology

Cytokinesis-block micronucleus cytome (CBMN-CYT) assay and its relationship with genetic polymorphisms in welders

Grethel Leon-Mejia et al.

Summary: This study analyzed the impact of genetic polymorphisms on DNA damage caused by welding fumes exposure. The results showed significant differences in DNA damage markers among individuals with different genotypes, indicating the importance of individual susceptibility in occupational exposure to welding fumes.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2021)

Article Environmental Sciences

Cytokinesis-block micronucleus cytome (CBMN-CYT) assay biomarkers and telomere length analysis in relation to inorganic elements in individuals exposed to welding fumes

Milton Quintana-Sosa et al.

Summary: The study revealed that compounds released during welding activities cause oxidative stress, inflammation, and carcinogenic effects. Analysis showed higher concentrations of metals in the blood and urine of workers exposed to welding fumes, with significant correlations to cytotoxic and genotoxic markers.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021)

Article Oncology

Influence of Arg399Gln, Arg280His and Arg194Trp XRCC1 gene polymorphisms of Base Excision Repair pathway on the level of 8-oxo-guanine and risk of head and neck cancer in the Polish population

Jacek Kabzinski et al.

Summary: The study revealed that specific polymorphisms in the XRCC1 gene increase the risk of head and neck squamous cell carcinoma (HNSCC) and are correlated with levels of 8-oxo-guanine. The coexistence of these polymorphisms enhances the effect, and a high level of 8-oxoG may be a potential mechanism for how these polymorphisms modulate HNSCC risk.

CANCER BIOMARKERS (2021)

Article Biochemistry & Molecular Biology

Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?

Cheryl van de Wetering et al.

Summary: GSTs play crucial roles in susceptibility and progression of lung diseases, serving not only in detoxification, but also as important regulators of normal lung growth. Throughout life, the contribution of GSTs to (un)healthy lungs starts in utero and continues to impact.

REDOX BIOLOGY (2021)

Article Toxicology

Histopathological changes associated with exposure to metal welding fumes in some organs of Rattus norvegicus in Kano, Nigeria

A. Sani et al.

Summary: The study assessed the histopathological changes of organs in experimental animals exposed to welding fumes, resulting in damages and pathological changes in heart, kidney, liver, and lung tissues. Control and regulation should be imposed on exposure to welding fumes by metal workers.

TOXICOLOGY REPORTS (2021)

Article Public, Environmental & Occupational Health

Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk

Kjell Toren et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2020)

Article Environmental Sciences

DNA repair and metabolic gene polymorphisms affect genetic damage due to diesel engine exhaust exposure

Grethel Leon-Mejia et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020)

Review Pathology

Association of DNA repair gene polymorphisms with colorectal cancer risk and treatment outcomes

Fawaz N. Al-Shaheri et al.

EXPERIMENTAL AND MOLECULAR PATHOLOGY (2020)

Review Immunology

Alcohol use disorder and circulating cytokines: A systematic review and meta-analysis

Claire Adams et al.

BRAIN BEHAVIOR AND IMMUNITY (2020)

Article Toxicology

Welding fumes composition and their effects on blood heavy metals in albino rats

Ibrahim Lawal Abdullahi et al.

TOXICOLOGY REPORTS (2020)

Article Environmental Sciences

Cytotoxic and genotoxic effects in mechanics occupationally exposed to diesel engine exhaust

Grethel Leon-Mejia et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019)

Review Public, Environmental & Occupational Health

Welding fumes and lung cancer: a meta-analysis of case-control and cohort studies

Manoj Kumar Honaryar et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2019)

Article Oncology

RAD51 and XRCC3 Polymorphisms Are Associated with Increased Risk of Prostate Cancer

Maria Nowacka-Zawisza et al.

JOURNAL OF ONCOLOGY (2019)

Review Oncology

Magnesium and liver disease

Meixi Liu et al.

ANNALS OF TRANSLATIONAL MEDICINE (2019)

Article Biotechnology & Applied Microbiology

Assessment of DNA damage in welders using comet and micronucleus assays

Ildeniz Aksu et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2019)

Review Pharmacology & Pharmacy

Pathological Roles of Iron in Cardiovascular Disease

Motoi Kobayashi et al.

CURRENT DRUG TARGETS (2018)

Article Multidisciplinary Sciences

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Juan I. Garaycoechea et al.

NATURE (2018)

Review Biochemistry & Molecular Biology

Manganese homeostasis in the nervous system

Pan Chen et al.

JOURNAL OF NEUROCHEMISTRY (2015)

Article Environmental Sciences

Genetic damage in coal miners evaluated by buccal micronucleus cytome assay

Grethel Leon-Mejia et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2014)

Article Medicine, General & Internal

XRCC1 Polymorphisms and Risk of Papillary Thyroid Carcinoma in a Korean Sample

Ri A. Ryu et al.

JOURNAL OF KOREAN MEDICAL SCIENCE (2011)

Review Biotechnology & Applied Microbiology

Human population studies with the exfoliated buccal micronucleus assay: Statistical and epidemiological issues

Marcello Ceppi et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2010)

Article Oncology

Effect of processed and red meat on endogenous nitrosation and DNA damage

Annemiek M. C. P. Joosen et al.

CARCINOGENESIS (2009)

Article Biotechnology & Applied Microbiology

Genetic polymorphisms in XRCC1, OGG1, APE1 and XRCC3 DNA repair genes, ionizing radiation exposure and chromosomal DNA damage in interventional cardiologists

Maria Grazia Andreassi et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2009)

Article Biochemical Research Methods

Buccal micronucleus cytome assay

Philip Thomas et al.

NATURE PROTOCOLS (2009)

Article Biotechnology & Applied Microbiology

The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: The HUMN project perspective on current status and knowledge gaps

Nina Holland et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2008)

Article Genetics & Heredity

XRCC1 interactions with base excision repair DNA intermediates

Zhanna K. Nazarkina et al.

DNA REPAIR (2007)

Article Biochemistry & Molecular Biology

DNA repair gene XRCC3 polymorphisms and cancer risk: a meta-analysis of 48 case-control studies

Shizhong Han et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2006)

Article Environmental Sciences

Pulmonary responses to welding fumes: Role of metal constituents

JM Antonini et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2004)

Article Biochemistry & Molecular Biology

Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51

AL Forget et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Factors affecting the storage and excretion of toxic lipophilic xenobiotics

RJ Jandacek et al.

LIPIDS (2001)

Article Multidisciplinary Sciences

Does oxidative damage to DNA increase with age?

ML Hamilton et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Biochemistry & Molecular Biology

The OGG1 gene encodes a repair enzyme for oxidatively damaged DNA and is involved in human carcinogenesis

K Shinmura et al.

ANTIOXIDANTS & REDOX SIGNALING (2001)

Article Biotechnology & Applied Microbiology

XRCC3 is required for efficient repair of chromosome breaks by homologous recombination

MA Brenneman et al.

MUTATION RESEARCH-DNA REPAIR (2000)

Article Biotechnology & Applied Microbiology

Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response

H Autrup

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2000)