Journal
DISABILITY AND REHABILITATION
Volume 45, Issue 26, Pages 4359-4372Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09638288.2022.2152503
Keywords
Acquired brain injury (ABI); stroke; traumatic brain injury (TBI); subarachnoid haemorrhage (SAH); fatigue; cognition; outcome measures
Categories
Ask authors/readers for more resources
This study aimed to review and analyze the relationship between fatigue and cognitive impairment in ABI patients. The findings showed that sustained attention had stronger associations with fatigue, while weak associations were found with information processing, attention, memory, and executive function.
PurposeFatigue is a major symptom of ABI. Greater fatigue is associated with cognitive impairment. Our aim was to systematically review, describe and analyse the literature on the extent of this relationship.MethodsFive databases were searched from inception. Studies were included where: participants had a defined clinical diagnosis of ABI which included TBI, stroke or subarachnoid haemorrhage; a fatigue measure was included; at least one objective cognitive measure was used. Three reviewers individually identified studies and determined quality using the Quality Assessment Tool for Observational Cohort and Cross-sectional Studies.ResultsSixteen of the 412 identified studies, investigating the relationship between cognitive dysfunction and fatigue, comprising a total of 1,745 participants, were included. Quality ranged from fair to good. Meta-analysis found fatigue was significantly associated with an overall pattern of cognitive slowing on tasks of sustained attention. A narrative synthesis found weak associations with fatigue and information processing, attention, memory and executive function.ConclusionAnalysis found sustained attentional performance had stronger associations with fatigue after ABI. Whereas, weak associations were found between fatigue and information processing, attention and to some extent memory and executive function. More focused research on specific cognitive domains is needed to understand the mechanisms of fatigue.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available