Roux-en-Y Gastric Bypass Increases Glycemic Excursions During Pregnancy and Postpartum: A Prospective Cohort Study

Article Endocrinology & Metabolism

15. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes-2022

Summary: The American Diabetes Association (ADA) Standards of Medical Care in Diabetes provides guidelines and tools for diabetes care and evaluation of quality of care. The standards are updated by a multidisciplinary expert committee.

DIABETES CARE (2022)

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Review Surgery

Hypoglycemia in Pregnancies Following Gastric Bypass-a Systematic Review and Meta-analysis

Louise L. Stentebjerg et al.

Summary: This systematic review aimed to investigate the prevalence of hypoglycemia in pregnant women who underwent gastric bypass surgery and identify the risk factors associated with hypoglycemic events during pregnancy. The analysis of six included studies with a total of 330 participants revealed that 57.6% of women who had undergone gastric bypass surgery experienced hypoglycemia during pregnancy, as determined by oral glucose tolerance test and continuous glucose monitoring. However, no studies conducted mixed meal tests or reported on risk factors for hypoglycemia. Further research utilizing continuous glucose monitoring and mixed meal tests is needed to determine the extent of hypoglycemia in these women's everyday lives.

OBESITY SURGERY (2022)

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Article Endocrinology & Metabolism

Continuous Glucose Monitoring Metrics and Birth Weight: Informing Management of Type 1 Diabetes Throughout Pregnancy

Eleanor M. Scott et al.

Summary: This study analyzed data from 386 pregnant women with type 1 diabetes to determine the relationship between gestational weekly changes in CGM metrics and 24-h glucose profiles and infant birth weight. The results showed that normal birth weight is associated with lower mean CGM glucose concentration and higher time in range from early pregnancy, highlighting the importance of optimizing maternal glycemia early on.

DIABETES CARE (2022)

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Article Endocrinology & Metabolism

Symptomatic Hypoglycemia After Gastric Bypass: Incidence and Predictive Factors in a Cohort of 1,138 Consecutive Patients

Rebecca Bienvenot et al.

Summary: After Roux-en-Y gastric bypass, the incidence of severe postprandial hyperinsulinemic hypoglycemia with neuroglycopenic symptoms was higher than expected. Younger age, lower BMI after RYGB, maximal weight loss, and higher preoperative BMI were identified as independent predictive factors for higher risk of severe hypoglycemia.

OBESITY (2021)

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Article Surgery

Glucose Abnormalities and Inappropriate Weight Gain Predict Negative Pregnancy Outcomes After Gastric Bypass Surgery

H. Gohier et al.

Summary: A monocentric retrospective study analyzed 122 pregnancies after RYGB, finding that 73% of women had IG abnormalities, with risks of LGA, SGA, and preterm birth. Results showed LGA was associated with high glycemic time percentage and excessive maternal weight gain, while preterm birth was related to high glycemic time percentage and insufficient maternal weight gain.

OBESITY SURGERY (2021)

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Article Nutrition & Dietetics

Pregnancy after Bariatric Surgery: A Nested Case-Control Study of Risk Factors for Small for Gestational Age Babies in AURORA

Zainab Akhter et al.

Summary: Prior bariatric surgery is a significant risk factor for delivering small for gestational age (SGA) babies, with factors such as gestational weight gain, receiving nutritional advice, and weight management playing significant roles in influencing the risk of SGA babies.

NUTRIENTS (2021)

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Article Obstetrics & Gynecology