Imidazole and Derivatives Drugs Synthesis: A Review

Imidazoles have long held a special place in heterocyclic chemistry, and their derivatives have piqued interest in recent years due to their diverse chemistry and pharmacology features. Imidazole is a biologically and pharmaceutically important nitrogen-containing heterocyclic ring. As a result, researchers have been interested in imidazole molecules. For a century and a half, purine, histamine, and other natural compounds all contained the imidazole ring. A number of imidazole drugs have been prepared and marketed for the treatment of various diseases. In view of this, we herein report a detailed account of synthetic procedures for various imidazole drugs.

Automated summary

Imidazoles have significant importance in heterocyclic chemistry due to their diverse chemistry and pharmacology features. Imidazole is a biologically and pharmaceutically important nitrogen-containing heterocyclic ring. Therefore, researchers have shown interest in imidazole molecules. For the treatment of various diseases, several imidazole drugs have been synthesized and commercialized. In this report, we provide a detailed account of synthetic procedures for various imidazole drugs.