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Aishwarya Balap et al.
PHYTOTHERAPY RESEARCH (2017)
Inhibitory Effects of Multiple-Dose Treatment with Baicalein on the Pharmacokinetics of Ciprofloxacin in Rats
Youn-Hwan Hwang et al.
PHYTOTHERAPY RESEARCH (2017)
Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites
Xin Zhou et al.
XENOBIOTICA (2017)
Multidrug and toxin extrusion protein 1-mediated interaction of metformin and Scutellariae radix in rats
Sreymom Yim et al.
XENOBIOTICA (2017)
Investigation of the influence of glycyrrhizin on the pharmacokinetics of celastrol in rats using LC-MS and its potential mechanism
Guangkui Yan et al.
XENOBIOTICA (2017)
Effects of Caffeic Acid and Quercetin on In Vitro Permeability, Metabolism and In Vivo Pharmacokinetics of Melatonin in Rats: Potential for Herb-Drug Interaction
Snehasis Jana et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2017)
Glycyrrhetic acid, but not glycyrrhizic acid, strengthened entecavir activity by promoting its subcellular distribution in the liver via efflux inhibition
Qianying Chen et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents
Guannan Li et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Clinical risks of St John's Wort (Hypericum perforatum) co-administration
Samaneh Soleymani et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2017)
In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes
Xiaodan Hong et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
In vivo pharmacodynamic and pharmacokinetic interactions of Hibiscus sabdariffa calyces extracts with simvastatin
S. J. Showande et al.
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2017)
Herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide on pharmacokinetic and pharmacodynamic of naproxen in rats
Aishwarya Balap et al.
JOURNAL OF ETHNOPHARMACOLOGY (2017)
Modulation of Cytochrome P450, P-glycoprotein and Pregnane X Receptor by Selected Antimalarial HerbsImplication for Herb-Drug Interaction
Pius S. Fasinu et al.
MOLECULES (2017)
Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs)
Xu-Xin Zhang et al.
PHARMACEUTICAL BIOLOGY (2017)
The effects of triptolide on the pharmacokinetics of sorafenib in rats and its potential mechanism
Xianming Wang et al.
PHARMACEUTICAL BIOLOGY (2017)
Apigenin, a novel candidate involving herb-drug interaction (HDI), interacts with organic anion transporter 1 (OAT1)
Ting Wu et al.
PHARMACOLOGICAL REPORTS (2017)
A current update on phytochemistry, pharmacology and herb-drug interactions of Hypericum perforatum
Vinay S. Velingkar et al.
PHYTOCHEMISTRY REVIEWS (2017)
Pharmacokinetic herb-drug interaction of Xuesaitong dispersible tablet and aspirin after oral administration in blood stasis model rats
Guoliang Dai et al.
PHYTOMEDICINE (2017)
Enhanced Oral Bioavailability of Diltiazem by the Influence of Gallic Acid and Ellagic Acid in Male Wistar Rats: Involvement of CYP3A and P-gp Inhibition
Bhargavi Latha Athukuri et al.
PHYTOTHERAPY RESEARCH (2017)
Effects of Silymarin on Diabetes Mellitus Complications: A Review
Aline Maria Stolf et al.
PHYTOTHERAPY RESEARCH (2017)
Acute Calcineurin Inhibitor Nephrotoxicity Secondary to Turmeric Intake: A Case Report
A. Nayeri et al.
TRANSPLANTATION PROCEEDINGS (2017)
Effect of epigallocatechin-3-gallate, major ingredient of green tea, on the pharmacokinetics of rosuvastatin in healthy volunteers
Tae-Eun Kim et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2017)
Effect of Cinnamomum cassia on the Pharmacokinetics and Pharmacodynamics of Pioglitazone
Sandhya Mamindla et al.
CURRENT CLINICAL PHARMACOLOGY (2017)
Curcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme Activities
Suhaili Shamsi et al.
DRUG METABOLISM AND DISPOSITION (2017)
The effect of tripterygium glucoside tablet on pharmacokinetics of losartan and its metabolite EXP3174 in rats
Yongsheng Hu et al.
BIOMEDICAL CHROMATOGRAPHY (2017)
Impact of the Herbal Breviscapine on the Pharmacokinetics of - Simvastatin in Rats: The Involvement of CYP3A4[1]
Aixia Ju et al.
DRUG RESEARCH (2017)
Effects of Paeonia emodi on hepatic cytochrome P450 (CYP3A2 and CYP2C11) expression and pharmacokinetics of carbamazepine in rats
Mohammad Raish et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats
Harikesh Dubey et al.
INTEGRATIVE MEDICINE RESEARCH (2017)
Effect of Garlic, Gingko, and St. John's Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study
Jasmina Turkanovic et al.
DRUG METABOLISM AND DISPOSITION (2017)
Drug Metabolism in the Liver
Omar Abdulhameed Almazroo et al.
CLINICS IN LIVER DISEASE (2017)
Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease
Zahra Kiasalari et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)
The pharmacokinetics change of cefepime after Shuanghuanglian injection administration in subjects with the renal damage
Hao Chen et al.
DRUG AND CHEMICAL TOXICOLOGY (2016)
Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences
Enoche F. Oga et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2016)
Effect of Ginkgo Leaf Tablets on the Pharmacokinetics of Amlodipine in Rats
Rong Wang et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2016)
Salvia miltiorrhiza: A source for anti-Alzheimer's disease drugs
Xiu-Zhen Zhang et al.
PHARMACEUTICAL BIOLOGY (2016)
Effect of Resveratrol Treatment on the Pharmacokinetics of Diclofenac in Healthy Human Volunteers
Satish Kumar Bedada et al.
PHYTOTHERAPY RESEARCH (2016)
Rhubarb decreased the systemic exposure of cyclosporine, a probe substrate of P-glycoprotein and CYP 3A
Chung-Ping Yu et al.
XENOBIOTICA (2016)
Pharmacokinetic herb-drug interactions with traditional Chinese medicine: progress, causes of conflicting results and suggestions for future research
Bing-Liang Ma et al.
DRUG METABOLISM REVIEWS (2016)
Effects of the Chinese herbal formula Zuojin Pill on the pharmacokinetics of dextromethorphan in healthy Chinese volunteers with CYP2D6*10 genotype
Furong Qiu et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2016)
Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - A comprehensive review
Navaneethakrishnan Polachi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Effects of Jia-Wei-Xiao-Yao-San on the Peripheral and Lymphatic Pharmacokinetics of Paclitaxel in Rats
Mei-Ling Hou et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)
Herb-Drug Interaction: Effects of Relinqing, Granule on the Pharmacokinetics of Ciprofloxacin, Sulfamethoxazole, and Trimethoprim in Rats
Yuan Lu et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)
Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases
Hong Xin et al.
FOOD AND CHEMICAL TOXICOLOGY (2016)
Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb-drug interactions
Xu Wu et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2016)
Pharmacokinetic and pharmacodynamic herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide with etoricoxib after oral administration in rats
Aishwarya Balap et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
The effects of Chuanxiong on the pharmacokinetics of warfarin in rats after biliary drainage
Haigang Li et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Effects of salvianolic acid B and tanshinone IIA on the pharmacokinetics of losartan in rats by regulating the activities and expression of CYP3A4 and CYP2C9
Rong Wang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Mechanistic understanding of the effect of Dengzhan Shengmai capsule on the pharmacokinetics of clopidogrel in rats
Xinmeng Chen et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats
Chenrui Li et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2016)
Increased Systemic Exposure of Methotrexate by a Polyphenol-Rich Herb via Modulation on Efflux Transporters Multidrug Resistance-Associated Protein 2 and Breast Cancer Resistance Protein
Chung-Ping Yu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
In Vivo and in Vitro Study on Drug-Drug Interaction of Lovastatin and Berberine from Pharmacokinetic and HepG2 Cell Metabolism Studies
Hanming Cui et al.
MOLECULES (2016)
Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism
Hong Li et al.
PHARMACEUTICAL BIOLOGY (2016)
Effects of standardized Ginkgo biloba extract on the acquisition, retrieval and extinction of conditioned suppression: Evidence that short-term memory and long-term memory are differentially modulated
C. R. Zamberlam et al.
PHYSIOLOGY & BEHAVIOR (2016)
Pharmacokinetic and Pharmacodynamic Interaction of Boswellic Acids and Andrographolide with Glyburide in Diabetic Rats: Including Its PK/PD Modeling
Sujatha Samala et al.
PHYTOTHERAPY RESEARCH (2016)
Effect of Ginkgo Biloba Extract on the Pharmacokinetics and Metabolism of Clopidogrel in Rats
Ying Deng et al.
PHYTOTHERAPY RESEARCH (2016)
Effects of Silymarin, Glycyrrhizin, and Oxymatrine on the Pharmacokinetics of Ribavirin and Its Major Metabolite in Rats
Sha Liao et al.
PHYTOTHERAPY RESEARCH (2016)
In vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase (UGT) isoforms
Doyun Kim et al.
TOXICOLOGY LETTERS (2016)
Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone
Tore Bjerregaard Stage et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb-drug interactions on OATP1B3
Rongrong Jiang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Pharmacokinetic Interactions Between Herbal Medicines and Prescribed Drugs: Focus on Drug Metabolic Enzymes and Transporters
Qiang Meng et al.
CURRENT DRUG METABOLISM (2015)
Pharmacokinetic Interactions of Herbs with Cytochrome P450 and P-Glycoprotein
Hyun-Jong Cho et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)
Herb-drug interactions between Scutellariae Radix and mefenamic acid: Simultaneous investigation of pharmacokinetics, anti-inflammatory effect and gastric damage in rats
Sophia Yui Kau Fong et al.
JOURNAL OF ETHNOPHARMACOLOGY (2015)
Pharmacokinetic interaction between Kaempferia parviflora extract and sildenafil in rats
Catheleeya Mekjaruskul et al.
JOURNAL OF NATURAL MEDICINES (2015)
SLC transporters as therapeutic targets: emerging opportunities
Lawrence Lin et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Assessment of Pharmacodynamic and Pharmacokinetic Interaction of Aqueous Extract of Cassia auriculata L. and Metformin in Rats
Hemnath Elango et al.
PHARMACOGNOSY MAGAZINE (2015)
Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy
Renata Silva et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Pharmacological Effects of Glycyrrhiza spp. and Its Bioactive Constituents: Update and Review
Hossein Hosseinzadeh et al.
PHYTOTHERAPY RESEARCH (2015)
Modulation of Cytochrome P450 Activity by 18-Glycyrrhetic Acid and its Consequence on Buspirone Pharmacokinetics in Rats
Sang-Bum Kim et al.
PHYTOTHERAPY RESEARCH (2015)
DNA-protective activities of hyperforin and aristoforin
A. Sevcovicova et al.
TOXICOLOGY IN VITRO (2015)
Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice
Ling-Lei Kong et al.
SCIENTIFIC REPORTS (2015)
Chemical diversity of ginseng saponins from Panax ginseng
Byong-Kyu Shin et al.
JOURNAL OF GINSENG RESEARCH (2015)
The physiological role of drug transporters
Yu Liang et al.
PROTEIN & CELL (2015)
Organic cation transporter-mediated drug-drug interaction potential between berberine and metformin
Mihwa Kwon et al.
ARCHIVES OF PHARMACAL RESEARCH (2015)
The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype
Christoph Markert et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2015)
Effect of scutellarin on the metabolism and pharmacokinetics of clopidogrel in rats
Xinmeng Chen et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2015)
Potential herb-drug interaction in the prevention of cardiovascular diseases during integrated traditional and western medicine treatment
Wang Xiao-long
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2015)
The effects of Andrographis paniculata (Burm. f.) Nees extract and diterpenoids on the CYP450 isoforms' activities, a review of possible herb-drug interaction risks
Mei Lan Tan et al.
DRUG AND CHEMICAL TOXICOLOGY (2015)
t Herb-drug interaction between irinotecan and psoralidin-containing herbs
Xi-Shan Zhang et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2015)
Effect of Dehusked Garcinia kola Seeds on the Overall Pharmacokinetics of Quinine in Healthy Nigerian Volunteers
Sharon I. Igbinoba et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Comparative inhibitory potential of selected dietary bioactive polyphenols, phytosterols on CYP3A4 and CYP2D6 with fluorometric high-throughput screening
Thangavel Mahalingam Vijayakumar et al.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2015)
Allicin induces apoptosis of the MGC-803 human gastric carcinoma cell line through the p38 mitogen-activated protein kinase/caspase-3 signaling pathway
Xuecheng Zhang et al.
MOLECULAR MEDICINE REPORTS (2015)
Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs
Fahad I. Al-Jenoobi et al.
PHARMACEUTICAL BIOLOGY (2015)
Pharmacokinetics of cisplatin in the absence or presence of Zengmian Yiliu granules (a traditional Chinese medicine compound) in rats determined via ICP-MS: An investigation on drug-herb interactions
Qin-Hua Zhang et al.
PHARMACEUTICAL BIOLOGY (2015)
Effect of kanglaite on rat cytochrome P450
Xiaoxiang Du et al.
PHARMACEUTICAL BIOLOGY (2015)
Pre-treatment with puerarin affects pharmacokinetics of warfarin, but not clopidogrel, in experimental rats
Liu An-Chang et al.
CHINESE JOURNAL OF NATURAL MEDICINES (2015)
Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future
Susan P. C. Cole
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 54 (2014)
In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2
Min Song et al.
ARCHIVES OF PHARMACAL RESEARCH (2014)
Effect of Sophora flavescens on the pharmacokinetics of carbamazepine in rats
Lei Shi et al.
ARCHIVES OF PHARMACAL RESEARCH (2014)
Evaluation of the transporter-mediated herb-drug interaction potential of DA-9801, a standardized dioscorea extract for diabetic neuropathy, in human in vitro and rat in vivo
Im-Sook Song et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
St. John's Wort Reduces Beta-Amyloid Accumulation in a Double Transgenic Alzheimer's Disease Mouse Model-Role of P-Glycoprotein
Anja Brenn et al.
BRAIN PATHOLOGY (2014)
The effect of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of cilostazol and its active metabolites in healthy Korean subjects
Ho-Sook Kim et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2014)
Effects of triptolide on the pharmacokinetics of cyclophosphamide in rats: A possible role of CytochromeP3A4 inhibition
Zhang Xi-feng et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2014)
The Effect of St John's Wort on the Pharmacokinetics of Docetaxel
Andrew K. L. Goey et al.
CLINICAL PHARMACOKINETICS (2014)
Effect of silibinin on the pharmacokinetics of nitrendipine in rabbits
Swathi Voruganti et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2014)
Ginsenoside Rb1 improves postoperative fatigue syndrome by reducing skeletal muscle oxidative stress through activation of the PI3K/Akt/Nrf2 pathway in aged rats
Cheng-Le Zhuang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Effects of Danshen Ethanol Extract on the Pharmacokinetics of Fexofenadine in Healthy Volunteers
Furong Qiu et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
Pharmacokinetic interaction between febuxostat and morin in rats
Kapendra Sahu et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2014)
Thermal stability of ginkgolic acids from Ginkgo biloba and the effects of ginkgol C17:1 on the apoptosis and migration of SMMC7721 cells
Xiao-Ming Yang et al.
FITOTERAPIA (2014)
Influence of St. John's wort on the steady-state pharmacokinetics and metabolism of bosentan
Christoph Markert et al.
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS (2014)
Multifaceted interaction of the traditional Chinese medicinal herb Schisandra chinensis with cytochrome P450-mediated drug metabolism in rats
Baolian Wang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Induction of liver cytochrome P450s by Danshen-Gegen formula is the leading cause for its pharmacokinetic interactions with warfarin
Zhen Zhang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Development of a microdialysis system to monitor lamivudine in blood and liver for the pharmacokinetic application in herbal drug interaction and the gene expression in rats
Chia-Ming Lu et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2014)
Herb-drug Pharmacokinetic Interaction between Carica Papaya Extract and Amiodarone in Rats
Marcio Rodrigues et al.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2014)
Da-Chaihu-Tang alters the pharmacokinetics of nifedipine in rats and a treatment regimen to avoid this
Ju-Xiu He et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2014)
Reversion of P-glycoprotein-mediated multidrug resistance by diallyl trisulfide in a human osteosarcoma cell line
Zhiyong Wang et al.
ONCOLOGY REPORTS (2014)
Evaluation of Inhibitory Effects of Caffeic acid and Quercetin on Human Liver Cytochrome P450 Activities
Himanshu Rastogi et al.
PHYTOTHERAPY RESEARCH (2014)
In Vitro and In Vivo Evaluation of the Effect of Puerarin on Hepatic Cytochrome P450-Mediated Drug Metabolism
Sang-Bum Kim et al.
PLANTA MEDICA (2014)
Pharmacokinetic Compatibility of Ginsenosides and Schisandra Lignans in Shengmai-san: From the Perspective of P-Glycoprotein
Yan Liang et al.
PLOS ONE (2014)
Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: Herb-drug interactions mediated via P-gp
Xue Li et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Antidepressant-like activity of adhyperforin, a novel constituent of Hypericum perforatum L.
Jingwei Tian et al.
SCIENTIFIC REPORTS (2014)
The Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 Activity
Marina Kawaguchi-Suzuki et al.
DRUG METABOLISM AND DISPOSITION (2014)
Herb-Drug Interactions: Challenges and Opportunities for Improved Predictions
Scott J. Brantley et al.
DRUG METABOLISM AND DISPOSITION (2014)
Pungent ginger components modulates human cytochrome P450 enzymes in vitro
Mian Li et al.
ACTA PHARMACOLOGICA SINICA (2013)
Interaction of Rhubarb and Methotrexate in Rats: In Vivo and Ex Vivo Approaches
Chi-Sheng Shia et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2013)
Effects of Zingiber officinale on the Plasma Pharmacokinetics and Lung Penetrations of Ciprofloxacin and Isoniazid
Sunday O. Nduka et al.
AMERICAN JOURNAL OF THERAPEUTICS (2013)
Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients
Christian Ude et al.
CLINICAL PHARMACOKINETICS (2013)
The Mechanisms Responsible for Garlic - Drug Interactions and their In Vivo Relevance
Katja Berginc et al.
CURRENT DRUG METABOLISM (2013)
Pharmacokinetic drug interactions involving Ginkgo biloba
Matthias Unger
DRUG METABOLISM REVIEWS (2013)
Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats
Xin Tian et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)
Opposite Effects of Single-Dose and Multidose Administration of the Ethanol Extract of Danshen on CYP3A in Healthy Volunteers
Furong Qiu et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)
Pharrnacokinetic properties, potential herb-drug interactions and acute toxicity of oral Rhizoma coptidis alkaloids
Bing-Liang Ma et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)
Inhibitory effects of gypenosides on seven human cytochrome P450 enzymes in vitro
Min He et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Selective inhibitory effects of mollugin on CYP1A2 in human liver microsomes
Heeyeon Kim et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Capsaicin pretreatment increased the bioavailability of cyclosporin in rats: Involvement of P-glycoprotein and CYP 3A inhibition
Xue-jia Zhai et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Increase in antioxidant and anticancer effects of ginsenoside Re-lysine mixture by Mail lard reaction
Noriko Yamabe et al.
FOOD CHEMISTRY (2013)
Potential Risk of Mulberry-Drug Interaction: Modulation on P-Glycoprotein and Cytochrome P450 3A
Pei-Wen Hsu et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)
Glycyrrhizic acid (GCA) as 11β-hydroxysteroid dehydrogenase inhibitor exerts protective effect against glucocorticoid-induced osteoporosis
Elvy Suhana Mohd Ramli et al.
JOURNAL OF BONE AND MINERAL METABOLISM (2013)
Liquorice, a unique guide drug of traditional Chinese medicine: A review of its role in drug interactions
Xiaoying Wang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2013)
Astragaloside IV inhibited the activity of CYP1A2 in liver microsomes and influenced theophylline pharmacokinetics in rats
Yan-Hui Zhang et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2013)
Herb-drug pharmacokinetic interaction of artificial calculus bovis with diclofenac sodium and chlorpheniramine maleate in rats
Can Peng et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2013)
Herb-Drug Interaction of Epimedium sagittatum (Sieb. et Zucc.) Maxim Extract on the Pharmacokinetics of Sildenafil in Rats
Thomas Y. Hsueh et al.
MOLECULES (2013)
Effect of long-term co-administration of Wuzhi tablet (Schisandra sphenanthera extract) and prednisone on the pharmacokinetics of tacrolimus
Xiao-Ling Qin et al.
PHYTOMEDICINE (2013)
In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein
Yan Liang et al.
PHYTOMEDICINE (2013)
Effects of green tea extract and (-)-epigallocatechin-3-gallate on pharmacokinetics of nadolol in rats
S. Misaka et al.
PHYTOMEDICINE (2013)
Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Cyclosporin A in Rats
Xin-ping Xue et al.
PHYTOTHERAPY RESEARCH (2013)
Effects of Lepidium sativum, Nigella sativa and Trigonella foenum-graceum on Phenytoin Pharmacokinetics in Beagle Dogs
Khalid M. Alkharfy et al.
PHYTOTHERAPY RESEARCH (2013)
Curcumin Alters the Pharmacokinetics of Warfarin and Clopidogrel in Wistar Rats but Has No Effect on Anticoagulation or Antiplatelet Aggregation
An-Chang Liu et al.
PLANTA MEDICA (2013)
Concentration-Dependent Inhibitory Effect of Baicalin on the Plasma Protein Binding and Metabolism of Chlorzoxazone, a CYP2E1 Probe Substrate, in Rats In Vitro and In Vivo
Na Gao et al.
PLOS ONE (2013)
Pharmacokinetic Interaction between Losartan and Rhodiola rosea in Rabbits
M. Spanakis et al.
PHARMACOLOGY (2013)
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Ulrich M. Zanger et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1
Yue-Ming Wang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Effects of single or repeated silymarin administration on pharmacokinetics of risperidone and its major metabolite, 9-hydroxyrisperidone in rats
Kyoung Sin Lee et al.
XENOBIOTICA (2013)
Assessment of a pharmacokinetic and pharmacodynamic interaction between simvastatin and Ginkgo biloba extracts in healthy subjects
Ling-Ling Dai et al.
XENOBIOTICA (2013)
The Potential of Sutherlandia frutescens for Herb-Drug Interaction
Pius S. Fasinu et al.
DRUG METABOLISM AND DISPOSITION (2013)
Identification and Characterization of Psoralen and Isopsoralen as Potent CYP1A2 Reversible and Time-Dependent Inhibitors in Human and Rat Preclinical Studies
Xiao-Mei Zhuang et al.
DRUG METABOLISM AND DISPOSITION (2013)
Effects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in Rats
Hua Wei et al.
DRUG METABOLISM AND DISPOSITION (2013)
Transporters and Drug-Drug Interactions: Important Determinants of Drug Disposition and Effects
Joerg Koenig et al.
PHARMACOLOGICAL REVIEWS (2013)
Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides
Kathleen Koeck et al.
DRUG METABOLISM AND DISPOSITION (2013)
Herb-Drug Interaction of 50 Chinese Herbal Medicines on CYP3A4 Activity in Vitro and in Vivo
Li-Heng Pao et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2012)
Effect of Ginkgo Biloba on the Pharmacokinetics of Raltegravir in Healthy Volunteers
Maren Blonk et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Herb-Drug Interaction between Echinacea purpurea and Etravirine in HIV-Infected Patients
Jose Molto et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Pre-treatment with Curcumin Enhances Plasma Concentrations of Losartan and Its Metabolite EXP3174 in Rats
An-Chang Liu et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2012)
Repeated dosing of piperine induced gene expression of P-glycoprotein via stimulated pregnane-X-receptor activity and altered pharmacokinetics of diltiazem in rats
Fu Qiang et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2012)
A study about drug combination therapy of Schisandra sphenanthera extract and Rapamycin in healthy subjects
Ruidong Li et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2012)
Roles of UDP-Glucuronosyltransferases in Phytochemical Metabolism of Herbal Medicines and the Associated Herb-Drug Interactions
Li Li et al.
CURRENT DRUG METABOLISM (2012)
Food-drug Interaction of Tacrolimus with Pomelo, Ginger, and Turmeric Juice in Rats
Kanoko Egashira et al.
DRUG METABOLISM AND PHARMACOKINETICS (2012)
Repeated administration of berberine inhibits cytochromes P450 in humans
Ying Guo et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Effect of dose and dosage interval on the oral bioavailability of docetaxel in combination with a curcumin self-emulsifying drug delivery system (SEDDS)
Yi-Dong Yan et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2012)
Inhibition of hepatic uptake transporters by flavonoids
Kathrin Mandery et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Herb-Drug Interaction of Paullinia cupana (Guarana) Seed Extract on the Pharmacokinetics of Amiodarone in Rats
Marcio Rodrigues et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012)
Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in rats
Jung-woo Chae et al.
FOOD AND CHEMICAL TOXICOLOGY (2012)
St John's wort greatly decreases the plasma concentrations of oral S-ketamine
Marko A. Peltoniemi et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2012)
Pharmacokinetic interaction of garlic and atorvastatin in dyslipidemic rats
G. Dilip Reddy et al.
INDIAN JOURNAL OF PHARMACOLOGY (2012)
Influence of Panax ginseng on Cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) Activity in Healthy Participants
Christine Y. Malati et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2012)
P-glycoprotein mediated efflux in Caco-2 cell monolayers: The influence of herbals on digoxin transport
Enoche F. Oga et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Andrographolide inhibits the expression and metabolic activity of cytochrome P450 3A4 in the modified Caco-2 cells
Feng Qiu et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Pharmacokinetic and pharmacodynamic interaction of Danshen-Gegen extract with warfarin and aspirin
Limin Zhou et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Effect of decursin on the pharmacokinetics of theophylline and its metabolites in rats
Jung-woo Chae et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Effects of HuangKui capsules on glibenclamide pharmacokinetics in rats
Zixiu Liu et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Mechanism of drug interaction between a Kampo medicine, byakkokaninjinto, and tetracycline in rats
Kotaro Hitoshi et al.
JOURNAL OF INFECTION AND CHEMOTHERAPY (2012)
In-vitro metabolism of glycyrrhetinic acid by human and rat liver microsomes and its interactions with six CYP substrates
Kai Zhao et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2012)
Time-course effects of St John's wort on the pharmacokinetics of cyclosporine in dogs
K. Fukunaga et al.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS (2012)
Capsaicin induces CYP3A4 expression via pregnane X receptor and CCAAT/enhancer-binding protein β activation
Eun Hee Han et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2012)
Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2,3,5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes
Ru Feng et al.
PHYTOMEDICINE (2012)
Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice
Yuko Taki et al.
PHYTOMEDICINE (2012)
Effects of Panax notoginseng Saponins on the Activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in Rats In Vivo
Rui Liu et al.
PHYTOTHERAPY RESEARCH (2012)
Drug-drug Interactions between Ketoconazole and Berberine in Rats: Pharmacokinetic Effects Benefit Pharmacodynamic Synergism
Yanmi Zhou et al.
PHYTOTHERAPY RESEARCH (2012)
Scutellarin Inhibits Cytochrome P450 Isoenzyme 1A2 (CYP1A2) in Rats
Tun-Yu Jian et al.
PHYTOTHERAPY RESEARCH (2012)
Limitations of In Vitro Assessments of the Drug Interaction Potential of Botanical Supplements
John S. Markowitz et al.
PLANTA MEDICA (2012)
Co-administration of piperine and docetaxel results in improved anti-tumor efficacy via inhibition of CYP3A4 activity
Peter Makhov et al.
PROSTATE (2012)
A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats
Ying-Chang Chi et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Effect of genistein on the activities of cytochrome P450 3A and P-glycoprotein in Chinese healthy participants
C. -Q. Xiao et al.
XENOBIOTICA (2012)
Influence of capsaicin on fluctuation of digoxin pharmacokinetics in lipopolysaccharide-treated rats
Ryuji Kato et al.
XENOBIOTICA (2012)
Effects of Phyllanthus amarus on the pharmacokinetics of midazolam and cytochrome P450 activities in rats
Theerada Taesotikul et al.
XENOBIOTICA (2012)
Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices
Cheng-Xian Guo et al.
XENOBIOTICA (2012)
Insecticidal, antimicrobial and antioxidant activities of bulb extracts of Allium sativum
Balaji Meriga et al.
ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE (2012)
An overview of the evidence and mechanisms of herb-drug interactions
Pius S. Fasinu et al.
FRONTIERS IN PHARMACOLOGY (2012)
Effects of Baicalein on the Pharmacokinetics of Tamoxifen and its Main Metabolite, 4-Hydroxytamoxifen, in Rats: Possible Role of Cytochrome P450 3A4 and P-glycoprotein inhibition by Baicalein
Cheng Li et al.
ARCHIVES OF PHARMACAL RESEARCH (2011)
Effects of Quercetin on the Bioavailability of Doxorubicin in Rats: Role of CYP3A4 and P-gp Inhibition by Quercetin
Jun-Shik Choi et al.
ARCHIVES OF PHARMACAL RESEARCH (2011)
Effect of Diallyl Trisulfide on the Pharmacokinetics of Dipyridamole in Rats
Yue Wang et al.
ARCHIVES OF PHARMACAL RESEARCH (2011)
Development of a Whole-Cell Screening System for Evaluation of the Human CYP1A2-Mediated Metabolism
Chih-Chieh Chu et al.
BIOTECHNOLOGY AND BIOENGINEERING (2011)
The Pregnane X Receptor Agonist St John's Wort Has No Effects on the Pharmacokinetics and Pharmacodynamics of Repaglinide
Lan Fan et al.
CLINICAL PHARMACOKINETICS (2011)
Update on the Chemopreventive Effects of Ginger and its Phytochemicals
Manjeshwar Shrinath Baliga et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2011)
Herb-drug Interactions Involving Drug Metabolizing Enzymes and Transporters
Chang-Xiao Liu et al.
CURRENT DRUG METABOLISM (2011)
Clinical Herbal Interactions with Conventional Drugs: From Molecules to Maladies
X-W Chen et al.
CURRENT MEDICINAL CHEMISTRY (2011)
The P-glycoprotein multidrug transporter
Frances J. Sharom
ESSAYS IN BIOCHEMISTRY: ABC TRANSPORTERS (2011)
The effect of herbal medicine danshensu and ursolic acid on pharmacokinetics of rosuvastatin in rats
Jin-Hua Wen et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2011)
Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats
Syed Mohammed Basheeruddin Asdaq et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2011)
Inhibitory effect of tanshinones on rat CYP3A2 and CYP2C11 activity and its structure-activity relationship
Xin Wang et al.
FITOTERAPIA (2011)
Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb-drug interactions
Joo Hyun Lee et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)
Physiologically Based Pharmacokinetic Modeling: Methodology, Applications, and Limitations with a Focus on Its Role in Pediatric Drug Development
Feras Khalil et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
The Effect of St John's Wort on the Pharmacodynamic Response of Clopidogrel in Hyporesponsive Volunteers and Patients: Increased Platelet Inhibition by Enhancement of CYP3A4 Metabolic Activity
Wei C. Lau et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2011)
Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice
Ying Guo et al.
JOURNAL OF ETHNOPHARMACOLOGY (2011)
Effect of Diallyl Trisulfide on the Pharmacokinetics of Nifedipine in Rats
Yue Wang et al.
JOURNAL OF FOOD SCIENCE (2011)
In Vitro Inhibition of Huanglian [Rhizoma coptidis (L.)] and its Six Active Alkaloids on Six Cytochrome P450 Isoforms in Human Liver Microsomes
Yong-Long Han et al.
PHYTOTHERAPY RESEARCH (2011)
Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line
Rong Zhang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Imatinib and Panax ginseng: A Potential Interaction Resulting in Liver Toxicity
Naveen Bilgi et al.
ANNALS OF PHARMACOTHERAPY (2010)
Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1
Kathrin Mandery et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Effects of Mace and Nutmeg on Human Cytochrome P450 3A4 and 2C9 Activity
Yuka Kimura et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2010)
Effect of danshen extract on the activity of CYP3A4 in healthy volunteers
Furong Qiu et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Deoxyelephantopin, a novel multifunctional agent, suppresses mammary tumour growth and lung metastasis and doubles survival time in mice
Chi-Chang Huang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Molecular Modeling of Cytochrome P450 and Drug Metabolism
Jing-Fang Wang et al.
CURRENT DRUG METABOLISM (2010)
Regioselective Glucuronidation of Tanshinone IIa after Quinone Reduction: Identification of Human UDP-Glucuronosyltransferases, Species Differences, and Interaction Potential
Qiong Wang et al.
DRUG METABOLISM AND DISPOSITION (2010)
Garlic Flavonoids and Organosulfur Compounds: Impact on the Hepatic Pharmacokinetics of Saquinavir and Darunavir
Katja Berginc et al.
DRUG METABOLISM AND PHARMACOKINETICS (2010)
Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects
Xiao-Cong Zuo et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Effect of glycyrrhizin on the activity of CYP3A enzyme in humans
Jiang-Hua Tu et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2010)
St John's wort greatly reduces the concentrations of oral oxycodone
Tuija H. Nieminen et al.
EUROPEAN JOURNAL OF PAIN (2010)
Herb-drug pharmacokinetic interactions reviewed
Clemence Tarirai et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2010)
Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506)
Xiao Ling Qin et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2010)
In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes-Glutathione Transferases (GSTs)
Juzaili Azizi et al.
MOLECULES (2010)
The Effects of Salvianolic Acid B from Radix Salvia Miltiorrhizae on the Oral Pharmacokinetics of Metoprolol and Metoprolol Acid in Rats
Ren-zhong Wan et al.
PHYTOTHERAPY RESEARCH (2010)
Milk Thistle in Liver Diseases: Past, Present, Future
Ludovico Abenavoli et al.
PHYTOTHERAPY RESEARCH (2010)
Effect of St. John's wort supplementation on the pharmacokinetics of bupropion in healthy male Chinese volunteers
H. -P. Lei et al.
XENOBIOTICA (2010)
Effect of glycyrrhizin on CYP2C19 and CYP3A4 activity in healthy volunteers with different CYP2C19 genotypes
J. -H. Tu et al.
XENOBIOTICA (2010)
The potential for interaction of hydrochlorothiazide with garlic in rats
Syed Mohammed Basheeruddin Asdaq et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men
Anna Lundahl et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Cytochrome P450 Enzymes and the Heart
Ketul R. Chaudhary et al.
IUBMB LIFE (2009)
Glycyrrhizin and Licorice Significantly Affect the Pharmacokinetics of Methotrexate in Rats
Shiuan-Pey Lin et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)
Biotechnological synthesis of drug metabolites using human cytochrome P450 isozymnes heterologously expressed in fission yeast
Frank T. Peters et al.
BIOANALYSIS (2009)
Xenobiotic metabolizing enzymes in the central nervous system: Contribution of cytochrome P450 enzymes in normal and pathological human brain
Fabien Dutheil et al.
BIOCHIMIE (2008)
Effect of danshen extract on pharmacokinetics of theophylline in healthy volunteers
Furong Qiu et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide
H. Xu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals
Tomohiro Nabekura et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)
Cytochrome P450 and chemical toxicology
F. Peter Guengerich
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes
Furong Qiu et al.
DRUG METABOLISM AND DISPOSITION (2008)
Clinical assessment of CYP2D6-mediated herb-drug interactions in humans:: Effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea
Bill J. Gurley et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2008)
Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: Comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxiin pharmacokinetics
Bill J. Gurley et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2008)
Effect of silymarin supplement on the pharmacokinetics of rosuvastatin
Jian Wei Deng et al.
PHARMACEUTICAL RESEARCH (2008)
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
S. -F. Zhou
XENOBIOTICA (2008)
Pharmacovigilance: Effects of herbal components on human drugs interactions involving Cytochrome P450
Akansha Saxena et al.
BIOINFORMATION (2008)
Cytochrome P3A4 inhibitors and other constituents of Fibraurea tinctoria
Chung-Ren Su et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Effects of herbal products and their constituents on human cytochrome P4502E1 activity
Gregory M. Raner et al.
FOOD AND CHEMICAL TOXICOLOGY (2007)
Silybin is metabolized by cytochrome P4502C8 in vitro
Petra Jancova et al.
DRUG METABOLISM AND DISPOSITION (2007)
The effect of silymarin on oral nifedipine pharmacokinetics
Uwe Fuhr et al.
PLANTA MEDICA (2007)
Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues
Ivan Bieche et al.
PHARMACOGENETICS AND GENOMICS (2007)
Induction of intestinal P-glycoprotein by St John's wort reduces the oral bioavailability of talinolol
U. I. Schwarz et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)
Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues
Tracy C. DeLozier et al.
DRUG METABOLISM AND DISPOSITION (2007)
In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study
Luisella Verotta et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
The-50G > T polymorphism in the promoter of the CYP2J2 gene in coronary heart disease: The Ludwigshafen risk and cardiovascular health study
Michael M. Hoffmann et al.
CLINICAL CHEMISTRY (2007)
A primer on the mechanics of P-glycoprotein the multidrug transporter
M. Hennessy et al.
PHARMACOLOGICAL RESEARCH (2007)
Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters
Supratim Choudhuri et al.
INTERNATIONAL JOURNAL OF TOXICOLOGY (2006)
Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes:: Identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1
TKH Chang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2006)
Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: Comparison of a milk thistle and black cohosh product to rifampin and clarithromycin
B Gurley et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2006)
Ginger significantly decreased the oral bioavailability of cyclosporine in rats
Hsiu-Mei Chiang et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2006)
Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans
BJ Gurley et al.
DRUG METABOLISM AND DISPOSITION (2006)
Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells
Liping Du et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2006)
Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic
DM Davenport et al.
FOOD AND CHEMICAL TOXICOLOGY (2005)
Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells:: Biphasic effect on CYP1A1
R Vrzal et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Anticonvulsant effect of Hypericum perforatum:: role of nitric oxide
H Hosseinzadeh et al.
JOURNAL OF ETHNOPHARMACOLOGY (2005)
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extract
G Arold et al.
PLANTA MEDICA (2005)
Induction of phase I, II and III drug metabolism/transport by xenobiotics
CJ Xu et al.
ARCHIVES OF PHARMACAL RESEARCH (2005)
Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
E Mills et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
T Nabekura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects
XM Jiang et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2004)
Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females
M Wenk et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2004)
St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism
C Tannergren et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole
LS Wang et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis
MY Lai et al.
PLANTA MEDICA (2004)
Pharmacogenetics and herb-drug interactions:: experience with Ginkgo biloba and omeprazole
OQP Yin et al.
PHARMACOGENETICS (2004)
Interaction of St John's wort with conventional drugs: systematic review of clinical trials
E Mills et al.
BRITISH MEDICAL JOURNAL (2004)
Effect of St. John's Wort on the pharmacokinetics of theophylline in healthy volunteers
T Morimoto et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2004)
Herbal modulation of P-glycoprotein
SF Zhou et al.
DRUG METABOLISM REVIEWS (2004)
The influence of St. John's Wort on the pharmacokinetics and protein binding of imatinib mesylate
P Smith
PHARMACOTHERAPY (2004)
Sulfotransferases: Structure, mechanism, biological activity, inhibition, and synthetic utility
E Chapman et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2
M Spiecker et al.
CIRCULATION (2004)
Human cytochrome P450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components
P Chatterjee et al.
DRUG METABOLISM AND DISPOSITION (2003)
Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme
JS Markowitz et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)
Coadministration of milk thistle and indinavir in healthy subjects
R DiCenzo et al.
PHARMACOTHERAPY (2003)
Effect of flavonoids on MRP1-mediated transport in Panc-1 cells
H Nguyen et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Coordinate induction of both cytochrome P4503A and MDRI by St John's wort in healthy subjects
GK Dresser et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)
Multiple-dose administration of Ginkgo biloba did not affect cytochrome P-450 2D6 or 3A4 activity in normal volunteers
JS Markowitz et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2003)
Ginkgo biloba extract markedly induces pentoxyresorufin O-dealkylase activity in rats
K Umegaki et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2002)
Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans
BJ Gurley et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's Wort (Hypericum perforatum)
A Johne et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2002)
Different effects of St John's Wort on the pharmacokinetics of simvastatin and pravastatin
K Sugimoto et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2001)
St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
LB Moore et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Inhibitory effects of silibinin on cytochrome P-450 enzymes in human liver microsomes
S Beckmann-Knopp et al.
PHARMACOLOGY & TOXICOLOGY (2000)