Evaluation of Prostate Cancer with 11C-Acetate PET/CT

In this article, we will first describe the metabolic fate of C-11-acetate; then discuss its biodistribution in health and disease; and subsequently focus on its key clinical applications, the detection and localization of prostate cancer tissue in patients with primary or recurrent disease. Finally, we will discuss the potential role of C-11-acetate in the context of other prostate cancer imaging probes and non-radionuclide-based imaging approaches.