4.7 Article

TDD-UNet:Transformer with double decoder UNet for COVID-19 lesions segmentation

Journal

COMPUTERS IN BIOLOGY AND MEDICINE
Volume 151, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compbiomed.2022.106306

Keywords

COVID-19; UNet; Transformer; Dual decoding module; Self-attention

Funding

  1. National Natural Science Foundation of China
  2. Natu-ral Science Foundation of Hunan Province of China
  3. Hunan provincial base for scientific and technological innovation cooperation
  4. [61504055]
  5. [61701218]
  6. [2020JJ4514]
  7. [2020JJ4519]

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The outbreak of COVID-19 has brought severe health risks globally. In this study, we propose a Transformer-based double decoder UNet model named TDD-UNet for COVID-19 lesion segmentation. The model incorporates multi-head self-attention of the Transformer and a dual decoder structure to extract global context information and improve segmentation results. Quantitative analysis and comparison on multiple datasets demonstrate the effectiveness of our proposed method in segmenting COVID-19 lesions.
The outbreak of new coronary pneumonia has brought severe health risks to the world. Detection of COVID-19 based on the UNet network has attracted widespread attention in medical image segmentation. However, the traditional UNet model is challenging to capture the long-range dependence of the image due to the limitations of the convolution kernel with a fixed receptive field. The Transformer Encoder overcomes the long-range dependence problem. However, the Transformer-based segmentation approach cannot effectively capture the fine-grained details. We propose a transformer with a double decoder UNet for COVID-19 lesions segmentation to address this challenge, TDD-UNet. We introduce the multi-head self-attention of the Transformer to the UNet encoding layer to extract global context information. The dual decoder structure is used to improve the result of foreground segmentation by predicting the background and applying deep supervision. We performed quantitative analysis and comparison for our proposed method on four public datasets with different modalities, including CT and CXR, to demonstrate its effectiveness and generality in segmenting COVID-19 lesions. We also performed ablation studies on the COVID-19-CT-505 dataset to verify the effectiveness of the key components of our proposed model. The proposed TDD-UNet also achieves higher Dice and Jaccard mean scores and the lowest standard deviation compared to competitors. Our proposed method achieves better segmentation results than other state-of-the-art methods.

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