Journal
COLORECTAL DISEASE
Volume 25, Issue 4, Pages 562-572Publisher
WILEY
DOI: 10.1111/codi.16462
Keywords
cancer; pain; pain management; pelvic exenteration; surgery
Categories
Ask authors/readers for more resources
This systematic review aimed to study the impact of pelvic exenteration surgery on the survival rate of patients with advanced colorectal cancer. The study found that postoperative pain was common, and the presence of preoperative pain predicted adverse pain outcomes in the postoperative period, with more extensive resections being associated with a higher likelihood of pain.
AimPelvic exenteration surgery can improve survival in people with advanced colorectal cancer. This systematic review aimed to review pain intensity and other outcomes, for example the management of pain, the relationship between pain and the extent of surgery and the impact of pain on short-term outcomes. MethodElectronic databases were searched from inception to 1 May 2021. We included interventional studies of adults with any indication for pelvic exenteration surgery that also reported pain outcomes. Risk of bias was assessed using ROBINS-1. ResultsThe search found 21 studies that reported pain following pelvic exenteration [n = 1317 patients, mean age 58.4 years (SD 4.8)]. Ten studies were judged to be at moderate risk of bias. Before pelvic exenteration, pain was reported by 19%-100% of patients. Five studies used validated measures of pain intensity. No study measured pain at all three time points in the surgical journey. The presence of pain before surgery predicted postoperative adverse pain outcomes, and pain is more likely to be experienced in those who require wider resections, including bone resection. ConclusionConsidering that pain following pelvic exenteration is commonly described by patients, the literature suggests that this symptom is not being measured and therefore addressed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available