4.3 Review

Aspergillus infection in chronic obstructive pulmonary diseases

Journal

CLINICAL RESPIRATORY JOURNAL
Volume 17, Issue 3, Pages 129-138

Publisher

WILEY
DOI: 10.1111/crj.13585

Keywords

chronic obstructive pulmonary disease (COPD); chronic pulmonary aspergillosis (CPA); invasive pulmonary aspergillosis (IPA)

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Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease characterized by airway obstruction and alveolar destruction. The use of antibiotics, glucocorticoids, immunosuppressants, and other drugs has led to an increase in pulmonary fungal infections, particularly aspergillus infections, in COPD patients. Aspergillus infection in COPD patients can manifest as sensitization, chronic pulmonary aspergillosis (CPA), and invasive pulmonary aspergillosis (IPA). This review provides an overview of the diagnosis and treatment of aspergillus infection in COPD patients.
Chronic obstructive pulmonary disease (COPD) is a chronic airway non-specific inflammatory disease characterised by airway obstruction and alveolar destruction. In recent years, due to the extensive use of antibiotics, glucocorticoids, immunosuppressants and other drugs, pulmonary fungal infection in patients with AECOPD, especially aspergillus infection, has gradually increased. The forms of aspergillus infection present in COPD patients include sensitisation, chronic pulmonary aspergillosis (CPA) and invasive pulmonary aspergillosis (IPA). This review will summarise diagnostic and treatment of aspergillus in COPD patients.

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