Journal
JOURNAL OF NUCLEAR CARDIOLOGY
Volume 24, Issue 1, Pages 86-99Publisher
SPRINGER
DOI: 10.1007/s12350-016-0502-7
Keywords
PET imaging; fluorodeoxyglucose (FDG); metabolism; inflammation
Funding
- NHLBI NIH HHS [K24 HL113128, T32 HL076136] Funding Source: Medline
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Although the number of clinical applications for fluorine-18 fluorodeoxyglucose (F-18-FDG) cardiac positron emission tomography (PET) has continued to grow, there remains a lack of consensus regarding the ideal method of suppressing normal myocardial glucose utilization for image optimization. This review describes various patient preparation protocols that have been used as well as the success rates achieved in different studies. Collectively, the available literature supports using a high-fat, no-carbohydrate diet for at least two meals with a fast of 4-12 hours prior to F-18-FDG PET imaging and suggests that isolated fasting for less than 12 hours and supplementation with food or drink just prior to imaging should be avoided. Each institution should adopt a protocol and continuously monitor its effectiveness with a goal to achieve adequate myocardial suppression in greater than 80% of patients.
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