☆ 4.7 Article

Synergistic strategy constructed hydrogel-aerogel biphase gel (HAB-gel) with self-negative-pressure exudate absorption, M2 macrophage-polarized and antibacterial for chronic wound treatment

CHEMICAL ENGINEERING JOURNAL (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Multidisciplinary

A Logic-Based Diagnostic and Therapeutic Hydrogel with Multistimuli Responsiveness to Orchestrate Diabetic Bone Regeneration

Dize Li et al.

Summary: By designing a double-network hydrogel, a diagnostic and therapeutic approach for diabetic bone regeneration has been developed. The hydrogel exhibits logic-based drug release and mechanical adaptability, and enhances osteogenesis in diabetic bone defects by regulating macrophage polarization. This study provides critical insights into the design and biological mechanism of dual-logic-based tissue-engineering strategies for diabetic bone regeneration.

ADVANCED MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

An Activatable Afterglow/MRI Bimodal Nanoprobe with Fast Response to H2S for In Vivo Imaging of Acute Hepatitis

Wenhui Zeng et al.

Summary: The study introduces a novel H2S-activatable bimodal probe F1-GdNP for accurate detection of hepatic hydrogen sulfide, showing high sensitivity and specificity for monitoring acute hepatitis through evaluation of CSE activity in living mice. The probe demonstrates potential for sensitive afterglow imaging of increased hepatic H2S levels and correlates well with upregulated CSE activity in the liver.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Add to Collection

Article Engineering, Biomedical

A novel bioactive polyurethane with controlled degradation and L-Arg release used as strong adhesive tissue patch for hemostasis and promoting wound healing

Faxing Zou et al.

Summary: Effective strategy of hemostasis and promoting angiogenesis is crucial in modern medicine. This study developed a novel tissue adhesive, G-DLPUs, which showed excellent shape-adaptive adhesion and enhanced wound healing by releasing L-Arg and generating NO during degradation. The G-DLPUs also demonstrated promising results in reducing liver bleeding and improving wound care in animal models.

BIOACTIVE MATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

A self-crosslinking, double-functional group modified bacterial cellulose gel used for antibacterial and healing of infected wound

Yajie Xie et al.

Summary: A bacterially-derived cellulose modified with bifunctional groups was combined with chitosan to create a composite material with enhanced antimicrobial properties. The composites exhibit directional adhesion antibacterial effects, effectively inhibiting bacterial proliferation on wounds.

BIOACTIVE MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Engineering Platelet-Rich Plasma Based Dual-Network Hydrogel as a Bioactive Wound Dressing with Potential Clinical Translational Value

Xiang Zhang et al.

Summary: The study developed an engineered PRP dual-network hydrogel (DN gel) based on sodium alginate, which has improved gelling property and sustained release of growth factors, showing great potential for the next generation of PRP-based bioactive wound dressings.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Physical

Polymersome Wound Dressing Spray Capable of Bacterial Inhibition and H2S Generation for Complete Diabetic Wound Healing

Danqing Liu et al.

Summary: Diabetic wounds are difficult to heal due to bacterial infection and decreased cell proliferation and migration. A polymersome-based wound dressing spray was shown to inhibit bacteria, generate H2S, and promote cell growth and angiogenesis in diabetic wounds, offering a new insight into effective treatment.

CHEMISTRY OF MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Green Tea Derivative Driven Smart Hydrogels with Desired Functions for Chronic Diabetic Wound Treatment

Xiaodan Zhao et al.

Summary: This study developed a smart hydrogel dressing through copolymerization of catechol groups and epigallocatechin-3-gallate (EGCG) with acrylamide, providing adequate mechanical properties, self-healing capability, and tissue adhesiveness. The substantial release of EGCG from the hydrogel enables multiple therapeutic effects, facilitates easy dressing change, and offers a convenient and effective method for the management of chronic diabetic wounds.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Silk-Inspired In Situ Hydrogel with Anti-Tumor Immunity Enhanced Photodynamic Therapy for Melanoma and Infected Wound Healing

Xiaoxuan Tang et al.

Summary: A silk-based hydrogel system has been developed for improved cancer therapy and enhanced wound healing, showing promising results in suppressing tumor recurrence and promoting tissue regeneration.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Medicine, Research & Experimental

H2S prevents peripheral immune cell invasion, increasing [Ca2+]i and excessive phagocytosis following hypoxia-ischemia injury in neonatal mice

Tingting Li et al.

Summary: The study found that L-Cysteine treatment after neonatal hypoxia-ischemia brain injury can modulate immune cell populations, inhibit peripheral immune cell invasion, reduce Ca2+ mobilization, and improve neurobehavioral deficits.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Add to Collection

Article Engineering, Biomedical

Bioactive antiinflammatory antibacterial hemostatic citrate-based dressing with macrophage polarization regulation for accelerating wound healing and hair follicle neogenesis

Wenguang Liu et al.

Summary: The study introduced a novel dressing for wound healing and hair follicle regeneration, showcasing anti-inflammatory, antibacterial, and cytocompatible properties.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Multifunctional Injectable Hydrogel Dressings for Effectively Accelerating Wound Healing: Enhancing Biomineralization Strategy

Hui Zhang et al.

Summary: In this study, Gel-DA was used as a biotemplate to synthesize Gel-DA@Ag NPs with antioxidant activity and NIR laser irradiation synergistic antibacterial behavior for the first time. These NPs were then incorporated into guar gum based hydrogels to achieve remolding, injectable, and self-healing properties. The multifunctional hydrogels demonstrated the ability to completely cover irregular wound shapes and accelerate wound healing under NIR, with the appearance of skin appendages like hair follicles and blood vessels.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Poly(ionic liquid)/Ce-Based Antimicrobial Nanofibrous Membrane for Blocking Drug-Resistance Dissemination from MRSA-Infected Wounds

Zhenhong Luo et al.

Summary: The antimicrobial PIL-Ce membranes showed high efficiencies in eradicating bacteria and disintegrating drug-resistant genes, with potential application as a new green wound dressing to block the spread of drug resistance in clinical settings.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Multifunctional DNA Hydrogels with Hydrocolloid-Cotton Structure for Regeneration of Diabetic Infectious Wounds

Liping Zhou et al.

Summary: The multifunctional DNA hydrogel dressing offers a wide range of functions such as absorbability, self-healing ability, antibacterial properties, and tissue regeneration promotion. Its advanced collaborative strategy provides an effective method for cascade management of clinical guided tissue regeneration, accelerating nerve and hair regeneration.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Self-Amplification Immunomodulatory Strategy for Tissue Regeneration in Diabetes Based on Cytokine-ZIFs System

Geyong Guo et al.

Summary: The study proposed a new strategy to treat tissue regeneration disorders in diabetes by restoring macrophage function and reconstructing the immune microenvironment using the IL@ZIF nano-platform. IL@ZIF effectively protects IL-33, promotes M2 macrophage polarization, exacerbates the inflammatory response, and accelerates tissue regeneration.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Biomimetic Glucose Trigger-Insulin Release System Based on Hydrogel Loading Bidentate β-Cyclodextrin

Renqi Wang et al.

Summary: Initiated by the specific binding between D-glucose and biological receptors, the delicate metabolic system in the human body regulates blood D-glucose levels, with insulin release playing a crucial role in preventing hyperglycemia and type I diabetes. A novel hydrogel system is presented, which responds specifically to D-glucose and releases insulin on demand, showing potential therapeutic efficacy in treating hyperglycemia.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Engineering Bioactive M2 Macrophage-Polarized Anti-Inflammatory, Antioxidant, and Antibacterial Scaffolds for Rapid Angiogenesis and Diabetic Wound Repair

Zhuolong Tu et al.

Summary: A conductive hydrogel scaffold with M2 phenotype-enabled properties has been developed to enhance diabetic wound repair by promoting anti-inflammation and antioxidant activities.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Ubiquitination Flow Repressors: Enhancing Wound Healing of Infectious Diabetic Ulcers through Stabilization of Polyubiquitinated Hypoxia-Inducible Factor-1α by Theranostic Nitric Oxide Nanogenerators

Yiqi Yang et al.

Summary: The study presents an intelligent near-infrared-triggered nitric oxide nanogenerator that enhances angiogenesis, inhibits bacterial infection, and maintains the stability of HIF-1 alpha protein for treating diabetic ulcers.

ADVANCED MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Design of a biofluid-absorbing bioactive sandwich-structured Zn-Si bioceramic composite wound dressing for hair follicle regeneration and skin burn wound healing

Zhaowenbin Zhang et al.

Summary: A sandwich-structured wound dressing with Janus membrane property was fabricated, showing excellent exudate absorption and bioactivity for promoting hair follicle regeneration and wound healing through the synergistic effect of Zn2+ and SiO32- ions.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

A Novel Double-Crosslinking-Double-Network Design for Injectable Hydrogels with Enhanced Tissue Adhesion and Antibacterial Capability for Wound Treatment

Lei Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Add to Collection

Article Chemistry, Physical

Preparation of macroporous polyvinyl alcohol formaldehyde based hydrogels and their dual thermo- and pH-responsive behavior

Kai Shi et al.

APPLIED SURFACE SCIENCE (2020)

Add to Collection

Review Engineering, Biomedical

Current status and future outlook of nano-based systems for burn wound management

Morteza Abazari et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2020)

Add to Collection

Review Engineering, Biomedical

Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing

Zejun Xu et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Add to Collection

Article Immunology

Suppression of lipopolysaccharide-induced activation of RAW 264.7 macrophages by Se-methylseleno-L-cysteine

Guang Wang et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

Add to Collection

Article Engineering, Biomedical

A novel waterborne polyurethane with biodegradability and high flexibility for 3D printing

Zhaoxuan Feng et al.

BIOFABRICATION (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Adhesive Hemostatic Conducting Injectable Composite Hydrogels with Sustained Drug Release and Photothermal Antibacterial Activity to Promote Full-Thickness Skin Regeneration During Wound Healing

Yongping Liang et al.

SMALL (2019)

Add to Collection

Article Neurosciences

L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice

Xin Zhou et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)

Add to Collection

Article Chemistry, Physical

The antibacterial stability of poly(dopamine) in-situ reduction and chelation nano-Ag based on bacterial cellulose network template

Yajie Xie et al.

APPLIED SURFACE SCIENCE (2019)

Add to Collection

Article Engineering, Biomedical

Novel H2S-Releasing hydrogel for wound repair via in situ polarization of M2 macrophages

Jiang Wu et al.

BIOMATERIALS (2019)

Add to Collection

Article Chemistry, Applied

Highly transparent, highly flexible composite membrane with multiple antimicrobial effects used for promoting wound healing

Yansen Wang et al.

CARBOHYDRATE POLYMERS (2019)

Add to Collection

Article Multidisciplinary Sciences

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

Michael D. Kornberg et al.

SCIENCE (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Shape memory materials based on adamantane-containing polyurethanes

Faxing Zou et al.

RSC ADVANCES (2018)

Add to Collection

Article Nanoscience & Nanotechnology

Superfast and Reversible Thermoresponse of Poly(N-isopropylacrylamide) Hydrogels Grafted on Macroporous Poly(vinyl alcohol) Formaldehyde Sponges

Yanxiong Pan et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Add to Collection

Article Materials Science, Multidisciplinary

Shape-adaptive composite foams with high expansion and absorption used for massive hemorrhage control and irregular wound treatment

Yansen Wang et al.

APPLIED MATERIALS TODAY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Self-Assembled Wound Dressings Silence MMP-9 and Improve Diabetic Wound Healing In Vivo

Steven A. Castleberry et al.

ADVANCED MATERIALS (2016)

Add to Collection

Article Biochemistry & Molecular Biology

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

Roger Geiger et al.

CELL (2016)

Add to Collection

Review Dermatology

Diabetic foot wounds: the value of negative pressure wound therapy with instillation

Luca Dalla Paola

INTERNATIONAL WOUND JOURNAL (2013)

Add to Collection

Review Dermatology

Negative pressure wound therapy: past, present and future

Dennis P. Orgill et al.

INTERNATIONAL WOUND JOURNAL (2013)

Add to Collection

Article Pharmacology & Pharmacy

Antimicrobial properties of cyclodextrin-antiseptics-complexes determined by microplate laser nephelometry and ATP bioluminescence assay

Susanne Finger et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)

Add to Collection

© Peeref 2019-2024. All rights reserved.