Sequential click modification of a lithium-ion endohedral fullerene connecting small molecules through a dieneazide linker

A versatile method for the chemical modification of a lithium-ion endohedral fullerene (Li+@C-60) to connect various small molecules is described. The designed dieneazide linker enables the facile connection of Li+@C-60 with small molecules bearing a terminal alkyne via Huisgen annulation and a subsequent Diels-Alder reaction. This strategy significantly expands the diversity of small molecules to be attached by Li+@C-60.

Automated summary

A versatile method is described for chemically modifying a lithium-ion endohedral fullerene (Li+@C-60) to connect various small molecules. The designed dieneazide linker enables easy connection of Li+@C-60 with small molecules bearing a terminal alkyne via Huisgen annulation and a subsequent Diels-Alder reaction. This strategy significantly expands the diversity of small molecules that can be attached by Li+@C-60.